Pajvani, Utpal B.

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

Pajvani, U. B., Hawkins, M., Combs, T. P., Rajala, M. W., Doebber, T., Berger, J. P., Wagner, J. A., Wu, M., Knopps, A., Xiang, A. H., et al. (2004) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,163

Adiponectin acts in the brain to decrease body weight

Qi, Y., Takahashi, N., Hileman, S. M., Patel, H. R., Berg, A. H., Pajvani, U. B., Scherer, P. E., & Ahima, R. S. (2004) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 809

Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis

Schwabe, R. F., Tabas, I., & Pajvani, U. B. (2020) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 671

A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

Combs, T. P., Pajvani, U. B., Berg, A. H., Lin, Y., Jelicks, L. A., Laplante, M., Nawrocki, A. R., Rajala, M. W., Parlow, A. F., Cheeseboro, L., et al. (2004) · Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 545

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

Filliol, A., Saito, Y., Nair, A., Dapito, D. H., Yu, L.-X., Ravichandra, A., Bhattacharjee, S., Affo, S., Fujiwara, N., Su, H., et al. (2022) · Nature

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 349

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

Pajvani, U. B., Trujillo, M. E., Combs, T. P., Iyengar, P., Jelicks, L., Roth, K. A., Kitsis, R. N., & Scherer, P. E. (2005) · Nature Medicine

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 322

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis

Zhu, C., Kim, K., Wang, X., Bartolome, A., Salomao, M., Dongiovanni, P., Meroni, M., Graham, M. J., Yates, K. P., Diehl, A. M., et al. (2018) · Science Translational Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 250

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

Wang, X., Cai, B., Yang, X., Sonubi, O. O., Zheng, Z., Ramakrishnan, R., Shi, H., Valenti, L., Pajvani, U. B., Sandhu, J., et al. (2020) · Cell Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 204

Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?

Valenti, L., Bugianesi, E., Pajvani, U., & Targher, G. (2016) · Liver International

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 171

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling

Bartolomé, A., García-Aguilar, A., Asahara, S.-I., Kido, Y., Guillén, C., Pajvani, U. B., & Benito, M. (2017) · Molecular and Cellular Biology

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 141

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis

Yu, J., Zhu, C., Wang, X., Kim, K., Bartolome, A., Dongiovanni, P., Yates, K. P., Valenti, L., Carrer, M., Sadowski, T., et al. (2021) · Science Translational Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 132

Maladaptive regeneration - the reawakening of developmental pathways in NASH and fibrosis

Zhu, C., Tabas, I., Schwabe, R. F., & Pajvani, U. B. (2021) · Nature Reviews Gastroenterology & Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 112

Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

Joseph, L. C., Barca, E., Subramanyam, P., Komrowski, M., Pajvani, U., Colecraft, H. M., Hirano, M., & Morrow, J. P. (2016) · PLOS ONE

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 99

Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis

Richter, L. R., Wan, Q., Wen, D., Zhang, Y., Yu, J., Kang, J. K., Zhu, C., McKinnon, E. L., Gu, Z., Qiang, L., et al. (2020) · ACS Nano

Liver Disease Diagnosis and TreatmentNanoparticle-Based Drug Delivery

Cited by 59

Zonation in NASH – A key paradigm for understanding pathophysiology and clinical outcomes

Steinman, J. B., Salomao, M. A., & Pajvani, U. B. (2021) · Liver International

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 49

γ-secretase inhibition lowers plasma triglyceride-rich lipoproteins by stabilizing the LDL receptor

Kim, K., Goldberg, I. J., Graham, M. J., Sundaram, M., Bertaggia, E., Lee, S. X., Qiang, L., Haeusler, R. A., Metzger, D., Chambon, P., et al. (2018) · Cell Metabolism

Cholesterol and Lipid MetabolismLipid metabolism and disorders

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