Xu, Huaxi

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

Zheng, H., Liu, C.-C., Atagi, Y., Chen, X.-F., Jia, L., Yang, L., He, W., Zhang, X., Kang, S. S., Rosenberry, T. L., et al. (2016) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

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Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

Zhao, Y., Tseng, I.-C., Heyser, C. J., Rockenstein, E., Mante, M., Adame, A., Zheng, Q., Huang, T., Wang, X., Arslan, P. E., et al. (2015) · Neuron

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

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Trisomy 21–induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25

Zheng, Q., Li, G., Wang, S., Zhou, Y., Liu, K., Gao, Y., Zhou, Y., Zheng, L., Zhu, L., Deng, Q., et al. (2021) · Science Advances

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity

Wang, X., Huang, T., Zhao, Y., Zheng, Q., Thompson, R. C., Bu, G., Zhang, Y.-W., Hong, W., & Xu, H. (2014) · Cell Reports

Alzheimer's disease research and treatmentsCellular transport and secretion

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β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function

Gao, Y., Hong, Y., Huang, L., Zheng, S., Zhang, H., Wang, S., Yao, Y., Zhao, Y., Zhu, L., Xu, Q., et al. (2023) · Cell

Neuroscience and Neuropharmacology ResearchDown syndrome and intellectual disability research

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ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity

Zhu, B., Jiang, L., Huang, T., Zhao, Y., Liu, T., Zhong, Y., Li, X., Campos, A., Pomeroy, K., Masliah, E., et al. (2017) · Nature Communications

Alzheimer's disease research and treatmentsEndoplasmic Reticulum Stress and Disease

Cited by 71

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein

Huang, T. Y., Zhao, Y., Li, X., Wang, X., Tseng, I.-C., Thompson, R., Tu, S., Willnow, T. E., Zhang, Y.-W., & Xu, H. (2016) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsCellular transport and secretion

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Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration

Zhang, H., Zhang, Y.-W., Chen, Y., Huang, X., Zhou, F., Wang, W., Xian, B., Zhang, X., Masliah, E., Chen, Q., et al. (2012) · The Journal of Neuroscience

Cell death mechanisms and regulationAlzheimer's disease research and treatments

Cited by 68

APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients

Zhang, H., Shao, L., Lin, Z., Long, Q.-X., Yuan, H., Cai, L., Jiang, G., Guo, X., Yang, R., Zhang, Z., et al. (2022) · Signal Transduction and Targeted Therapy

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 67

Effects of endogenous β‐amyloid overproduction on tau phosphorylation in cell culture

Wang, Z., Li, H., Li, X., Zhang, Q., Tian, Q., Wang, Q., Xu, H., & Wang, J. (2006) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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SORLA attenuates EphA4 signaling and amyloid β–induced neurodegeneration

Huang, T. Y., Zhao, Y., Jiang, L.-L., Li, X., Liu, Y., Sun, Y., Piña-Crespo, J. C., Zhu, B., Masliah, E., Willnow, T. E., et al. (2017) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

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The role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation

Hou, P., Liu, G., Zhao, Y., Shi, Z., Zheng, Q., Bu, G., Xu, H., & Zhang, Y.-W. (2015) · Neurobiology of Aging

Alzheimer's disease research and treatmentsTrace Elements in Health

Cited by 32

Correction: Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

Liu, C.-C., Kanekiyo, T., Xu, H., & Bu, G. (2013) · Nature Reviews Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 32

Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity

Wang, N., Cai, L., Pei, X., Lin, Z., Huang, L., Liang, C., Wei, M., Shao, L., Guo, T., Huang, F., et al. (2024) · iScience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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