Liesz, Arthur

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

Cserép, C., Pósfai, B., Lénárt, N., Fekete, R., László, Z. I., Lele, Z., Orsolits, B., Molnár, G., Heindl, S., Schwarcz, A. D., et al. (2020) · Science

Neuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling

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Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections

Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Förstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., et al. (2019) · Nature Neuroscience

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

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Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Colombo, A. V., Sadler, R. K., Llovera, G., Singh, V., Roth, S., Heindl, S., Sebastian Monasor, L., Verhoeven, A., Peters, F., Parhizkar, S., et al. (2021) · eLife

Alzheimer's disease research and treatmentsGut microbiota and health

Cited by 354

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

Liesz, A., Dalpke, A., Mracsko, E., Roth, S., Zhou, W., Yang, H., Na, S.-Y., Akhisaroglu, M., Fleming, T., Eigenbrod, T., et al. (2015) · The Journal of Neuroscience

Advanced Glycation End Products researchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 334

Systemic inflammation after stroke: implications for post‐stroke comorbidities

Simats, A., & Liesz, A. (2022) · EMBO Molecular Medicine

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 276

CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging

Kaya, T., Mattugini, N., Liu, L., Ji, H., Cantuti-Castelvetri, L., Wu, J., Schifferer, M., Groh, J., Martini, R., Besson-Girard, S., et al. (2022) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 224

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance

Xiang, X., Werner, G., Bohrmann, B., Liesz, A., Mazaheri, F., Capell, A., Feederle, R., Knuesel, I., Kleinberger, G., & Haass, C. (2016) · EMBO Molecular Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Young microglia restore amyloid plaque clearance of aged microglia

Daria, A., Colombo, A., Llovera, G., Hampel, H., Willem, M., Liesz, A., Haass, C., & Tahirovic, S. (2017) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 174

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

Sebastian Monasor, L., Müller, S. A., Colombo, A. V., Tanrioever, G., König, J., Roth, S., Liesz, A., Berghofer, A., Piechotta, A., Prestel, M., et al. (2020) · eLife

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 147

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Reifschneider, A., Robinson, S., van Lengerich, B., Gnörich, J., Logan, T., Heindl, S., Vogt, M. A., Weidinger, E., Riedl, L., Wind, K., et al. (2022) · The EMBO Journal

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

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Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning

Luo, J., Molbay, M., Chen, Y., Horvath, I., Kadletz, K., Kick, B., Zhao, S., Al-Maskari, R., Singh, I., Ali, M., et al. (2025) · Nature Biotechnology

Nanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery

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TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism

Feiten, A. F., Dahm, K., Schlepckow, K., van Lengerich, B., Suh, J. H., Reifschneider, A., Wefers, B., Bartos, L. M., Wind-Mark, K., de Weerd, L., et al. (2026) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease

Dinkel, L., Hummel, S., Zenatti, V., Malara, M., Tillmann, Y., Colombo, A., Monasor, L. S., Suh, J. H., Logan, T., Roth, S., et al. (2024) · Science Translational Medicine

Lysosomal Storage Disorders ResearchNeuroinflammation and Neurodegeneration Mechanisms

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Most prominent challenges in translational neuroscience and strategic solutions to bridge the gaps: Perspectives from an editorial board interrogation

Hermann, D. M., Bacigaluppi, M., Bassetti, C. L., Bassotti, G., Boltze, J., Chan, A., Dalkara, T., Denes, A., Diez-Tejedor, E., Dodel, R., et al. (2025) · Exploration of Neuroscience

Health and Medical Research ImpactsAnimal testing and alternatives

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