Récher, Christian

International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts

Dombret, H., Seymour, J. F., Butrym, A., Wierzbowska, A., Selleslag, D., Jang, J. H., Kumar, R., Cavenagh, J., Schuh, A. C., Candoni, A., et al. (2015) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Farge, T., Saland, E., de Toni, F., Aroua, N., Hosseini, M., Perry, R., Bosc, C., Sugita, M., Stuani, L., Fraisse, M., et al. (2017) · Cancer Discovery

Acute Myeloid Leukemia ResearchCancer, Hypoxia, and Metabolism

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High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

Poulain, L., Sujobert, P., Zylbersztejn, F., Barreau, S., Stuani, L., Lambert, M., Palama, T. L., Chesnais, V, Birsen, R., Vergez, F., et al. (2017) · Leukemia

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

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Dendrogenin A drives LXR to trigger lethal autophagy in cancers

Segala, G., David, M., de Medina, P., Poirot, M. C., Serhan, N., Vergez, F., Mougel, A., Saland, E., Carayon, K., Leignadier, J., et al. (2017) · Nature Communications

Autophagy in Disease and TherapyCancer, Lipids, and Metabolism

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CHK1 as a therapeutic target to bypass chemoresistance in AML

David, L., Fernandez-Vidal, A., Bertoli, S., Grgurevic, S., Lepage, B., Deshaies, D., Prade, N., Cartel, M., Larrue, C., Sarry, J.-E., et al. (2016) · Science Signaling

Acute Myeloid Leukemia ResearchDNA Repair Mechanisms

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Magrolimab plus azacitidine vs physician’s choice for untreated TP53 -mutated acute myeloid leukemia: the ENHANCE-2 study

Zeidner, J. F., Sallman, D. A., Récher, C., Daver, N. G., Leung, A. Y. H., Hiwase, D. K., Subklewe, M., Pabst, T., Montesinos, P., Larson, R. A., et al. (2025) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

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