Hunter, Tony

The protein kinase complement of the human genome

Manning, G., Whyte, D. B., Martinez, R., Hunter, T., & Sudarsanam, S. (2002) · Science

Protein Kinase Regulation and GTPase SignalingGenomics and Phylogenetic Studies

Cited by 8,145

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., et al. (2020) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 3,863

Oncogenic kinase signalling.

Blume-Jensen, P., & Hunter, T. (2001) · Nature

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 3,738

Signaling—2000 and Beyond

Hunter, T. (2000) · Cell

Protein Kinase Regulation and GTPase SignalingReceptor Mechanisms and Signaling

Cited by 2,586

Protein Tyrosine Phosphatases in the Human Genome

Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J., & Mustelin, T. (2004) · Cell

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 1,886

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

Schlaepfer, D. D., Hanks, S. K., Hunter, T., & Geer, P. V. D. (1994) · Nature

Cell Adhesion Molecules ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 1,595

Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

Sherman, M. H., Yu, R. T., Engle, D. D., Ding, N., Atkins, A. R., Tiriac, H., Collisson, E. A., Connor, F., Van Dyke, T., Kozlov, S., et al. (2014) · Cell

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 1,158

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

Angel, P., Allegretto, E. A., Okino, S. T., Hattori, K., Boyle, W. J., Hunter, T., & Karin, M. (1988) · Nature

Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 907

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Yang, W., Xia, Y., Hawke, D., Li, X., Liang, J., Xing, D., Aldape, K., Hunter, T., Alfred Yung, W. K., & Lu, Z. (2012) · Cell

Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics

Cited by 846

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Soppet, D., Escandon, E., Maragos, J., Middlemas, D. S., Raid, S. W., Blair, J., Burton, L. E., Stanton, B. R., Kaplan, D. R., Hunter, T., et al. (1991) · Cell

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

Cited by 820

Structure-based prediction of protein–protein interactions on a genome-wide scale

Zhang, Q. C., Petrey, D., Deng, L., Qiang, L., Shi, Y., Thu, C. A., Bisikirska, B., Lefebvre, C., Accili, D., Hunter, T., et al. (2012) · Nature

Bioinformatics and Genomic NetworksProtein Structure and Dynamics

Cited by 723

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

Zheng, X., Boyer, L., Jin, M., Mertens, J., Kim, Y., Ma, L., Ma, L., Hamm, M., Gage, F. H., & Hunter, T. (2016) · eLife

Neurogenesis and neuroplasticity mechanismsCancer, Hypoxia, and Metabolism

Cited by 671

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF β-TrCP

Watanabe, N., Arai, H., Nishihara, Y., Taniguchi, M., Watanabe, N., Hunter, T., & Osada, H. (2004) · Proceedings of the National Academy of Sciences

Ubiquitin and proteasome pathwaysMicrotubule and mitosis dynamics

Cited by 472

Roles of Chk1 in cell biology and cancer therapy

Zhang, Y., & Hunter, T. (2014) · International Journal of Cancer

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 462

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Shi, Y., Gao, W., Lytle, N. K., Huang, P., Yuan, X., Dann, A. M., Ridinger-Saison, M., DelGiorno, K. E., Antal, C. E., Liang, G., et al. (2019) · Nature

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 431

A growing coactivator network

Janknecht, R., & Hunter, T. (1996) · Nature

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 393

CtIP Links DNA Double-Strand Break Sensing to Resection

You, Z., Shi, L. Z., Zhu, Q., Wu, P., Zhang, Y.-W., Basilio, A., Tonnu, N., Verma, I. M., Berns, M. W., & Hunter, T. (2009) · Molecular Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 231

Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile

Kim, Y., Zheng, X., Ansari, Z., Bunnell, M. C., Herdy, J. R., Traxler, L., Lee, H., Paquola, A. C. M., Blithikioti, C., Ku, M., et al. (2018) · Cell Reports

Mitochondrial Function and PathologyPluripotent Stem Cells Research

Cited by 117

Site-specific incorporation of phosphotyrosine using an expanded genetic code

Hoppmann, C., Wong, A., Yang, B., Li, S., Hunter, T., Shokat, K. M., & Wang, L. (2017) · Nature Chemical Biology

Chemical Synthesis and AnalysisRNA and protein synthesis mechanisms

Cited by 112

The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity

Zheng, C., Xiang, J., Hunter, T., & Lin, A. (1999) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 110