Lendahl, Urban

A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, M., He, L., Mäe, M. A., Andrae, J., Ando, K., Del Gaudio, F., Nahar, K., Lebouvier, T., Laviña, B., Gouveia, L., et al. (2018) · Nature

Barrier Structure and Function StudiesSingle-cell and spatial transcriptomics

Cited by 1,892

Hypoxia requires Notch signaling to maintain the undifferentiated cell state

Gustafsson, M. V., Zheng, X., Pereira, T., Gradin, K., Jin, S., Lundkvist, J., Ruas, J. L., Poellinger, L., Lendahl, U., & Bondesson, M. (2005) · Developmental Cell

Developmental Biology and Gene RegulationCancer, Hypoxia, and Metabolism

Cited by 1,109

Notch signaling: simplicity in design, versatility in function

Andersson, E. R., Sandberg, R., & Lendahl, U. (2011) · Development

Developmental Biology and Gene RegulationWnt/β-catenin signaling in development and cancer

Cited by 950

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

Sahlgren, C., Gustafsson, M. V., Jin, S., Poellinger, L., & Lendahl, U. (2008) · Proceedings of the National Academy of Sciences

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 823

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He, L., Vanlandewijck, M., Mäe, M. A., Andrae, J., Ando, K., Del Gaudio, F., Nahar, K., Lebouvier, T., Laviña, B., Gouveia, L., et al. (2018) · Scientific Data

Single-cell and spatial transcriptomicsAngiogenesis and VEGF in Cancer

Cited by 413

Abnormal Reaction to Central Nervous System Injury in Mice Lacking Glial Fibrillary Acidic Protein and Vimentin

Pekny, M., Johansson, C. B., Eliasson, C., Stakeberg, J., Wallén, Å., Perlmann, T., Lendahl, U., Betsholtz, C., Berthold, C.-H., & Frisén, J. (1999) · The Journal of Cell Biology

Spinal Cord Injury ResearchSkin and Cellular Biology Research

Cited by 405

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

Zhao, J., Liu, T., Jin, S., Wang, X., Qu, M., Uhlén, P., Tomilin, N., Shupliakov, O., Lendahl, U., & Nistér, M. (2011) · The EMBO Journal

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 370

Specification of CNS macrophage subsets occurs postnatally in defined niches

Masuda, T., Amann, L., Monaco, G., Sankowski, R., Staszewski, O., Krueger, M., Del Gaudio, F., He, L., Paterson, N., Nent, E., et al. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 294

Impact of Epithelial–Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ

Strell, C., Paulsson, J., Jin, S.-B., Tobin, N. P., Mezheyeuski, A., Roswall, P., Mutgan, C., Mitsios, N., Johansson, H., Wickberg, S. M., et al. (2019) · JNCI: Journal of the National Cancer Institute

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 158

Molecular anatomy of adult mouse leptomeninges

Pietilä, R., Del Gaudio, F., He, L., Vázquez-Liébanas, E., Vanlandewijck, M., Muhl, L., Mocci, G., Bjørnholm, K. D., Lindblad, C., Fletcher-Sandersjöö, A., et al. (2023) · Neuron

Barrier Structure and Function StudiesSingle-cell and spatial transcriptomics

Cited by 145

Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System

Henshall, T. L., Keller, A., He, L., Johansson, B. R., Wallgard, E., Raschperger, E., Mäe, M. A., Jin, S., Betsholtz, C., & Lendahl, U. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology

Barrier Structure and Function StudiesCerebrovascular and genetic disorders

Cited by 145

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID-19

He, L., Mäe, M. A., Muhl, L., Sun, Y., Pietilä, R., Nahar, K., Liébanas, E. V., Fagerlund, M. J., Oldner, A., Liu, J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 116

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Santio, N. M., Landor, S. K.-J., Vahtera, L., Ylä-Pelto, J., Paloniemi, E., Imanishi, S. Y., Corthals, G., Varjosalo, M., Manoharan, G. B., Uri, A., et al. (2016) · Oncotarget

Developmental Biology and Gene RegulationPI3K/AKT/mTOR signaling in cancer

Cited by 65