Shoelson, Steven E.

Inflammation and insulin resistance

Shoelson, S. E. (2006) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 4,769

Type 2 diabetes as an inflammatory disease

Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology

Adipokines, Inflammation, and Metabolic DiseasesDiabetes Treatment and Management

Cited by 3,737

Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

Cai, D., Yuan, M., Frantz, D. F., Melendez, P. A., Hansen, L., Lee, J., & Shoelson, S. E. (2005) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesNF-κB Signaling Pathways

Cited by 2,245

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

Feuerer, M., Herrero, L., Cipolletta, D., Naaz, A., Wong, J., Nayer, A., Lee, J., Goldfine, A. B., Benoist, C., Shoelson, S., et al. (2009) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 2,145

Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

Yuan, M., Konstantopoulos, N., Lee, J., Hansen, L., Li, Z.-W., Karin, M., & Shoelson, S. E. (2001) · Science

Adipokines, Inflammation, and Metabolic DiseasesNF-κB Signaling Pathways

Cited by 1,884

Obesity, Inflammation, and Insulin Resistance

Shoelson, S. E., Herrero, L., & Naaz, A. (2007) · Gastroenterology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,806

IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

Cai, D., Frantz, J. D., Tawa, N. E., Melendez, P. A., Oh, B.-C., Lidov, H. G. W., Hasselgren, P.-O., Frontera, W. R., Lee, J., Glass, D. J., et al. (2004) · Cell

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 1,367

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

Cipolletta, D., Feuerer, M., Li, A., Kamei, N., Lee, J., Shoelson, S. E., Benoist, C., & Mathis, D. (2012) · Nature

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,143

Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

Bjørbæk, C., Elmquist, J. K., Frantz, J. D., Shoelson, S. E., & Flier, J. S. (1998) · Molecular Cell

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,014

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

Rui, L., Yuan, M., Frantz, D., Shoelson, S., & White, M. F. (2002) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

Cited by 904

Prevention of fat-induced insulin resistance by salicylate

Kim, J. K., Kim, Y.-J., Fillmore, J. J., Chen, Y., Moore, I., Lee, J., Yuan, M., Li, Z. W., Karin, M., Perret, P., et al. (2001) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 737

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

Hundal, R. S., Petersen, K. F., Mayerson, A. B., Randhawa, P. S., Inzucchi, S., Shoelson, S. E., & Shulman, G. I. (2002) · Journal of Clinical Investigation

Diabetes Treatment and ManagementAdipokines, Inflammation, and Metabolic Diseases

Cited by 557

Inflammation and the IKKβ/IκB/NF-κB axis in obesity- and diet-induced insulin resistance

Shoelson, S. E., Lee, J., & Yuan, M. (2003) · International Journal of Obesity

Adipokines, Inflammation, and Metabolic DiseasesNF-κB Signaling Pathways

Cited by 474

Crystal Structure of Human Frataxin

Dhe-Paganon, S., Shigeta, R., Chi, Y.-I., Ristow, M., & Shoelson, S. E. (2000) · Journal of Biological Chemistry

Enzyme Structure and FunctionGenetic Neurodegenerative Diseases

Cited by 226

Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Yamamoto, Y., Liang, M., Munesue, S., Deguchi, K., Harashima, A., Furuhara, K., Yuhi, T., Zhong, J., Akther, S., Goto, H., et al. (2019) · Communications Biology

Neuroendocrine regulation and behaviorBarrier Structure and Function Studies

Cited by 171

Three mutant insulins in man

Shoelson, S., Haneda, M., Blix, P., Nanjo, A., Sanke, T., Inouye, K., Steiner, D., Rubenstein, A., & Tager, H. (1983) · Nature

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 157

Getting away from glucose: fanning the flames of obesity-induced inflammation

Shoelson, S. E., & Goldfine, A. B. (2009) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 98

Banking on ATM as a new target in metabolic syndrome

Shoelson, S. E. (2006) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 29

Crystal Structures of Human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating Protein (RabGAP) Domains Reveal Critical Elements for GLUT4 Translocation

Park, S.-Y., Jin, W., Woo, J. R., & Shoelson, S. E. (2011) · Journal of Biological Chemistry

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 25

NFκB Regulates Muscle Development and Mitochondrial Function

Valentine, J. M., Li, M. E., Shoelson, S. E., Zhang, N., Reddick, R. L., & Musi, N. (2020) · The Journals of Gerontology: Series A

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 23

Inflammation and obesity: STAMPing out insulin resistance?

Abedini, A., & Shoelson, S. E. (2007) · Immunology & Cell Biology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 18