Cramer, Patrick

RNA velocity of single cells

La Manno, G., Soldatov, R., Zeisel, A., Braun, E., Hochgerner, H., Petukhov, V., Lidschreiber, K., Kastriti, M. E., Lönnerberg, P., Furlan, A., et al. (2018) · Nature

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 4,118

Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution

Cramer, P., Bushnell, D. A., & Kornberg, R. D. (2001) · Science

Genomics and Chromatin DynamicsEnzyme Structure and Function

Cited by 1,247

Structure of activated transcription complex Pol II–DSIF–PAF–SPT6

Vos, S. M., Farnung, L., Boehning, M., Wigge, C., Linden, A., Urlaub, H., & Cramer, P. (2018) · Nature

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 432

Structural basis of RNA polymerase II backtracking, arrest and reactivation

Cheung, A. C. M., & Cramer, P. (2011) · Nature

Genomics and Chromatin DynamicsRNA and protein synthesis mechanisms

Cited by 373

In-cell architecture of an actively transcribing-translating expressome

O’Reilly, F. J., Xue, L., Graziadei, A., Sinn, L., Lenz, S., Tegunov, D., Blötz, C., Singh, N., Hagen, W. J. H., Cramer, P., et al. (2020) · Science

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 284

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function

Dodonova, S. O., Zhu, F., Dienemann, C., Taipale, J., & Cramer, P. (2020) · Nature

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 265

Sequence determinants of human gene regulatory elements

Sahu, B., Hartonen, T., Pihlajamaa, P., Wei, B., Dave, K., Zhu, F., Kaasinen, E., Lidschreiber, K., Lidschreiber, M., Daub, C. O., et al. (2022) · Nature Genetics

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 198

Structural Basis of Mitochondrial Transcription Initiation

Hillen, H. S., Morozov, Y. I., Sarfallah, A., Temiakov, D., & Cramer, P. (2017) · Cell

Genomics and Chromatin DynamicsMitochondrial Function and Pathology

Cited by 192

Visualizing translation dynamics at atomic detail inside a bacterial cell

Xue, L., Lenz, S., Zimmermann-Kogadeeva, M., Tegunov, D., Cramer, P., Bork, P., Rappsilber, J., & Mahamid, J. (2022) · Nature

RNA and protein synthesis mechanismsAdvanced Electron Microscopy Techniques and Applications

Cited by 184

Structural basis of TFIIH activation for nucleotide excision repair

Kokic, G., Chernev, A., Tegunov, D., Dienemann, C., Urlaub, H., & Cramer, P. (2019) · Nature Communications

DNA Repair MechanismsEnzyme Structure and Function

Cited by 163

Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation

Vos, S. M., Farnung, L., Linden, A., Urlaub, H., & Cramer, P. (2020) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 160

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

Baluapuri, A., Hofstetter, J., Dudvarski Stankovic, N., Endres, T., Bhandare, P., Vos, S. M., Adhikari, B., Schwarz, J. D., Narain, A., Vogt, M., et al. (2019) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 138

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

Walmacq, C., Cheung, A. C. M., Kireeva, M. L., Lubkowska, L., Ye, C., Gotte, D., Strathern, J. N., Carell, T., Cramer, P., & Kashlev, M. (2012) · Molecular Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 124

Evidence for additive and synergistic action of mammalian enhancers during cell fate determination

Choi, J., Lysakovskaia, K., Stik, G., Demel, C., Söding, J., Tian, T. V., Graf, T., & Cramer, P. (2021) · eLife

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 117

Structural basis of mitochondrial transcription

Hillen, H. S., Temiakov, D., & Cramer, P. (2018) · Nature Structural & Molecular Biology

Mitochondrial Function and PathologyGenomics and Chromatin Dynamics

Cited by 111

Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding

Wang, H., Farnung, L., Dienemann, C., & Cramer, P. (2020) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 93

Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTAN

Zacher, B., Michel, M., Schwalb, B., Cramer, P., Tresch, A., & Gagneur, J. (2017) · PLOS ONE

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 91

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

van den Heuvel, D., Rodríguez-Martínez, M., van der Meer, P. J., Moreno, N. N., Park, J., Kim, H.-S., van Schie, J. J. M., Wondergem, A. P., D’Souza, A., Yakoub, G., et al. (2024) · Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 45

The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs

Hillen, H. S., Markov, D. A., Wojtas, I. D., Hofmann, K. B., Lidschreiber, M., Cowan, A. T., Jones, J. L., Temiakov, D., Cramer, P., & Anikin, M. (2021) · Proceedings of the National Academy of Sciences

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 21

Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II

Rengachari, S., Schilbach, S., Kaliyappan, T., Gouge, J., Zumer, K., Schwarz, J., Urlaub, H., Dienemann, C., Vannini, A., & Cramer, P. (2022) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 19

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid–protein interaction sites by mass spectrometry

Welp, L. M., Wulf, A., Chernev, A., Horokhovskyi, Y., Moshkovskii, S., Dybkov, O., Neumann, P., Pašen, M., Siraj, A., Raabe, M., et al. (2025) · Nucleic Acids Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 12