Halder, Georg

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007) · Genes & Development

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 3,092

Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila

Halder, G., Callaerts, P., & Gehring, W. J. (1995) · Science

Developmental Biology and Gene RegulationOcular Disorders and Treatments

Cited by 1,573

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

Halder, G., Dupont, S., & Piccolo, S. (2012) · Nature Reviews Molecular Cell Biology

Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions

Cited by 985

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

Moya, I. M., & Halder, G. (2019) · Nature Reviews Molecular Cell Biology

Hippo pathway signaling and YAP/TAZCongenital heart defects research

Cited by 981

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

Udan, R. S., Kango-Singh, M., Nolo, R., Tao, C., & Halder, G. (2003) · Nature Cell Biology

Hippo pathway signaling and YAP/TAZCancer-related Molecular Pathways

Cited by 747

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Verfaillie, A., Imrichova, H., Atak, Z. K., Dewaele, M., Rambow, F., Hulselmans, G., Christiaens, V., Svetlichnyy, D., Luciani, F., Van den Mooter, L., et al. (2015) · Nature Communications

Melanoma and MAPK PathwaysGenomics and Chromatin Dynamics

Cited by 489

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Mannaerts, I., Leite, S. B., Verhulst, S., Claerhout, S., Eysackers, N., Thoen, L. F. R., Hoorens, A., Reynaert, H., Halder, G., & van Grunsven, L. A. (2015) · Journal of Hepatology

Liver physiology and pathologyHippo pathway signaling and YAP/TAZ

Cited by 410

Tumor suppression by cell competition through regulation of the Hippo pathway

Chen, C.-L., Schroeder, M. C., Kango-Singh, M., Tao, C., & Halder, G. (2012) · Proceedings of the National Academy of Sciences

Hippo pathway signaling and YAP/TAZDevelopmental Biology and Gene Regulation

Cited by 187

The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Jacobs, J., Atkins, M., Davie, K., Imrichova, H., Romanelli, L., Christiaens, V., Hulselmans, G., Potier, D., Wouters, J., Taskiran, I. I., et al. (2018) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 155

An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

Atkins, M., Potier, D., Romanelli, L., Jacobs, J., Mach, J., Hamaratoglu, F., Aerts, S., & Halder, G. (2016) · Current Biology

Hippo pathway signaling and YAP/TAZGene Regulatory Network Analysis

Cited by 88

Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

Verboven, E., Moya, I. M., Sansores-Garcia, L., Xie, J., Hillen, H., Kowalczyk, W., Vella, G., Verhulst, S., Castaldo, S. A., Algueró-Nadal, A., et al. (2021) · Gastroenterology

Liver physiology and pathologyHippo pathway signaling and YAP/TAZ

Cited by 87

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation

Bravo González-Blas, C., Matetovici, I., Hillen, H., Taskiran, I. I., Vandepoel, R., Christiaens, V., Sansores-García, L., Verboven, E., Hulselmans, G., Poovathingal, S., et al. (2024) · Nature Cell Biology

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 85

Initiation of hepatic stellate cell activation extends into chronic liver disease

De Smet, V., Eysackers, N., Merens, V., Kazemzadeh Dastjerd, M., Halder, G., Verhulst, S., Mannaerts, I., & van Grunsven, L. A. (2021) · Cell Death & Disease

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 78

Highly conserved gene order and numerous novel repetitive elements in genomic regions linked to wing pattern variation in Heliconius butterflies

Papa, R., Morrison, C. M., Walters, J. R., Counterman, B. A., Chen, R., Halder, G., Ferguson, L., Chamberlain, N., ffrench-Constant, R., Kapan, D. D., et al. (2008) · BMC Genomics

Lepidoptera: Biology and TaxonomyChromosomal and Genetic Variations

Cited by 50

Shared enhancer gene regulatory networks between wound and oncogenic programs

Floc'hlay, S., Balaji, R., Stanković, D., Christiaens, V. M., Bravo González-Blas, C., De Winter, S., Hulselmans, G. J., De Waegeneer, M., Quan, X., Koldere, D., et al. (2023) · eLife

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 27

Enhancer grammar of liver cell types and hepatocyte zonation states

González-Blas, C. B., Matetovici, I., Hillen, H., Taskiran, I. I., Vandepoel, R., Christiaens, V., Sansores-García, L., Verboven, E., Hulselmans, G., Poovathingal, S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 5