Alvarez, Jorge Ivan

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

Rothhammer, V., Mascanfroni, I. D., Bunse, L., Takenaka, M. C., Kenison, J. E., Mayo, L., Chao, C.-C., Patel, B., Yan, R., Blain, M., et al. (2016) · Nature Medicine

Tryptophan and brain disordersinterferon and immune responses

Cited by 1,559

Microglial control of astrocytes in response to microbial metabolites

Rothhammer, V., Borucki, D. M., Tjon, E. C., Takenaka, M. C., Chao, C.-C., Ardura-Fabregat, A., de Lima, K. A., Gutiérrez-Vázquez, C., Hewson, P., Staszewski, O., et al. (2018) · Nature

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 1,051

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

Alvarez, J. I., Dodelet-Devillers, A., Kebir, H., Ifergan, I., Fabre, P. J., Terouz, S., Sabbagh, M., Wosik, K., Bourbonnière, L., Bernard, M., et al. (2011) · Science

Barrier Structure and Function StudiesHedgehog Signaling Pathway Studies

Cited by 845

Preferential recruitment of interferon‐γ–expressing T H 17 cells in multiple sclerosis

Kebir, H., Ifergan, I., Alvarez, J. I., Bernard, M., Poirier, J., Arbour, N., Duquette, P., & Prat, A. (2009) · Annals of Neurology

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 551

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

Larochelle, C., Alvarez, J. I., & Prat, A. (2011) · FEBS Letters

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 405

Disruption of central nervous system barriers in multiple sclerosis

Alvarez, J. I., Cayrol, R., & Prat, A. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 334

Review: Leucocyte–endothelial cell crosstalk at the blood–brain barrier: A prerequisite for successful immune cell entry to the brain

Greenwood, J., Heasman, S. J., Alvarez, J. I., Prat, A., Lyck, R., & Engelhardt, B. (2011) · Neuropathology and Applied Neurobiology

Barrier Structure and Function StudiesCell Adhesion Molecules Research

Cited by 240

Netrin 1 regulates blood–brain barrier function and neuroinflammation

Podjaski, C., Alvarez, J. I., Bourbonniere, L., Larouche, S., Terouz, S., Bin, J. M., Lécuyer, M.-A., Saint-Laurent, O., Larochelle, C., Darlington, P. J., et al. (2015) · Brain

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 185

Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions

Alvarez, J. I., Saint-Laurent, O., Godschalk, A., Terouz, S., Briels, C., Larouche, S., Bourbonnière, L., Larochelle, C., & Prat, A. (2015) · Neurobiology of Disease

Multiple Sclerosis Research StudiesBarrier Structure and Function Studies

Cited by 150

Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system

Larochelle, C., Cayrol, R., Kebir, H., Alvarez, J. I., Lécuyer, M.-A., Ifergan, I., Viel, É., Bourbonnière, L., Beauseigle, D., Terouz, S., et al. (2012) · Brain

Multiple Sclerosis Research StudiesCell Adhesion Molecules Research

Cited by 145