Kapoor, Tarun M.

Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5

Kapoor, T. M., Mayer, T. U., Coughlin, M. L., & Mitchison, T. J. (2000) · The Journal of Cell Biology

Microtubule and mitosis dynamicsHeterocyclic Compound Synthesis and Bioactivity

Cited by 717

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

Kapitein, L. C., Peterman, E. J. G., Kwok, B. H., Kim, J. H., Kapoor, T. M., & Schmidt, C. F. (2005) · Nature

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 678

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

Firestone, A. J., Weinger, J. S., Maldonado, M., Barlan, K., Langston, L. D., O’Donnell, M., Gelfand, V. I., Kapoor, T. M., & Chen, J. K. (2012) · Nature

Genetic and Kidney Cyst DiseasesMicrotubule and mitosis dynamics

Cited by 403

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

He, M., Subramanian, R., Bangs, F., Omelchenko, T., Liem Jr, K. F., Kapoor, T. M., & Anderson, K. V. (2014) · Nature Cell Biology

Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies

Cited by 302

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

Foley, E. A., Maldonado, M., & Kapoor, T. M. (2011) · Nature Cell Biology

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 267

Microtubule cross-linking triggers the directional motility of kinesin-5

Kapitein, L. C., Kwok, B. H., Weinger, J. S., Schmidt, C. F., Kapoor, T. M., & Peterman, E. J. G. (2008) · The Journal of Cell Biology

Microtubule and mitosis dynamicsAdvanced Fluorescence Microscopy Techniques

Cited by 143

Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex

Wieczorek, M., Urnavicius, L., Ti, S.-C., Molloy, K. R., Chait, B. T., & Kapoor, T. M. (2020) · Cell

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 136

Asymmetric molecular architecture of the human γ -tubulin ring complex

Wieczorek, M., Urnavicius, L., Ti, S.-C., Molloy, K. R., Chait, B. T., & Kapoor, T. M. (2019) · Cell

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 136

Allosteric inhibition of kinesin-5 modulates its processive directional motility

Kwok, B. H., Kapitein, L. C., Kim, J. H., Peterman, E. J. G., Schmidt, C. F., & Kapoor, T. M. (2006) · Nature Chemical Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 108

A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding

Weinger, J. S., Qiu, M., Yang, G., & Kapoor, T. M. (2011) · Current Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 100

A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells

Kleiner, R. E., Hang, L. E., Molloy, K. R., Chait, B. T., & Kapoor, T. M. (2018) · Cell Chemical Biology

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 73