Structural basis of RNA polymerase II backtracking, arrest and reactivation

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Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS

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Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in <i>Drosophila</i>

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Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA Cleavage

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A ratchet mechanism of transcription elongation and its control.

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Structural basis for substrate loading in bacterial RNA polymerase

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The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS

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RNA Polymerase Switches between Inactivated and Activated States By Translocating Back and Forth along the DNA and the RNA

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Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation

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Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

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Nature of the Nucleosomal Barrier to RNA Polymerase II

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A Central Role of the RNA Polymerase Trigger Loop in Active-Site Rearrangement during Transcriptional Pausing

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Unified two‐metal mechanism of RNA synthesis and degradation by RNA polymerase

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Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA

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Efficient Release from Promoter-Proximal Stall Sites Requires Transcript Cleavage Factor TFIIS

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The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes

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Organization and regulation of gene transcription

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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulationPreprint

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Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex

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Control of Transcriptional Elongation

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Structural Basis of Transcription Initiation

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Structure of paused transcription complex Pol II–DSIF–NELF

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Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis

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Linking RNA Polymerase Backtracking to Genome Instability in E. coli

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Structural biology of SARS-CoV-2: open the door for novel therapies

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Structural visualization of key steps in human transcription initiation

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The central role of RNA in human development and cognition

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Conflict Resolution in the Genome: How Transcription and Replication Make It Work

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Systematic Identification of Signal-Activated Stochastic Gene Regulation

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Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing

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RNA Polymerase Backtracking in Gene Regulation and Genome Instability

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Causes and consequences of RNA polymerase II stalling during transcript elongation

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Transcription-mediated replication hindrance: a major driver of genome instabilityPreprint

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Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective

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RNA polymerase I structure and transcription regulation

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Structure of transcribing mammalian RNA polymerase II

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Structural basis of the nucleosome transition during RNA polymerase II passage

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RNA polymerase II speed: a key player in controlling and adapting transcriptome composition

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Stochastic resetting in backtrack recovery by RNA polymerases

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Mammalian Transcription-Coupled Excision Repair

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RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing

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Structural Basis for NusA Stabilized Transcriptional Pausing

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Transcribing through the nucleosome

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RNA polymerase II transcription: Structure and mechanism

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Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

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Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage

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The Spt4–Spt5 complex: A multi-faceted regulator of transcription elongation

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A Nexus for Gene Expression—Molecular Mechanisms of Spt5 and NusG in the Three Domains of Life

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Structural Basis of Transcriptional Pausing in Bacteria

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Structural basis of nucleosome transcription mediated by Chd1 and FACT

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Mechanisms of Bacterial Transcription Termination

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Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

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Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism

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Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex

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Structural Insights into the Eukaryotic Transcription Initiation Machinery

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Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

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Dynamics of Pyrophosphate Ion Release and Its Coupled Trigger Loop Motion from Closed to Open State in RNA Polymerase II

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Pause &amp; go: from the discovery of RNA polymerase pausing to its functional implications

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Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases

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Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

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Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5′ Pause Release, Termination, and Transcription Elongation Rate

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Structural Biology of RNA Polymerase II Transcription: 20 Years On

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Nascent RNA structure modulates the transcriptional dynamics of RNA polymerases

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RNA Polymerase II Transcription Elongation Control

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A Movie of RNA Polymerase II Transcription

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Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation

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Structural Basis of RNA Polymerase I Transcription Initiation

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Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states

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Transcription-Coupled DNA Repair: From Mechanism to Human Disorder

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The fate of the messenger is pre-determined: A new model for regulation of gene expression

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Intragenic Enhancers Attenuate Host Gene Expression

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Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble

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Structural basis of transcription elongation

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Histone exchange and histone modifications during transcription and aging

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Structural basis of initial RNA polymerase II transcription

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Bridge helix bending promotes RNA polymerase II backtracking through a critical and conserved threonine residue

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Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

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Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin

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The RNA exosome promotes transcription termination of backtracked RNA polymerase II

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The conflict between DNA replication and transcription

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