Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827 · see citing works

Computer visualization of three-dimensional image data using IMOD.

Kremer, J. R., Mastronarde, D., & Mcintosh, J. (1996) · Journal of Structural Biology · doi:10.1006/jsbi.1996.0013 · Cited by 5,770 · see citing works

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875 · see citing works

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913 · see citing works

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

Bederson, J. B., Pitts, L. H., Tsuji, M., Nishimura, M. C., Davis, R. L., & Bartkowski, H. (1986) · Stroke · doi:10.1161/01.str.17.3.472 · Cited by 2,681 · see citing works

The immunology of stroke: from mechanisms to translation

Iadecola, C., & Anrather, J. (2011) · Nature Medicine · doi:10.1038/nm.2399 · Cited by 2,596 · see citing works

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

Butovsky, O., Jedrychowski, M. P., Moore, C. S., Cialic, R., Lanser, A. J., Gabriely, G., Koeglsperger, T., Dake, B., Wu, P. M., Doykan, C. E., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3599 · Cited by 2,543 · see citing works

Experience-dependent structural synaptic plasticity in the mammalian brain

Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2699 · Cited by 1,934 · see citing works

Microglia emerge as central players in brain disease

Salter, M. W., & Stevens, B. (2017) · Nature Medicine · doi:10.1038/nm.4397 · Cited by 1,767 · see citing works

Resting Microglia Directly Monitor the Functional State of Synapses <i>In Vivo</i> and Determine the Fate of Ischemic Terminals

Wake, H., Moorhouse, A. J., Jinno, S., Kohsaka, S., & Nabekura, J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4363-08.2009 · Cited by 1,619 · see citing works

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

Haynes, S. E., Hollopeter, G., Yang, G., Kurpius, D., Dailey, M. E., Gan, W.-B., & Julius, D. (2006) · Nature Neuroscience · doi:10.1038/nn1805 · Cited by 1,542 · see citing works

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

Zhan, Y., Paolicelli, R. C., Sforazzini, F., Weinhard, L., Bolasco, G., Pagani, F., Vyssotski, A. L., Bifone, A., Gozzi, A., Ragozzino, D., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3641 · Cited by 1,236 · see citing works

Integrin Structure, Activation, and InteractionsPreprint

Campbell, I. D., & Humphries, M. J. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004994 · Cited by 1,192 · see citing works

Electroporation and RNA interference in the rodent retina in vivo and in vitro

Matsuda, T., & Cepko, C. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2235688100 · Cited by 1,032 · see citing works

Weight-conserving characterization of complex functional brain networks

Rubinov, M., & Sporns, O. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.03.069 · Cited by 871 · see citing works

A new pathway for mitochondrial quality control: Mitochondrial-derived vesicles

Sugiura, A., McLelland, G., Fon, E. A., & McBride, H. M. (2014) · The EMBO Journal · doi:10.15252/embj.201488104 · Cited by 862 · see citing works

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

Weinhard, L., di Bartolomei, G., Bolasco, G., Machado, P., Schieber, N. L., Neniskyte, U., Exiga, M., Vadisiute, A., Raggioli, A., Schertel, A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03566-5 · Cited by 790 · see citing works

Layer V cortical neurons require microglial support for survival during postnatal development

Ueno, M., Fujita, Y., Tanaka, T., Nakamura, Y., Kikuta, J., Ishii, M., & Yamashita, T. (2013) · Nature Neuroscience · doi:10.1038/nn.3358 · Cited by 781 · see citing works

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

Soubannier, V., McLelland, G., Zunino, R., Braschi, E., Rippstein, P. U., Fon, E. A., & McBride, H. M. (2012) · Current Biology · doi:10.1016/j.cub.2011.11.057 · Cited by 755 · see citing works

Superresolution Imaging of Chemical Synapses in the Brain

Dani, A., Huang, B., Bergan, J. F., Dulac, C. G., & Zhuang, X. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.021 · Cited by 718 · see citing works

Microglia: Dynamic Mediators of Synapse Development and Plasticity

Wu, Y., Dissing-Olesen, L., MacVicar, B. A., & Stevens, B. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.08.008 · Cited by 661 · see citing works

Endoplasmic reticulum-mitochondrial contactology: structure and signaling functions

Csordás, G., Weaver, D., & Hajnóczky, G. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.02.009 · Cited by 625 · see citing works

Functional assessments in the rodent stroke model

Schaar, K., Brenneman, M. M., & Savitz, S. I. (2010) · Experimental & Translational Stroke Medicine · doi:10.1186/2040-7378-2-13 · Cited by 596 · see citing works

Mitochondria as signaling organelles

Chandel, N. S. (2014) · BMC Biology · doi:10.1186/1741-7007-12-34 · Cited by 576 · see citing works

Thy1-GCaMP6 transgenic mice for neuronal population imaging in vivo

Dana, H., Chen, T.-W., Hu, A., Shields, B. C., Guo, C., Looger, L. L., Kim, D. S., & Svoboda, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108697 · Cited by 574 · see citing works

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

Szalay, G., Martinecz, B., Lénárt, N., Környei, Z., Orsolits, B., Judák, L., Császár, E., Fekete, R., West, B. L., Katona, G., et al. (2016) · Nature Communications · doi:10.1038/ncomms11499 · Cited by 573 · see citing works

Identifying the brain's most globally connected regions

Cole, M. W., Pathak, S., & Schneider, W. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.001 · Cited by 557 · see citing works

Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo

Li, Y., Du, X.-F., Liu, C., Wen, Z., & Du, J. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.10.027 · Cited by 553 · see citing works

Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture

Misgeld, T., & Schwarz, T. L. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.055 · Cited by 546 · see citing works

Regulation of ion channel localization and phosphorylation by neuronal activity

Misonou, H., Mohapatra, D. P., Park, E. W., Leung, V. C. M., Zhen, D., Misonou, K., Anderson, A. E., & Trimmer, J. S. (2004) · Nature Neuroscience · doi:10.1038/nn1260 · Cited by 464 · see citing works

Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1

Madry, C., Kyrargyri, V., Arancibia-Cárcamo, I. L., Jolivet, R., Kohsaka, S., Bryan, R. M., & Attwell, D. (2018) · Neuron · doi:10.1016/j.neuron.2017.12.002 · Cited by 464 · see citing works

Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing

Hall, C. N., Klein-Flugge, M. C., Howarth, C., & Attwell, D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0026-12.2012 · Cited by 451 · see citing works

Migration and differentiation of neural precursor cells can be directed by microglia

Aarum, J., Sandberg, K., Haeberlein, S. L. B., & Persson, M. A. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2237050100 · Cited by 450 · see citing works

Microglia and early brain development: An intimate journey

Thion, M. S., Ginhoux, F., & Garel, S. (2018) · Science · doi:10.1126/science.aat0474 · Cited by 440 · see citing works

Brain microglia constitutively express β-2 integrins

Akiyama, H., & McGeer, P. L. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90055-r · Cited by 430 · see citing works

Mitochondria: from cell death executioners to regulators of cell differentiation

Kasahara, A., & Scorrano, L. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.08.005 · Cited by 420 · see citing works

Mitochondrial quality control: a matter of life and death for neurons

Rugarli, E. I., & Langer, T. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.38 · Cited by 419 · see citing works

Mitochondrial calcium transport: mechanisms and functions

Gunter, T. E., Buntinas, L., Sparagna, G. C., Eliseev, R. A., & Gunter, K. K. (2000) · Cell Calcium · doi:10.1054/ceca.2000.0168 · Cited by 378 · see citing works

Neuronal somatic ATP release triggers neuron–satellite glial cell communication in dorsal root ganglia

Zhang, X., Chen, Y., Wang, C., & Huang, L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611048104 · Cited by 353 · see citing works

Mitochondria—Judges and Executioners of Cell Death Sentences

Bhola, P. D., & Letai, A. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.02.019 · Cited by 326 · see citing works

Prolonged Persistence of Substantial Volumes of Potentially Viable Brain Tissue After Stroke

Marchal, G., Beaudouin, V., Rioux, P. P., Sayette, V. D. L., Doze, F. L., Viader, F., Derlon, J. M., & Baron, J. (1996) · Stroke · doi:10.1161/01.str.27.4.599 · Cited by 324 · see citing works

Mitochondrial Ion Channels

O'Rourke, B. P. (2006) · Annual Review of Physiology · doi:10.1146/annurev.physiol.69.031905.163804 · Cited by 311 · see citing works

The identity and function of microglia in neurodegeneration

Song, W. M., & Colonna, M. (2018) · Nature Immunology · doi:10.1038/s41590-018-0212-1 · Cited by 308 · see citing works

Mitochondrial involvement in psychiatric disorders

Shao, L., Martin, M. V., Watson, S. J., Schatzberg, A. F., Akil, H., Myers, R., Jones, E. G., Bunney, W. E., & Vawter, M. P. (2008) · Annals of Medicine · doi:10.1080/07853890801923753 · Cited by 303 · see citing works

Preferential Origin and Layer Destination of GAD65-GFP Cortical Interneurons

López‐Bendito, G. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh072 · Cited by 288 · see citing works

In VivoLabeling of Parvalbumin-Positive Interneurons and Analysis of Electrical Coupling in Identified Neurons

Meyer, A. H., Katona, I., Blatow, M., Rozov, A. V., & Monyer, H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07055.2002 · Cited by 286 · see citing works

Microglia in steady state

Kierdorf, K., & Prinz, M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci90602 · Cited by 283 · see citing works

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

Dénes, Á., Coutts, G., Lénárt, N., Cruickshank, S. M., Pelegrı́n, P., Skinner, J., Rothwell, N. J., Allan, S. M., & Brough, D. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1419090112 · Cited by 270 · see citing works

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

McLelland, G., Lee, S., McBride, H. M., & Fon, E. A. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201603105 · Cited by 253 · see citing works

Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis

Sierra, A., Beccari, S., Díaz‐Aparicio, I., Encinas, J. M., Comeau, S., & Tremblay, M. (2014) · Neural Plasticity · doi:10.1155/2014/610343 · Cited by 249 · see citing works

Mitochondria in innate immunity

Arnoult, D., Soares, F., Tattoli, I., & Girardin, S. E. (2011) · EMBO Reports · doi:10.1038/embor.2011.157 · Cited by 246 · see citing works

Improved Orange and Red Ca2+ Indicators and Photophysical Considerations for Optogenetic Applications

Wu, J., Liu, L., Matsuda, T., Zhao, Y., Rebane, A. K., Drobizhev, M. A., Chang, Y.-F., Araki, S., Arai, Y., March, K., et al. (2013) · ACS Chemical Neuroscience · doi:10.1021/cn400012b · Cited by 234 · see citing works

The Tom Core Complex

Ahting, U., Thun, C., Hegerl, R., Typke, D., Nargang, F. E., Neupert, W., & Nußberger, S. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.5.959 · Cited by 228 · see citing works

Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling

Dudok, B., Barna, L., Ledri, M., Szabó, S. I., Szabadits, E., Pintér, B., Woodhams, S. G., Henstridge, C. M., Balla, G. Y., Nyilas, R., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3892 · Cited by 227 · see citing works

Distribution of CaMKIIα expression in the brain in vivo, studied by CaMKIIα-GFP mice

Wang, X., Zhang, C., Szabó, G., & Sun, Q. (2013) · Brain Research · doi:10.1016/j.brainres.2013.04.042 · Cited by 206 · see citing works

Mitochondria-associated membranes as hubs for neurodegeneration

Krols, M., Isterdael, G. V., Asselbergh, B., Kremer, A., Lippens, S., Timmerman, V., & Janssens, S. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1528-7 · Cited by 200 · see citing works

Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells

Bantug, G. R., Fischer, M., Grählert, J., Balmer, M. L., Unterstab, G., Develioglu, L., Steiner, R., Zhang, L., Costa, A. S. H., Gubser, P. M., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.02.012 · Cited by 191 · see citing works

Calcium- and Metabolic State-Dependent Modulation of the Voltage-Dependent Kv2.1 Channel Regulates Neuronal Excitability in Response to Ischemia

Misonou, H., Mohapatra, D. P., Menegola, M., et al. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3370-05.2005 · Cited by 190 · see citing works

Mitochondria, calcium-dependent neuronal death and neurodegenerative disease

Duchen, M. R. (2012) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-012-1112-0 · Cited by 184 · see citing works

Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

Fekete, R., Cserép, C., Lénárt, N., Tóth, K., Orsolits, B., Martinecz, B., Méhes, E., Szabó, B., Németh, V., Gönci, B., et al. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1885-0 · Cited by 184 · see citing works

Formation of mitochondrial‐derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system

Cadete, V. J. J., Deschênes, S., Cuillerier, A., Brisebois, F., Sugiura, A., Vincent, A. E., Turnbull, D. M., Picard, M. A., McBride, H. M., & Burelle, Y. (2016) · The Journal of Physiology · doi:10.1113/jp272703 · Cited by 176 · see citing works

Microglia and neuronal cell death

Marín‐Teva, J. L., Cuadros, M. Á., Martín‐Oliva, D., & Navascués, J. (2011) · Neuron Glia Biology · doi:10.1017/s1740925x12000014 · Cited by 152 · see citing works

NAD(P)H fluorescence imaging of postsynaptic neuronal activation in murine hippocampal slices

Shuttleworth, C. W., Brennan, A. M., & Connor, J. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03196.2003 · Cited by 151 · see citing works

Compartmentalized Signaling in Neurons: From Cell Biology to Neuroscience

Terenzio, M., Schiavo, G., & Fainzilber, M. (2017) · Neuron · doi:10.1016/j.neuron.2017.10.015 · Cited by 139 · see citing works

Chronic Systemic Infection Exacerbates Ischemic Brain Damage via a CCL5 (Regulated on Activation, Normal T-Cell Expressed and Secreted)-Mediated Proinflammatory Response in Mice

Dénes, Á., Humphreys, N. E., Lane, T. E., Grencis, R. K., & Rothwell, N. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1227-10.2010 · Cited by 129 · see citing works

Microglial Contact Prevents Excess Depolarization and Rescues Neurons from Excitotoxicity

Kato, G., Inada, H., Wake, H., Akiyoshi, R., Miyamoto, A., Eto, K., Ishikawa, T., Moorhouse, A. J., Strassman, A. M., & Nabekura, J. (2016) · eNeuro · doi:10.1523/eneuro.0004-16.2016 · Cited by 128 · see citing works

Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

McColl, B. W., Carswell, H. V. O., McCulloch, J., & Horsburgh, K. J. (2004) · Brain Research · doi:10.1016/j.brainres.2003.10.028 · Cited by 124 · see citing works

Cerebellar microglia are dynamically unique and survey Purkinje neurons <i>in vivo</i>

Stowell, R. D., Wong, E. L., Batchelor, H. N., Mendes, M. S., Lamantia, C. E., Whitelaw, B. S., & Majewska, A. K. (2018) · Developmental Neurobiology · doi:10.1002/dneu.22572 · Cited by 124 · see citing works

Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum–Plasma Membrane Junctions in Mammalian Brain Neurons

Kirmiz, M., Vierra, N. C., Palacio, S., & Trimmer, J. S. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0893-18.2018 · Cited by 122 · see citing works

The Size of the Synaptic Cleft and Distinct Distributions of Filamentous Actin, Ezrin, CD43, and CD45 at Activating and Inhibitory Human NK Cell Immune Synapses,

McCann, F. E., Vanherberghen, B., Eleme, K., et al. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.6.2862 · Cited by 121 · see citing works

Molecular control of local translation in axon development and maintenance

Cioni, J.-M., Koppers, M., & Holt, C. E. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.02.025 · Cited by 120 · see citing works

Cell Death and Survival Through the Endoplasmic Reticulum- Mitochondrial Axis

Bravo, R., Rodriguez, A. E., Kuzmicic, J., Gutiérrez, T., López‐Crisosto, C., Quiroga, C., Díaz‐Elizondo, J., Chiong, M., Gillette, T. G., Rothermel, B. A., et al. (2013) · Current Molecular Medicine · doi:10.2174/156652413804810781 · Cited by 116 · see citing works

Induction of stable ER–plasma-membrane junctions by Kv2.1 potassium channels

Fox, P. D., Haberkorn, C. J., Akin, E. J., et al. (2015) · Journal of Cell Science · doi:10.1242/jcs.166009 · Cited by 113 · see citing works

Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron–glia signaling

Fields, R. D. (2011) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2011.02.009 · Cited by 103 · see citing works

NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function

Brennan, A. M., Connor, J. A., & Shuttleworth, C. W. (2006) · Journal of Cerebral Blood Flow &amp; Metabolism · doi:10.1038/sj.jcbfm.9600292 · Cited by 97 · see citing works

Kv2.1 cell surface clusters are insertion platforms for ion channel delivery to the plasma membrane

Deutsch, E., Weigel, A. V., Akin, E. J., et al. (2012) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-01-0047 · Cited by 97 · see citing works

Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer

Singel, K. L., Grzankowski, K. S., Khan, A., Grimm, M. J., D’Auria, A. C., Morrell, K., Eng, K. H., Hylander, B. L., Mayor, P. C., Emmons, T. R., et al. (2018) · British Journal of Cancer · doi:10.1038/s41416-018-0339-8 · Cited by 95 · see citing works

Endogenous KV channels in human embryonic kidney (HEK-293) cells

Jiang, B., Sun, X., Cao, K., et al. (2002) · Molecular and Cellular Biochemistry · doi:10.1023/a:1019907104763 · Cited by 87 · see citing works

Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling

Moriyama, Y., Hiasa, M., Sakamoto, S., et al. (2017) · Purinergic Signalling · doi:10.1007/s11302-017-9568-1 · Cited by 86 · see citing works

In vivo widefield calcium imaging of the mouse cortex for analysis of network connectivity in health and brain disease

Cramer, J. V., Gesierich, B. G., Roth, S., Dichgans, M., Duering, M., & Liesz, A. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.06.014 · Cited by 75 · see citing works

Correlated confocal and super-resolution imaging by VividSTORM

Barna, L., Dudok, B., Miczán, V., Horváth, A., László, Z. I., & Katona, I. (2015) · Nature Protocols · doi:10.1038/nprot.2016.002 · Cited by 73 · see citing works

Reversible Disruption of Neuronal Mitochondria by Ischemic and Traumatic Injury Revealed by Quantitative Two-Photon Imaging in the Neocortex of Anesthetized Mice

Kislin, M., Sword, J., Fomitcheva, I. V., Croom, D., Pryazhnikov, E., Lihavainen, E., Toptunov, D., Rauvala, H., Ribeiro, A. S., Khiroug, L. S., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1510-16.2016 · Cited by 73 · see citing works

Glutamate Transporters Regulate Extrasynaptic NMDA Receptor Modulation of Kv2.1 Potassium Channels

Mulholland, P. J., Carpenter‐Hyland, E. P., Hearing, M. C., Becker, H. C., Woodward, J. J., & Chandler, L. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2405-08.2008 · Cited by 71 · see citing works

Dynamic regulation of the voltage-gated Kv2.1 potassium channel by multisite phosphorylation

Mohapatra, D. P., Park, K.-S., & Trimmer, J. S. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351064 · Cited by 69 · see citing works

Vesicular expression and release of ATP from dopaminergic neurons of the mouse retina and midbrain

Ho, T., Jobling, A. I., Greferath, U., et al. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00389 · Cited by 57 · see citing works

Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases

Joshi, A. U., & Mochly‐Rosen, D. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.08.010 · Cited by 57 · see citing works

Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility

Rieusset, J. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.06.097 · Cited by 47 · see citing works

Voltage‐gated Potassium Channel as a Facilitator of Exocytosis

Feinshreiber, L., Singer‐Lahat, D., Ashery, U., et al. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2008.03997.x · Cited by 45 · see citing works

Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

Orsini, F., Fumagalli, S., Császár, E., Tóth, K., Blasio, D. D., Zangari, R., Lénárt, N., Dénes, Á., & Simoni, M. G. D. (2018) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311058 · Cited by 40 · see citing works

Contribution of platelet P2Y12 receptors to chronic Complete Freund's adjuvant‐induced inflammatory pain

Bekő, K., Koványi, B., Gölöncsér, F., Horváth, G., Dénes, Á., Környei, Z., Botz, B., Helyes, Z., Müller, C. E., & Sperlágh, B. (2017) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13684 · Cited by 36 · see citing works

For how long is brain tissue salvageable? Imaging-based evidence

Baron, J., & Moseley, M. E. (2000) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1053/jscd.2000.18910 · Cited by 24 · see citing works

Specific Temporal Distribution and Subcellular Localization of a Functional Vesicular Nucleotide Transporter (VNUT) in Cerebellar Granule Neurons

Menéndez‐Méndez, A., Díaz‐Hernandéz, J. I., Ortega, F., Gualix, J., Gómez‐Villafuertes, R., & Miras‐Portugal, M. T. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00951 · Cited by 18 · see citing works

Erratum: Experience-dependent structural synaptic plasticity in the mammalian brain

Holtmaat, A. J. D. G., & Svoboda, K. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2721 · Cited by 14 · see citing works

Bioenergetic and volume regulatory effects of mitoKATP channel modulators protect against hypoxia-reoxygenation induced mitochondrial dysfunction

Onukwufor, J. O., Stevens, D., & Kamunde, C. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.140186 · Cited by 8 · see citing works

Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

Gao, C., Jiang, J., Tan, Y., & Chen, S. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01588-0 · Cited by 1,616 · see citing works

Synergy between amyloid-β and tau in Alzheimer’s disease

Busche, M. A., & Hyman, B. T. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0687-6 · Cited by 1,242 · see citing works

The Semantics of Microglia Activation: Neuroinflammation, Homeostasis, and Stress

Woodburn, S. C., Bollinger, J. L., & Wohleb, E. S. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02309-6 · Cited by 783 · see citing works

Microglia and Central Nervous System–Associated Macrophages—From Origin to Disease Modulation

Prinz, M., Masuda, T., Wheeler, M. A., & Quintana, F. J. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-093019-110159 · Cited by 584 · see citing works

Microglia modulate neurodegeneration in Alzheimer’s and Parkinson’s diseases

Bartels, T., De Schepper, S., & Hong, S. (2020) · Science · doi:10.1126/science.abb8587 · Cited by 412 · see citing works

Microglia: Agents of the CNS Pro-Inflammatory Response

Rodríguez-Gómez, J. A., Kavanagh, E., Engskog-Vlachos, P., Engskog, M. K. R., Herrera, A. J., Espinosa-Oliva, A. M., Joseph, B., Hajji, N., Venero, J. L., & Burguillos, M. A. (2020) · Cells · doi:10.3390/cells9071717 · Cited by 365 · see citing works

Microglia Phenotypes in Aging and Neurodegenerative Diseases

Wendimu, M. Y., & Hooks, S. B. (2022) · Cells · doi:10.3390/cells11132091 · Cited by 336 · see citing works

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Scannail, A. N., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., et al. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.07.005 · Cited by 316 · see citing works

Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

De Schepper, S., Ge, J. Z., Sierksma, A., Crowley, G., Ferreira, L. S. S., Garceau, D., Toomey, C. E., Sokolova, D., Rueda-Carrasco, J., Shin, S.-H., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01257-z · Cited by 295 · see citing works

Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions

Cserép, C., Pósfai, B., & Dénes, Á. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.007 · Cited by 256 · see citing works

Microglia and Neuroinflammation: Crucial Pathological Mechanisms in Traumatic Brain Injury-Induced Neurodegeneration

Shao, F., Wang, X., Wu, H., Wu, Q., & Zhang, J. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.825086 · Cited by 250 · see citing works

How microglia sense and regulate neuronal activity

Umpierre, A. D., & Wu, L. (2021) · Glia · doi:10.1002/glia.23961 · Cited by 237 · see citing works

Microglia and Neuroinflammation: What Place for P2RY12?

Gómez Morillas, A., Besson, V. C., & Lerouet, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041636 · Cited by 214 · see citing works

Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

Scheiblich, H., Eikens, F., Wischhof, L., Opitz, S., Jüngling, K., Cserép, C., Schmidt, S. V., Lambertz, J., Bellande, T., Pósfai, B., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.06.029 · Cited by 207 · see citing works

The Emerging Role of Central and Peripheral Immune Systems in Neurodegenerative Diseases

Zang, X., Chen, S., Zhu, J., Ma, J., & Zhai, Y. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.872134 · Cited by 139 · see citing works

Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain

Welikovitch, L. A., Do Carmo, S., Maglóczky, Z., Malcolm, J. C., Lőke, J., Klein, W. L., Freund, T., & Cuello, A. C. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1914593117 · Cited by 116 · see citing works

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

van Olst, L., Rodriguez-Mogeda, C., Picon, C., Kiljan, S., James, R. E., Kamermans, A., van der Pol, S. M. A., Knoop, L., Michailidou, I., Drost, E., et al. (2021) · Acta Neuropathologica · doi:10.1007/s00401-021-02293-4 · Cited by 87 · see citing works

Role of P2X7 Receptors in Immune Responses During Neurodegeneration

Oliveira-Giacomelli, Á., Petiz, L. L., Andrejew, R., Turrini, N., Silva, J. B., Sack, U., & Ulrich, H. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.662935 · Cited by 68 · see citing works

Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain

Kiss, T., Nyúl-Tóth, Á., DelFavero, J., Balasubramanian, P., Tarantini, S., Faakye, J., Gulej, R., Ahire, C., Ungvari, A., Yabluchanskiy, A., et al. (2022) · GeroScience · doi:10.1007/s11357-022-00521-7 · Cited by 66 · see citing works

Microglia Dystrophy Following Binge-Like Alcohol Exposure in Adolescent and Adult Male Rats

Marshall, S. A., McClain, J. A., Wooden, J. I., & Nixon, K. (2020) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2020.00052 · Cited by 51 · see citing works

Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing

Manabe, T., Rácz, I., Schwartz, S., Oberle, L., Santarelli, F., Emmrich, J. V., Neher, J. J., & Heneka, M. T. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15491 · Cited by 44 · see citing works

Microglia: Activity‐dependent regulators of neural circuits

Durán Laforet, V., & Schafer, D. P. (2024) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15105 · Cited by 32 · see citing works

Roles of Microglia in Synaptogenesis, Synaptic Pruning, and Synaptic Plasticity in Physiological Conditions and Central Nervous System Disorders

Xie, M., Wang, T., Feng, J., Ma, D., Feng, L., & Hao, Y. (2025) · Current Neuropharmacology · doi:10.2174/1570159x23666250225091729 · Cited by 7 · see citing works

Bone marrow-derived myeloid cells transiently colonize the brain during postnatal development and interact with glutamatergic synapses

Carrier, M., Robert, M.-È., St-Pierre, M.-K., Ibáñez, F. G., Gonçalves de Andrade, E., Laroche, A., Picard, K., Vecchiarelli, H. A., Savage, J. C., Boilard, É., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110037 · Cited by 5 · see citing works

The impact of commercially available purinergic ligands on purinergic signalling research

Flanaghan, J. R., & Roome, S. J. (2011) · Purinergic Signalling · doi:10.1007/s11302-011-9269-0

Purinergic signaling in schistosomal infection

Silva, C. L. M. (2016) · Biomedical Journal · doi:10.1016/j.bj.2016.06.006 · Cited by 16 · see citing works

Extracellular nucleotides and nucleosides : release, receptors, and physiological and pathophysiological effects

Schwiebert, E. M. (2003) · Cited by 17 · see citing works

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

Beaino, W., Janssen, B., Kooij, G., van der Pol, S. M. A., Hof, B. V. H., van Horssen, J., Windhorst, A. D., & de Vries, H. E. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-1034-z · Cited by 141 · see citing works

Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future

Burnstock, G. (2012) · BioEssays · doi:10.1002/bies.201100130 · Cited by 209 · see citing works