The protein kinase complement of the human genome

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The sequence of the human genome

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Oncogenic kinase signalling.

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Signaling—2000 and Beyond

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Comparative Genomics of the Eukaryotes

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WNK1, a Novel Mammalian Serine/Threonine Protein Kinase Lacking the Catalytic Lysine in Subdomain II

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Extensive genomic duplication during early chordate evolution

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The protein kinases of budding yeast: six score and more

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The Protein Kinase Domain of the ANP Receptor Is Required for Signaling

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A phosphoserine‐regulated docking site in the protein kinase RSK2 that recruits and activates PDK1

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Crystal Structure of the Atypical Protein Kinase Domain of a TRP Channel with Phosphotransferase Activity

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Evidence of en bloc duplication in vertebrate genomes

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Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution

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KSR: a MAPK scaffold of the Ras pathway?

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The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination

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Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II.

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The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein

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Complex Effects of Naturally Occurring Mutations in the JAK3 Pseudokinase Domain: Evidence for Interactions between the Kinase and Pseudokinase Domains

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CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein

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Identification and Characterization of a Haploid Germ Cell-specific Nuclear ProteinKinase (Haspin) in Spermatid Nuclei and Its Effects on Somatic Cells

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Cloning and Characterization of a p53-related Protein Kinase Expressed in Interleukin-2-activated Cytotoxic T-cells, Epithelial Tumor Cell Lines, and the Testes

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AATYK: A novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells

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Bioinformatics and discovery: induction beckons again

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Genome duplication strikes back

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Maternally localized RNA encoding a serine/threonine protein kinase in the ascidian, Halocynthia roretzi

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Conserved linkage between the puffer fish (Fugu rubripes) and human genes for platelet-derived growth factor receptor and macrophage colony-stimulating factor receptor.Preprint

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Phosphorylation of Human MAD1 by the BUB1 Kinasein Vitro

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Sperm-Egg Binding Protein or Proto-Oncogene?

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Structural Basis for Nucleotide-dependent Regulation of Membrane-associated Guanylate Kinase-like Domains

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Integrin Adhesion: When Is a Kinase a Kinase?

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A New Gene–Pseudogene Fusion Allele Due to a Recombination in Intron 2 of the Glucocerebrosidase Gene Causes Gaucher Disease

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

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Comprehensive analysis of kinase inhibitor selectivity

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A quantitative analysis of kinase inhibitor selectivity

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

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Protein Tyrosine Phosphatases in the Human Genome

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ERK/MAPK signalling pathway and tumorigenesis (Review)

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Mechanisms of specificity in protein phosphorylation

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FAK in cancer: mechanistic findings and clinical applications

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The importance of intrinsic disorder for protein phosphorylation

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1

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Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

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Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

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The Genome of the Sea Urchin <i>Strongylocentrotus purpuratus</i>

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Mechanisms of receptor tyrosine kinase activation in cancer

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Kinase inhibitors: the road ahead

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Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

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Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes

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Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

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Specificity, versatility, and control of TGF-β family signaling

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Redox regulation of FoxO transcription factors

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Large-scale phosphorylation analysis of mouse liver

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An atlas of substrate specificities for the human serine/threonine kinome

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Signaling Receptors for TGF-β Family Members

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Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1

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Targeting the cancer kinome through polypharmacology

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Tau protein kinases: Involvement in Alzheimer's disease

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Biology of the TAM Receptors

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The casein kinase 1 family: participation in multiple cellular processes in eukaryotes

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Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

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Properties of FDA-approved small molecule protein kinase inhibitors

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Initiating Cellular Stress Responses

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Small-molecule kinase inhibitors: an analysis of FDA-approved drugs

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System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

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MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling

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Kinase mutations in human disease: interpreting genotype–phenotype relationships

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MAPKAP kinases — MKs — two's company, three's a crowd

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A combinatorial strategy for treating KRAS-mutant lung cancer

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Defining a new nomenclature for the structures of active and inactive kinases

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Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

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Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

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Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

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Irreversible Protein Kinase Inhibitors: Balancing the Benefits and Risks

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Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms

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The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

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Atypical mitogen-activated protein kinases: Structure, regulation and functions

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FOXP3+ regulatory T cells and their functional regulation

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Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

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Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple ‘Omic’ Layers

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Abiotic production of sugar phosphates and uridine ribonucleoside in aqueous microdroplets

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PROTACs: great opportunities for academia and industry (an update from 2020 to 2021)

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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

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On the Integration of In Silico Drug Design Methods for Drug Repurposing

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Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases

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Docking interactions in protein kinase and phosphatase networks

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CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases

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Recent Advances in Selective and Irreversible Covalent Ligand Development and Validation

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Mitochondrial dysfunction in Parkinson's disease

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Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.

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Role for KAP1 Serine 824 Phosphorylation and Sumoylation/Desumoylation Switch in Regulating KAP1-mediated Transcriptional Repression

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Substrate and Docking Interactions in Serine/Threonine Protein Kinases

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Current status of SRC inhibitors in solid tumor malignancies

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