Fruttiger, Marcus

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D., et al. (2003) · The Journal of Cell Biology

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

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A foundation model for generalizable disease detection from retinal images

Zhou, Y., Chia, M. A., Wagner, S. K., Ayhan, M. S., Williamson, D. J., Struyven, R. R., Liu, T., Xu, M., Lozano, M. G., Woodward-Court, P., et al. (2023) · Nature

Retinal Imaging and AnalysisOphthalmology and Visual Health Research

Cited by 1,014

Wnt/β-catenin signaling controls development of the blood–brain barrier

Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C. J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., et al. (2008) · The Journal of Cell Biology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 860

FOXO1 couples metabolic activity and growth state in the vascular endothelium

Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M. F., Lim, R., Zimmermann, B., Aspalter, I. M., Franco, C. A., Boettger, T., et al. (2016) · Nature

FOXO transcription factor regulationAngiogenesis and VEGF in Cancer

Cited by 579

Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination

Woodruff, R. H., Fruttiger, M., Richardson, W. D., & Franklin, R. J. M. (2004) · Molecular and Cellular Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 335

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C. A., Murtomäki, A., Aranda, E., et al. (2011) · Nature Cell Biology

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 321

Essential Regulation of CNS Angiogenesis by the Orphan G Protein–Coupled Receptor GPR124

Kuhnert, F., Mancuso, M. R., Shamloo, A., Wang, H.-T., Choksi, V., Florek, M., Su, H., Fruttiger, M., Young, W. L., Heilshorn, S. C., et al. (2010) · Science

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 301

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

Reis, M., Czupalla, C. J., Ziegler, N., Devraj, K., Zinke, J., Seidel, S., Heck, R., Thom, S., Macas, J., Bockamp, E., et al. (2012) · Journal of Experimental Medicine

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 167

Platelet-Derived Growth Factor Promotes Repair of Chronically Demyelinated White Matter

Vana, A. C., Flint, N. C., Harwood, N. E., Le, T. Q., Fruttiger, M., & Armstrong, R. C. (2007) · Journal of Neuropathology & Experimental Neurology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 101

Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors

Longbottom, R., Fruttiger, M., Douglas, R. H., Martinez-Barbera, J. P., Greenwood, J., & Moss, S. E. (2009) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 85

Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not from axons

Fruttiger, M., Calver, A. R., & Richardson, W. D. (2000) · Current Biology

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

Cited by 81

Expression of Neonatal Fc Receptor in the Eye

Powner, M. B., McKenzie, J. A. G., Christianson, G. J., Roopenian, D. C., & Fruttiger, M. (2014) · Investigative Opthalmology & Visual Science

Monoclonal and Polyclonal Antibodies ResearchRetinal Diseases and Treatments

Cited by 62

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia

Tideman, J. W. L., Pärssinen, O., Haarman, A. E. G., Khawaja, A. P., Wedenoja, J., Williams, K. M., Biino, G., Ding, X., Kähönen, M., Lehtimäki, T., et al. (2021) · JAMA Ophthalmology

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 56

Retinal Asymmetry in Multiple Sclerosis

Petzold, A., Chua, S. Y. L., Khawaja, A. P., Keane, P. A., Khaw, P. T., Reisman, C., Dhillon, B., Strouthidis, N. G., Foster, P. J., Patel, P. J., et al. (2021) · Brain

Multiple Sclerosis Research StudiesGlaucoma and retinal disorders

Cited by 56

Diverse functions of retinoic acid in brain vascular development.

Bonney, S., Harrison-Uy, S., Mishra, S., MacPherson, A. M., Choe, Y., Li, D., Jaminet, S.-C., Fruttiger, M., Pleasure, S. J., & Siegenthaler, J. A. (2016) · Journal of Neuroscience

Barrier Structure and Function StudiesAngiogenesis and VEGF in Cancer

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