Mullins, Robert F.

A role for local inflammation in the formation of drusen in the aging eye

Anderson, D. H., Mullins, R. F., Hageman, G. S., & Johnson, L. V. (2002) · American Journal of Ophthalmology

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 1,087

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

Mullins, R. F., Russell, S. R., Anderson, D. H., & Hageman, G. S. (2000) · The FASEB Journal

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 937

Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation

Anderson, D. H., Ozaki, S., Nealon, M., Neitz, J., Mullins, R. F., Hageman, G. S., & Johnson, L. V. (2001) · American Journal of Ophthalmology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 255

Structure and composition of drusen associated with glomerulonephritis: Implications for the role of complement activation in drusen biogenesis

Mullins, R. F., Aptsiauri, N., & Hageman, G. S. (2001) · Eye

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 231

Decreased Thickness and Integrity of the Macular Elastic Layer of Bruch's Membrane Correspond to the Distribution of Lesions Associated with Age-Related Macular Degeneration

Chong, N. H. V., Keonin, J., Luthert, P. J., Frennesson, C. I., Weingeist, D. M., Wolf, R. L., Mullins, R. F., & Hageman, G. S. (2005) · The American Journal of Pathology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 218

Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells

Hageman, G. S., Mullins, R. F., Russell, S. R., Johnson, L. V., & Anderson, D. H. (1999) · The FASEB Journal

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 206

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case–control study

Ennis, S., Jomary, C., Mullins, R., Cree, A., Chen, X., MacLeod, A., Jones, S., Collins, A., Stone, E., & Lotery, A. (2008) · The Lancet

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 171

Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells

Skeie, J. M., Fingert, J. H., Russell, S. R., Stone, E. M., & Mullins, R. F. (2010) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 114

Adeno-Associated Virus Type 5: Transduction Efficiency and Cell-Type Specificity in the Primate Retina

Lotery, A. J., Yang, G. S., Mullins, R. F., Russell, S. R., Schmidt, M., Stone, E. M., Lindbloom, J. D., Chiorini, J. A., Kotin, R. M., & Davidson, B. L. (2003) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 107

Association of HLA Class I and Class II Polymorphisms with Age-Related Macular Degeneration

Goverdhan, S. V., Howell, M. W., Mullins, R. F., Osmond, C., Hodgkins, P. R., Self, J., Avery, K., & Lotery, A. J. (2005) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 78

Retinal tropism and transduction of adeno-associated virus varies by serotype and route of delivery (intravitreal, subretinal, or suprachoroidal) in rats

Han, I. C., Cheng, J. L., Burnight, E. R., Ralston, C. L., Fick, J. L., Thomsen, G. J., Tovar, E. F., Russell, S. R., Sohn, E. H., Mullins, R. F., et al. (2020) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 60

Molecular response of chorioretinal endothelial cells to complement injury: Implications for macular degeneration

Zeng, S., Whitmore, S. S., Sohn, E. H., Riker, M. J., Wiley, L. A., Scheetz, T. E., Stone, E. M., Tucker, B. A., & Mullins, R. F. (2016) · The Journal of Pathology

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 56

Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies

Lee, W.-H., Higuchi, H., Ikeda, S., Macke, E. L., Takimoto, T., Pattnaik, B. R., Liu, C., Chu, L.-F., Siepka, S. M., Krentz, K. J., et al. (2016) · eLife

Mitochondrial Function and PathologyRetinal Development and Disorders

Cited by 52

Fcγ Receptor Upregulation Is Associated With Immune Complex Inflammation in the Mouse Retina and Early Age-Related Macular Degeneration

Murinello, S., Mullins, R. F., Lotery, A. J., Perry, V. H., & Teeling, J. L. (2014) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 51

The degree of adeno-associated virus-induced retinal inflammation varies based on serotype and route of delivery: intravitreal, subretinal, or suprachoroidal

Wiley, L. A., Boyce, T. M., Meyering, E. E., Ochoa, D., Sheehan, K. M., Stone, E. M., Mullins, R. F., Tucker, B. A., & Han, I. C. (2023) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 30

Helper-dependent adenovirus transduces the human and rat retina but elicits an inflammatory reaction when delivered subretinally in rats

Han, I. C., Burnight, E. R., Ulferts, M. J., Worthington, K. S., Russell, S. R., Sohn, E. H., Mullins, R. F., Stone, E. M., Tucker, B. A., & Wiley, L. A. (2019) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 30