The first multicenter, randomized, controlled trial of home telemonitoring for Japanese patients with heart failure: home telemonitoring study for patients with heart failure (HOMES-HF)
Abstract
Home telemonitoring is becoming more important to home medical care for patients with heart failure. Since there are no data on home telemonitoring for Japanese patients with heart failure, we investigated its effect on cardiovascular outcomes. The HOMES-HF study was the first multicenter, open-label, randomized, controlled trial (RCT) to elucidate the effectiveness of home telemonitoring of physiological data, such as body weight, blood pressure, and pulse rate, for Japanese patients with heart failure (UMIN Clinical Trials Registry 000006839). The primary end-point was a composite of all-cause death or rehospitalization due to worsening heart failure. We analyzed 181 recently hospitalized patients with heart failure who were randomly assigned to a telemonitoring group (n = 90) or a usual care group (n = 91). The mean follow-up period was 15 (range 0-31) months. There was no statistically significant difference in the primary end-point between groups [hazard ratio (HR), 0.95; 95% confidence interval (CI), 0.548-1.648; p = 0.572]. Home telemonitoring for Japanese patients with heart failure was feasible; however, beneficial effects in addition to those of usual care were not demonstrated. Further investigation of more patients with severe heart failure, participation of home medical care providers, and use of a more integrated home telemonitoring system emphasizing communication as well as monitoring of symptoms and physiological data are required.
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4 (33%) of the 12 studies showed no difference in adherence when compared with a comparator.
“whereas 4 (33%) [30,51,66,84] showed no difference when compared with a comparator.”
From Interactive Remote Patient Monitoring Devices for Managing Chronic Health Conditions: Systematic Review and Meta-analysis (2022) · cites this paper as [66]
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- Authors
- On behalf of the HOMES-HF study investigators, Kotooka, N., Kitakaze, M., Nagashima, K., Asaka, M., Kinugasa, Y., Nochioka, K., Mizuno, A., Nagatomo, D., Mine, D., Yamada, Y., Kuratomi, A., Okada, N., Fujimatsu, D., Kuwahata, S., Toyoda, S., Hirotani, S.-I., Komori, T., Eguchi, K., Kario, K., Inomata, T., Sugi, K., Yamamoto, K., Tsutsui, H., Masuyama, T., Shimokawa, H., Momomura, S.-I., Seino, Y., Sato, Y., Inoue, T., & Node, K.
- Affiliations
- Saga University (JP)
- Chiba University (JP)
- Tohoku University (JP)
- Jichi Medical University (JP)
- Oita University (JP)
- Dokkyo Medical University (JP)
- Hyogo Medical University (JP)
- Toho University Ohashi Medical Center (JP)
- Hokkaido University (JP)
- Corresponding author
- Kotooka, Norihiko
- ORCID
- Kotooka, Norihiko
- Kitakaze, Masafumi
- Nagashima, Kengo
- Kinugasa, Yoshiharu
- Nochioka, Kotaro
- Mizuno, Atsushi
- Nagatomo, Daisuke
- Yamada, Yoko
- Okada, Norihiro
- Kuwahata, So
- Toyoda, Shigeru
- Komori, Takahiro
- Kario, Kazuomi
- Inomata, Takayuki
- Yamamoto, Kazuhiro
- Tsutsui, Hiroyuki
- Shimokawa, Hiroaki
- Momomura, Shin-ichi
- Seino, Yoshihiko
- Sato, Yasunori
- Inoue, Teruo
- Node, Koichi
- Venue
- Heart and Vessels
- Published
- 2018-02-15
- Volume
- 33
- Issue
- 8
- Pages
- 866-876
- ISSN
- 0910-8327 (ISSN-L)
- 1615-2573
- OpenAlex
- W2789058784
- Cited by
- 66
- References
- 35
- Citations by year
- 2026: 4 · 2025: 11 · 2024: 7 · 2023: 8 · 2022: 11 · 2021: 17 · 2020: 5 · 2019: 2 · 2018: 1
- FWCI
- 4.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Heart and Vessels (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion)
- Funders
- Japanese Ministry of Health, Labor, and Welfare (Comprehensive Research on Aging, Health (KR23000003), Health (KR24000001))
- Japan Society for the Promotion of Science KAKENHI (JP17K09510)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- home health monitoring, heart failure, Japanese patients, cardiovascular outcomes, all-cause mortality, heart failure readmission, home medical care, physiological monitoring
- MeSH terms
- Aged, Female, Follow-Up Studies, Heart Failure, Hemodynamics, Home Care Services, Humans, Japan, Male, Monitoring, Physiologic, Morbidity, Prospective Studies, Telemedicine, Disease Management
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