Huang, Yiyun

In vivo evidence of lower synaptic vesicle density in schizophrenia

Radhakrishnan, R., Skosnik, P. D., Ranganathan, M., Naganawa, M., Toyonaga, T., Finnema, S., Hillmer, A. T., Esterlis, I., Huang, Y., Nabulsi, N., et al. (2021) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 100

First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer

Naganawa, M., Nabulsi, N., Henry, S., Matuskey, D., Lin, S.-F., Slieker, L., Schwarz, A. J., Kant, N., Jesudason, C., Ruley, K., et al. (2021) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 94

Reduced amygdala serotonin transporter binding in posttraumatic stress disorder

Murrough, J. W., Huang, Y., Hu, J., Henry, S., Williams, W., Gallezot, J.-D., Bailey, C. R., Krystal, J. H., Carson, R. E., & Neumeister, A. (2011) · Biological Psychiatry

Posttraumatic Stress Disorder ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 92

In Vivo Synaptic Density Imaging with 11 C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease

Toyonaga, T., Smith, L. M., Finnema, S. J., Gallezot, J.-D., Naganawa, M., Bini, J., Mulnix, T., Cai, Z., Ropchan, J., Huang, Y., et al. (2019) · Journal of Nuclear Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79

Reduced synaptic vesicle protein 2A binding in temporal lobe epilepsy: A [11C]UCB‐J positron emission tomography study

Finnema, S. J., Toyonaga, T., Detyniecki, K., Chen, M., Dias, M., Wang, Q., Lin, S., Naganawa, M., Gallezot, J., Lu, Y., et al. (2020) · Epilepsia

Epilepsy research and treatmentMedical Imaging Techniques and Applications

Cited by 78

A single-center, open-label positron emission tomography study to evaluate brivaracetam and levetiracetam synaptic vesicle glycoprotein 2A binding in healthy volunteers

Finnema, S. J., Rossano, S., Naganawa, M., Henry, S., Gao, H., Pracitto, R., Maguire, R. P., Mercier, J., Kervyn, S., Nicolas, J., et al. (2019) · Epilepsia

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 65

Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A

Li, S., Naganawa, M., Pracitto, R., Najafzadeh, S., Holden, D., Henry, S., Matuskey, D., Emery, P. R., Cai, Z., Ropchan, J., et al. (2021) · European Journal of Nuclear Medicine and Molecular Imaging

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 61

Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)

Li, S., Cai, Z., Zhang, W., Holden, D., Lin, S.-F., Finnema, S. J., Shirali, A., Ropchan, J., Carre, S., Mercier, J., et al. (2019) · European Journal of Nuclear Medicine and Molecular Imaging

Radiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and Applications

Cited by 59

Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

D’Souza, D. C., Radhakrishnan, R., Naganawa, M., Ganesh, S., Nabulsi, N., Najafzadeh, S., Ropchan, J., Ranganathan, M., Cortes-Briones, J., Huang, Y., et al. (2021) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 55

Modulation of amphetamine-induced dopamine release by group II metabotropic glutamate receptor agonist LY354740 in non-human primates studied with positron emission tomography

van Berckel, B. N. M., Kegeles, L. S., Waterhouse, R., Guo, N., Hwang, D.-R., Huang, Y., Narendran, R., Van Heertum, R., & Laruelle, M. (2006) · Neuropsychopharmacology

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 43

Binding of the synaptic vesicle radiotracer [ 11 C]UCB-J is unchanged during functional brain activation using a visual stimulation task

Smart, K., Liu, H., Matuskey, D., Chen, M.-K., Torres, K., Nabulsi, N., Labaree, D., Ropchan, J., Hillmer, A. T., Huang, Y., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism

Medical Imaging Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Cited by 42

Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11 C‐UCB‐J positron emission tomography study in humans

Angarita, G. A., Worhunsky, P. D., Naganawa, M., Toyonaga, T., Nabulsi, N. B., Li, C. R., Esterlis, I., Skosnik, P. D., Radhakrishnan, R., Pittman, B., et al. (2022) · Addiction Biology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 38

Quantification of SV2A Binding in Rodent Brain Using [18F]SynVesT-1 and PET Imaging

Sadasivam, P., Fang, X. T., Toyonaga, T., Lee, S., Xu, Y., Zheng, M.-Q., Spurrier, J., Huang, Y., Strittmatter, S. M., Carson, R. E., et al. (2021) · Molecular Imaging and Biology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 31

APOE ε4 is associated with decreased synaptic density in cognitively impaired participants

He, K., Li, B., Wang, J., Wang, Y., You, Z., Chen, X., Chen, H., Li, J., Huang, Q., Guo, Q., et al. (2024) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 29

First-in-Human Study of18F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding

Drake, L. R., Wu, Y., Naganawa, M., Asch, R., Zheng, C., Najafzadeh, S., Pracitto, R., Lindemann, M., Li, S., Ropchan, J., et al. (2024) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 18

Low-Dose Augmentation With Buprenorphine for Treatment-Resistant Depression: A Multisite Randomized Controlled Trial With Multimodal Assessment of Target Engagement

Lee, H. H., Blumberger, D. M., Lenze, E. J., Anderson, S. J., Barch, D. M., Black, K. J., Cristancho, P., Daskalakis, Z. J., Eisenstein, S. A., Huang, Y., et al. (2022) · Biological Psychiatry Global Open Science

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 15

Impaired glymphatic function is associated with synaptic loss in cognitive impairment

He, K., Wang, J., Wu, J., Chen, X., Chen, H., Li, J., Guo, Q., Huang, Y. H., Guan, Y., Zhao, J., et al. (2026) · European Journal of Nuclear Medicine and Molecular Imaging

Cerebrospinal fluid and hydrocephalusDementia and Cognitive Impairment Research

Cited by 6

In vivo measurement of widespread synaptic loss and associated tau accumulation in early Alzheimer’s disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD

Mecca, A. P., O'Dell, R. S., Chen, M., Naganawa, M., Toyonaga, T., Godek, T. A., Harris, J. E., Bartlett, H. H., Zhao, W., Gallezot, J., et al. (2020) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 1