Grummt, Ingrid

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

Ford, E., Voit, R., Liszt, G., Magin, C., Grummt, I., & Guarente, L. (2006) · Genes & Development

Sirtuins and Resveratrol in MedicineNuclear Structure and Function

Cited by 629

Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases

Mayer, C., & Grummt, I. (2006) · Oncogene

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

Cited by 568

Life on a planet of its own: Regulation of RNA polymerase I transcription in the nucleolus

Grummt, I. (2003) · Genes & Development

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 540

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

Santoro, R., Li, J., & Grummt, I. (2002) · Nature Genetics

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 406

Cellular stress and nucleolar function

Mayer, C., & Grummt, I. (2005) · Cell Cycle

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 233

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

Hoppe, S., Bierhoff, H., Cado, I., Weber, A., Tiebe, M., Grummt, I., & Voit, R. (2009) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerGenomics and Chromatin Dynamics

Cited by 225

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

Guetg, C., Lienemann, P., Sirri, V., Grummt, I., Hernandez‐Verdun, D., Hottiger, M. O., Fussenegger, M., & Santoro, R. (2010) · The EMBO Journal

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 184

Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing

Bierhoff, H., Dammert, M. A., Brocks, D., Dambacher, S., Schotta, G., & Grummt, I. (2014) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 179

The chromatin remodelling complex WSTF–SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription

Percipalle, P., Fomproix, N., Cavellán, E., Voit, R., Reimer, G., Krüger, T., Thyberg, J., Scheer, U., Grummt, I., & Östlund Farrants, A. (2006) · The EMBO Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 171

p53 represses ribosomal gene transcription

Budde, A., & Grummt, I. (1999) · Oncogene

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 157

Epigenetic control of RNA polymerase I transcription in mammalian cells

Grummt, I., & Längst, G. (2013) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 132

The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions

Xie, W., Ling, T., Zhou, Y., Feng, W., Zhu, Q., Stunnenberg, H. G., Grummt, I., & Tao, W. (2012) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 124

The seven faces of SIRT7

Blank, M. F., & Grummt, I. (2017) · Transcription

Sirtuins and Resveratrol in MedicineHistone Deacetylase Inhibitors Research

Cited by 111

NuRD Blocks Reprogramming of Mouse Somatic Cells into Pluripotent Stem Cells

Luo, M., Ling, T., Xie, W., Sun, H., Zhou, Y., Zhu, Q., Shen, M., Zong, L., Lyu, G., Zhao, Y., et al. (2013) · Stem Cells

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 104

A model for the topology of active ribosomal RNA genes

Denissov, S., Lessard, F., Mayer, C., Stefanovsky, V., van Driel, M., Grummt, I., Moss, T., & Stunnenberg, H. G. (2011) · The EMBO Reports

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 58