Valent, Peter

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Zuber, J., Shi, J., Wang, E., Rappaport, A. R., Herrmann, H., Sison, E. A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., et al. (2011) · Nature

Protein Degradation and InhibitorsAcute Myeloid Leukemia Research

Cited by 1,870

Molecular International Prognostic Scoring System for Myelodysplastic Syndromes

Bernard, E., Tuechler, H., Greenberg, P. L., Hasserjian, R. P., Arango Ossa, J. E., Nannya, Y., Devlin, S. M., Creignou, M., Pinel, P., Monnier, L., et al. (2022) · NEJM Evidence

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 867

Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria

Valent, P., Akin, C., Escribano, L., Födinger, M., Hartmann, K., Brockow, K., Castells, M., Sperr, W. R., Kluin‐Nelemans, H. C., Hamdy, N. A. T., et al. (2007) · European Journal of Clinical Investigation

Mast cells and histamineEosinophilic Disorders and Syndromes

Cited by 750

Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal

Valent, P., Akin, C., Arock, M., Brockow, K., Butterfield, J. H., Carter, M. C., Castells, M., Escribano, L., Hartmann, K., Lieberman, P., et al. (2012) · International Archives of Allergy and Immunology

Mast cells and histamineAsthma and respiratory diseases

Cited by 654

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Bernard, E., Nannya, Y., Hasserjian, R. P., Devlin, S. M., Tuechler, H., Medina-Martinez, J. S., Yoshizato, T., Shiozawa, Y., Saiki, R., Malcovati, L., et al. (2020) · Nature Medicine

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

Cited by 648

Mast Cells, Mastocytosis, and Related Disorders

Theoharides, T. C., Valent, P., & Akin, C. (2015) · New England Journal of Medicine

Mast cells and histamineGastrointestinal Tumor Research and Treatment

Cited by 518

Anemia at older age: etiologies, clinical implications, and management

Stauder, R., Valent, P., & Theurl, I. (2018) · Blood

Hematological disorders and diagnosticsErythropoietin and Anemia Treatment

Cited by 479

Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell Factor/kit-ligand in long-term culture

Valent, P., Spanblochl, E., Sperr, W., Sillaber, C., Zsebo, K., Agis, H., Strobl, H., Geissler, K., Bettelheim, P., & Lechner, K. (1992) · Blood

Mast cells and histamineAsthma and respiratory diseases

Cited by 439

Mast cell activation syndrome: Proposed diagnostic criteria

Akin, C., Valent, P., & Metcalfe, D. D. (2010) · Journal of Allergy and Clinical Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 327

Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal

Valent, P., Akin, C., Hartmann, K., Alvarez-Twose, I., Brockow, K., Hermine, O., Niedoszytko, M., Schwaab, J., Lyons, J. J., Carter, M. C., et al. (2021) · HemaSphere

Mast cells and histamineGastrointestinal Tumor Research and Treatment

Cited by 317

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Hogg, S. J., Vervoort, S. J., Deswal, S., Ott, C. J., Li, J., Cluse, L. A., Beavis, P. A., Darcy, P. K., Martin, B. P., Spencer, A., et al. (2017) · Cell Reports

Protein Degradation and InhibitorsCancer Immunotherapy and Biomarkers

Cited by 308

KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis

Arock, M., Sotlar, K., Akin, C., Broesby-Olsen, S., Hoermann, G., Escribano, L., Kristensen, T. K., Kluin-Nelemans, H. C., Hermine, O., Dubreuil, P., et al. (2015) · Leukemia

Mast cells and histamineGastrointestinal Tumor Research and Treatment

Cited by 290

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Hantschel, O., Rix, U., Schmidt, U., Bürckstümmer, T., Kneidinger, M., Schütze, G., Colinge, J., Bennett, K. L., Ellmeier, W., Valent, P., et al. (2007) · Proceedings of the National Academy of Sciences

Chronic Myeloid Leukemia TreatmentsMast cells and histamine

Cited by 284

The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis

Bühring, H.-J., Streble, A., & Valent, P. (2004) · International Archives of Allergy and Immunology

Mast cells and histamineAllergic Rhinitis and Sensitization

Cited by 231

Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome

Valent, P., Akin, C., Bonadonna, P., Hartmann, K., Brockow, K., Niedoszytko, M., Nedoszytko, B., Siebenhaar, F., Sperr, W. R., Oude Elberink, J. N. G., et al. (2019) · The Journal of Allergy and Clinical Immunology: In Practice

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 225

Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia

Herrmann, H., Sadovnik, I., Cerny-Reiterer, S., Rülicke, T., Stefanzl, G., Willmann, M., Hoermann, G., Bilban, M., Blatt, K., Herndlhofer, S., et al. (2014) · Blood

Chronic Myeloid Leukemia TreatmentsAcute Myeloid Leukemia Research

Cited by 223

Serum tryptase levels in patients with mastocytosis: Correlation with mast cell burden and implication for defining the category of disease

Sperr, W. R., Jordan, J.-H., Fiegl, M., Escribano, L., Bellas, C., Dirnhofer, S., Semper, H., Simonitsch-Klupp, I., Horny, H.-P., & Valent, P. (2002) · International Archives of Allergy and Immunology

Mast cells and histamineEosinophilic Disorders and Syndromes

Cited by 207

Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Kornauth, C., Pemovska, T., Vladimer, G. I., Bayer, G., Bergmann, M., Eder, S., Eichner, R., Erl, M., Esterbauer, H., Exner, R., et al. (2022) · Cancer Discovery

Acute Myeloid Leukemia ResearchChronic Lymphocytic Leukemia Research

Cited by 206

Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis

Greiner, G., Sprinzl, B., Górska, A., Ratzinger, F., Gurbisz, M., Witzeneder, N., Schmetterer, K. G., Gisslinger, B., Uyanik, G., Hadzijusufovic, E., et al. (2021) · Blood

Mast cells and histamineGastrointestinal Tumor Research and Treatment

Cited by 189

Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis

Valent, P., Escribano, L., Broesby‐Olsen, S., Hartmann, K., Grattan, C., Brockow, K., Niedoszytko, M., Nedoszytko, B., Oude Elberink, J. N. G., Kristensen, T., et al. (2014) · Allergy

Mast cells and histamineGastrointestinal Tumor Research and Treatment

Cited by 174

Recombinant allergens promote expression of CD203c on basophils in sensitized individuals

Hauswirth, A. W., Natter, S., Ghannadan, M., Majlesi, Y., Schernthaner, G.-H., Sperr, W. R., Bühring, H.-J., Valenta, R., & Valent, P. (2002) · Journal of Allergy and Clinical Immunology

Allergic Rhinitis and SensitizationMast cells and histamine

Cited by 169

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Porpaczy, E., Tripolt, S., Hoelbl-Kovacic, A., Gisslinger, B., Bago-Horvath, Z., Casanova-Hevia, E., Clappier, E., Decker, T., Fajmann, S., Fux, D. A., et al. (2018) · Blood

Myeloproliferative Neoplasms: Diagnosis and TreatmentLymphoma Diagnosis and Treatment

Cited by 151

Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia

Sperr, W. R., Jordan, J.-H., Baghestanian, M., Kiener, H.-P., Samorapoompichit, P., Semper, H., Hauswirth, A., Schernthaner, G.-H., Chott, A., Natter, S., et al. (2001) · Blood

Acute Myeloid Leukemia ResearchMast cells and histamine

Cited by 149

Why the 20% + 2 Tryptase Formula Is a Diagnostic Gold Standard for Severe Systemic Mast Cell Activation and Mast Cell Activation Syndrome

Valent, P., Bonadonna, P., Hartmann, K., Broesby-Olsen, S., Brockow, K., Butterfield, J. H., Triggiani, M., Lyons, J. J., Oude Elberink, J. N. G., Arock, M., et al. (2019) · International Archives of Allergy and Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 146