Outeiro, Tiago F.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Hansen, C., Angot, E., Bergström, A.-L., Steiner, J. A., Pieri, L., Paul, G., Outeiro, T. F., Melki, R., Kallunki, P., Fog, K., et al. (2011) · Journal of Clinical Investigation

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

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Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein

Willingham, S., Outeiro, T. F., DeVit, M. J., Lindquist, S. L., & Muchowski, P. J. (2003) · Science

Genetic Neurodegenerative DiseasesParkinson's Disease Mechanisms and Treatments

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Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

Mollenhauer, B., Cullen, V., Kahn, I., Krastins, B., Outeiro, T. F., Pepivani, I., Ng, J., Schulz-Schaeffer, W., Kretzschmar, H. A., McLean, P. J., et al. (2008) · Experimental Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

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Dementia with Lewy bodies: an update and outlook

Outeiro, T. F., Koss, D. J., Erskine, D., Walker, L., Kurzawa-Akanbi, M., Burn, D., Donaghy, P., Morris, C., Taylor, J.-P., Thomas, A., et al. (2019) · Molecular Neurodegeneration

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

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Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy

Richter, K. N., Revelo, N. H., Seitz, K. J., Helm, M. S., Sarkar, D., Saleeb, R. S., D'Este, E., Eberle, J., Wagner, E., Vogl, C., et al. (2018) · The EMBO Journal

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

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Protein phosphorylation in neurodegeneration: friend or foe?

Tenreiro, S., Eckermann, K., & Outeiro, T. F. (2014) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

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Tau deletion promotes brain insulin resistance

Marciniak, E., Leboucher, A., Caron, E., Ahmed, T., Tailleux, A., Dumont, J., Issad, T., Gerhardt, E., Pagesy, P., Vileno, M., et al. (2017) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

Ghanem, S. S., Majbour, N. K., Vaikath, N. N., Ardah, M. T., Erskine, D., Jensen, N. M., Fayyad, M., Sudhakaran, I. P., Vasili, E., Melachroinou, K., et al. (2022) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

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Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

Paiva, I., Pinho, R., Pavlou, M. A., Hennion, M., Wales, P., Schütz, A.-L., Rajput, A., Szegő, É. M., Kerimoglu, C., Gerhardt, E., et al. (2017) · Human Molecular Genetics

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease

Tatenhorst, L., Eckermann, K., Dambeck, V., Fonseca-Ornelas, L., Walle, H., Lopes da Fonseca, T., Koch, J. C., Becker, S., Tönges, L., Bähr, M., et al. (2016) · Acta Neuropathologica Communications

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies

Schildknecht, S., Gerding, H. R., Karreman, C., Drescher, M., Lashuel, H. A., Outeiro, T. F., Di Monte, D. A., & Leist, M. (2013) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies

Brás, I. C., & Outeiro, T. F. (2021) · Cells

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

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Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease

Moreira, S., Fonseca, I., Nunes, M. J., Rosa, A., Lemos, L., Rodrigues, E., Carvalho, A. N., Outeiro, T. F., Rodrigues, C. M. P., Gama, M. J., et al. (2017) · Experimental Neurology

Parkinson's Disease Mechanisms and TreatmentsGenomics, phytochemicals, and oxidative stress

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One-step nanoscale expansion microscopy reveals individual protein shapes

Shaib, A. H., Chouaib, A. A., Chowdhury, R., Altendorf, J., Mihaylov, D., Zhang, C., Krah, D., Imani, V., Spencer, R. K. W., Georgiev, S. V., et al. (2025) · Nature Biotechnology

Advanced Fluorescence Microscopy TechniquesForce Microscopy Techniques and Applications

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Doxycycline Inhibits α-Synuclein-Associated Pathologies in Vitro and in Vivo

Dominguez-Meijide, A., Parrales, V., Vasili, E., González-Lizárraga, F., König, A., Lázaro, D. F., Lannuzel, A., Haik, S., Del Bel, E., Chehín, R., et al. (2021) · Neurobiology of Disease

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Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase

Miller-Fleming, L., Antas, P., Pais, T. F., Smalley, J. L., Giorgini, F., & Outeiro, T. F. (2014) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsFungal and yeast genetics research

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Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

Hatton, C., Ghanem, S. S., Koss, D. J., Abdi, I. Y., Gibbons, E., Guerreiro, R., Bras, J., International DLB Genetics Consortium, Bras, J., Guerreiro, R., et al. (2022) · Brain

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

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