Sadreyev, Ruslan I.

Macrophages Facilitate Electrical Conduction in the Heart

Hulsmans, M., Clauss, S., Xiao, L., Aguirre, A. D., King, K. R., Hanley, A., Hucker, W. J., Wülfers, E. M., Seemann, G., Courties, G., et al. (2017) · Cell

Cardiac electrophysiology and arrhythmiasConnexins and lens biology

Cited by 1,011

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Hata, A. N., Niederst, M. J., Archibald, H. L., Gomez-Caraballo, M., Siddiqui, F. M., Mulvey, H. E., Maruvka, Y. E., Ji, F., Bhang, H.-E. C., Krishnamurthy Radhakrishna, V., et al. (2016) · Nature Medicine

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 985

Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia

Sykes, D. B., Kfoury, Y. S., Mercier, F. E., Wawer, M. J., Law, J. M., Haynes, M. K., Lewis, T. A., Schajnovitz, A., Jain, E., Lee, D., et al. (2016) · Cell

Acute Myeloid Leukemia ResearchBiochemical and Molecular Research

Cited by 500

The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF

Savji, N., Meijers, W. C., Bartz, T. M., Bhambhani, V., Cushman, M., Nayor, M., Kizer, J. R., Sarma, A., Blaha, M. J., Gansevoort, R. T., et al. (2018) · JACC: Heart Failure

Cardiovascular Function and Risk FactorsHeart Failure Treatment and Management

Cited by 499

TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease

Griciuc, A., Patel, S., Federico, A. N., Choi, S. H., Innes, B. J., Oram, M. K., Cereghetti, G., McGinty, D., Anselmo, A., Sadreyev, R. I., et al. (2019) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 378

Polycomb repressive Complex 1 generates discrete compacted domains that change during differentiation

Kundu, S., Ji, F., Sunwoo, H., Jain, G., Lee, J. T., Sadreyev, R. I., Dekker, J., & Kingston, R. E. (2017) · Molecular Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 333

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease

McAlpine, C. S., Park, J., Griciuc, A., Kim, E., Choi, S. H., Iwamoto, Y., Kiss, M. G., Christie, K. A., Vinegoni, C., Poller, W. C., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 322

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Frodermann, V., Rohde, D., Courties, G., Severe, N., Schloss, M. J., Amatullah, H., McAlpine, C. S., Cremer, S., Hoyer, F. F., Ji, F., et al. (2019) · Nature Medicine

Hematopoietic Stem Cell TransplantationExercise and Physiological Responses

Cited by 292

Brain motor and fear circuits regulate leukocytes during acute stress

Poller, W. C., Downey, J., Mooslechner, A. A., Khan, N., Li, L., Chan, C. T., McAlpine, C. S., Xu, C., Kahles, F., He, S., et al. (2022) · Nature

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 234

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Patra, K. C., Kato, Y., Mizukami, Y., Widholz, S., Boukhali, M., Revenco, I., Grossman, E. A., Ji, F., Sadreyev, R. I., Liss, A. S., et al. (2018) · Nature Cell Biology

Pancreatic and Hepatic Oncology ResearchCancer, Lipids, and Metabolism

Cited by 192

Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease

Kwak, S. S., Washicosky, K. J., Brand, E., von Maydell, D., Aronson, J., Kim, S., Capen, D. E., Cetinbas, M., Sadreyev, R., Ning, S., et al. (2020) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 151

Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction

Nishikawa, J. L., Boeszoermenyi, A., Vale-Silva, L. A., Torelli, R., Posteraro, B., Sohn, Y.-J., Ji, F., Gelev, V., Sanglard, D., Sanguinetti, M., et al. (2016) · Nature

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 146

Monocytes re-enter the bone marrow during fasting and alter the host response to infection

Janssen, H., Kahles, F., Liu, D., Downey, J., Koekkoek, L. L., Roudko, V., D’Souza, D., McAlpine, C. S., Halle, L., Poller, W. C., et al. (2023) · Immunity

Dietary Effects on HealthImmune responses and vaccinations

Cited by 142

IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1

Dai, N., Ji, F., Wright, J., Minichiello, L., Sadreyev, R., & Avruch, J. (2017) · eLife

Growth Hormone and Insulin-like Growth FactorsRNA Research and Splicing

Cited by 103

Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction

Mueller, B., Mieczkowski, J., Kundu, S., Wang, P., Sadreyev, R., Tolstorukov, M. Y., & Kingston, R. E. (2017) · Genes & Development

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 100

A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction

Sato, T., Verma, S., Andrade, C. D. C., Omeara, M., Campbell, N., Wang, J. S., Cetinbas, M., Lang, A., Ausk, B. J., Brooks, D. J., et al. (2020) · Nature Communications

Bone Metabolism and DiseasesCellular Mechanics and Interactions

Cited by 86

Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification

Clarke, T. L., Tang, R., Chakraborty, D., Van Rechem, C., Ji, F., Mishra, S., Ma, A., Kaniskan, H. Ü., Jin, J., Lawrence, M. S., et al. (2020) · Cancer Discovery

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 50

Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesis

Martin, O. P., Wallace, M. S., Oetheimer, C., Patel, H. B., Butler, E. C., Wong, L. P., Huang, P., Elbaz, J., Costentin, C., Salloum, S., et al. (2025) · Nature Immunology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 45

WSTF nuclear autophagy regulates chronic but not acute inflammation

Wang, Y., Eapen, V. V., Liang, Y., Kournoutis, A., Sherman, M. S., Xu, Y., Onorati, A., Li, X., Zhou, X., Corey, K. E., et al. (2025) · Nature

Autophagy in Disease and TherapyGenomics and Chromatin Dynamics

Cited by 30

The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function

Pilat, D. J., Le, H., Prokopenko, D., Lin, C.-C. J., Eimer, W. A., Quinti, L., Gavrilles, E. P., Garcia, S. N., Heitman, S. N., McGinty, D., et al. (2026) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 14