Talalay, Paul

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Chou, T.-C., & Talalay, P. (1984) · Advances in Enzyme Regulation

Computational Drug Discovery Methodsthermodynamics and calorimetric analyses

Cited by 7,178

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Dinkova-Kostova, A. T., Holtzclaw, W. D., Cole, R. N., Itoh, K., Wakabayashi, N., Katoh, Y., Yamamoto, M., & Talalay, P. (2002) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 1,947

A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure

Zhang, Y., Talalay, P., Cho, C. G., & Posner, G. H. (1992) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 1,682

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

Ramos-Gomez, M., Kwak, M.-K., Dolan, P. M., Itoh, K., Yamamoto, M., Talalay, P., & Kensler, T. W. (2001) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 1,102

Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

Wakabayashi, N., Dinkova-Kostova, A. T., Holtzclaw, W. D., Kang, M.-I., Kobayashi, A., Yamamoto, M., Kensler, T. W., & Talalay, P. (2004) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 986

Sulforaphane treatment of autism spectrum disorder (ASD)

Singh, K., Connors, S. L., Macklin, E. A., Smith, K. D., Fahey, J. W., Talalay, P., & Zimmerman, A. W. (2014) · Proceedings of the National Academy of Sciences

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 449

Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone.

Gordon, G. B., Shantz, L. M., & Talalay, P. (1987) · Advances in Enzyme Regulation

Estrogen and related hormone effectsMetabolism, Diabetes, and Cancer

Cited by 159

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China

Kensler, T. W., Ng, D., Carmella, S. G., Chen, M., Jacobson, L. P., Muñoz, A., Egner, P. A., Chen, J. G., Qian, G. S., Chen, T. Y., et al. (2012) · Carcinogenesis

Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 128

Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial

Wise, R. A., Holbrook, J. T., Criner, G., Sethi, S., Rayapudi, S., Sudini, K. R., Sugar, E. A., Burke, A., Thimmulappa, R., Singh, A., et al. (2016) · PLOS ONE

Genomics, phytochemicals, and oxidative stressChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 124