Huang, Yiyun

Prefrontal Dopamine D1Receptors and Working Memory in Schizophrenia

Abi-Dargham, A., Mawlawi, O., Lombardo, I., Gil, R., Martinez, D., Huang, Y., Hwang, D.-R., Keilp, J., Kochan, L., Van Heertum, R., et al. (2002) · The Journal of Neuroscience

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 724

Pet imaging of serotonin 1A receptor binding in depression

Drevets, W. C., Frank, E., Price, J. C., Kupfer, D. J., Holt, D., Greer, P. J., Huang, Y., Gautier, C., & Mathis, C. (1999) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 666

Imaging synaptic density in the living human brain

Finnema, S. J., Nabulsi, N. B., Eid, T., Detyniecki, K., Lin, S.-F., Chen, M.-K., Dhaher, R., Matuskey, D., Baum, E., Holden, D., et al. (2016) · Science Translational Medicine

Medical Imaging Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Cited by 575

Imaging Human Mesolimbic Dopamine Transmission with Positron Emission Tomography. Part II: Amphetamine-Induced Dopamine Release in the Functional Subdivisions of the Striatum

Martinez, D., Slifstein, M., Broft, A., Mawlawi, O., Hwang, D.-R., Huang, Y., Cooper, T., Kegeles, L., Zarahn, E., Abi-Dargham, A., et al. (2003) · Journal of Cerebral Blood Flow & Metabolism

Neurotransmitter Receptor Influence on BehaviorSchizophrenia research and treatment

Cited by 569

Increased Synaptic Dopamine Function in Associative Regions of the Striatum in Schizophrenia

Kegeles, L. S., Abi-Dargham, A., Frankle, W. G., Gil, R., Cooper, T. B., Slifstein, M., Hwang, D.-R., Huang, Y., Haber, S. N., & Laruelle, M. (2010) · Archives of General Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 565

Imaging Human Mesolimbic Dopamine Transmission with Positron Emission Tomography: I. Accuracy and Precision of D 2 Receptor Parameter Measurements in Ventral Striatum

Mawlawi, O., Martinez, D., Slifstein, M., Broft, A., Chatterjee, R., Hwang, D.-R., Huang, Y., Simpson, N., Ngo, K., Van Heertum, R., et al. (2001) · Journal of Cerebral Blood Flow & Metabolism

Neurotransmitter Receptor Influence on BehaviorMedical Imaging Techniques and Applications

Cited by 525

Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum

Martinez, D., Gil, R., Slifstein, M., Hwang, D.-R., Huang, Y., Perez, A., Kegeles, L., Talbot, P., Evans, S., Krystal, J., et al. (2005) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 445

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

Chen, M.-K., Mecca, A. P., Naganawa, M., Finnema, S. J., Toyonaga, T., Lin, S.-F., Najafzadeh, S., Ropchan, J., Lu, Y., McDonald, J. W., et al. (2018) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 431

Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia: A Positron Emission Tomographic Functional Magnetic Resonance Imaging Study

Slifstein, M., van de Giessen, E., Van Snellenberg, J., Thompson, J. L., Narendran, R., Gil, R., Hackett, E., Girgis, R., Ojeil, N., Moore, H., et al. (2015) · JAMA Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 398

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: A positron emission tomography study

Neumeister, A., Normandin, M. D., Pietrzak, R. H., Piomelli, D., Zheng, M. Q., Gujarro-Anton, A., Potenza, M. N., Bailey, C. R., Lin, S. F., Najafzadeh, S., et al. (2013) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchPosttraumatic Stress Disorder Research

Cited by 361

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Sandiego, C. M., Gallezot, J.-D., Pittman, B., Nabulsi, N., Lim, K., Lin, S.-F., Matuskey, D., Lee, J.-Y., O’Connor, K. C., Huang, Y., et al. (2015) · Proceedings of the National Academy of Sciences

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 356

Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine

Martinez, D., Narendran, R., Foltin, R. W., Slifstein, M., Hwang, D.-R., Broft, A., Huang, Y., Cooper, T. B., Fischman, M. W., Kleber, H. D., et al. (2007) · American Journal of Psychiatry

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 351

Cocaine Dependence and D2 Receptor Availability in the Functional Subdivisions of the Striatum: Relationship with Cocaine-Seeking Behavior

Martinez, D., Broft, A., Foltin, R. W., Slifstein, M., Hwang, D.-R., Huang, Y., Perez, A., Frankel, W. G., Cooper, T., Kleber, H. D., et al. (2004) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 306

Synthesis and Preclinical Evaluation of 11 C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

Nabulsi, N. B., Mercier, J., Holden, D., Carré, S., Najafzadeh, S., Vandergeten, M.-C., Lin, S.-F., Deo, A., Price, N., Wood, M., et al. (2016) · Journal of Nuclear Medicine

Radiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and Applications

Cited by 296

In vivo measurement of widespread synaptic loss in Alzheimer’s disease with SV2A PET

Mecca, A. P., Chen, M., O'Dell, R. S., Naganawa, M., Toyonaga, T., Godek, T. A., Harris, J. E., Bartlett, H. H., Zhao, W., Nabulsi, N. B., et al. (2020) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 288

Effect of a Triallelic Functional Polymorphism of the Serotonin-Transporter-Linked Promoter Region on Expression of Serotonin Transporter in the Human Brain

Parsey, R. V., Hastings, R. S., Oquendo, M. A., Hu, X., Goldman, D., Huang, Y.-Y., Simpson, N., Arcement, J., Huang, Y., Ogden, R. T., et al. (2006) · American Journal of Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 262

Kinetic evaluation and test–retest reproducibility of [ 11 C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

Finnema, S. J., Nabulsi, N. B., Mercier, J., Lin, S.-F., Chen, M.-K., Matuskey, D., Gallezot, J.-D., Henry, S., Hannestad, J., Huang, Y., et al. (2018) · Journal of Cerebral Blood Flow & Metabolism

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 218

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [ 11 C]UCB‐J

Mecca, A. P., O'Dell, R. S., Sharp, E. S., Banks, E. R., Bartlett, H. H., Zhao, W., Lipior, S., Diepenbrock, N. G., Chen, M., Naganawa, M., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 186

Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV 2A) ligand with preclinical evidence of high brain permeability and fast onset of action

Nicolas, J., Hannestad, J., Holden, D., Kervyn, S., Nabulsi, N., Tytgat, D., Huang, Y., Chanteux, H., Staelens, L., Matagne, A., et al. (2016) · Epilepsia

Epilepsy research and treatmentBarrier Structure and Function Studies

Cited by 169

First-in-Human Evaluation of 18 F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A

Naganawa, M., Li, S., Nabulsi, N., Henry, S., Zheng, M.-Q., Pracitto, R., Cai, Z., Gao, H., Kapinos, M., Labaree, D., et al. (2021) · Journal of Nuclear Medicine

Medical Imaging Techniques and ApplicationsRadiopharmaceutical Chemistry and Applications

Cited by 138

PET imaging of synaptic density: A new tool for investigation of neuropsychiatric diseases

Cai, Z., Li, S., Matuskey, D., Nabulsi, N., & Huang, Y. (2019) · Neuroscience Letters

Neuroscience and Neuropharmacology ResearchMedical Imaging Techniques and Applications

Cited by 131

Assessment of a white matter reference region for 11 C-UCB-J PET quantification

Rossano, S., Toyonaga, T., Finnema, S. J., Naganawa, M., Lu, Y., Nabulsi, N., Ropchan, J., De Bruyn, S., Otoul, C., Stockis, A., et al. (2020) · Journal of Cerebral Blood Flow & Metabolism

Medical Imaging Techniques and ApplicationsAdvanced MRI Techniques and Applications

Cited by 126

Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging

Han, L., Kong, D. K., Zheng, M.-Q., Murikinati, S., Ma, C., Yuan, P., Li, L., Tian, D., Cai, Q., Ye, C., et al. (2016) · ACS Nano

Nanoparticle-Based Drug DeliveryBarrier Structure and Function Studies

Cited by 122

PET Neuroimaging of Alzheimer's Disease: Radiotracers and Their Utility in Clinical Research

Bao, W., Xie, F., Zuo, C., Guan, Y., & Huang, Y. H. (2021) · Frontiers in Aging Neuroscience

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 102