Dillin, Andrew

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., et al. (2011) · Science

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 2,600

Adapting Proteostasis for Disease Intervention

Balch, W. E., Morimoto, R. I., Dillin, A., & Kelly, J. W. (2008) · Science

Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms

Cited by 2,495

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

Powers, E. T., Morimoto, R. I., Dillin, A., Kelly, J. W., & Balch, W. E. (2009) · Annual Review of Biochemistry

Heat shock proteins researchEndoplasmic Reticulum Stress and Disease

Cited by 1,149

Rates of Behavior and Aging Specified by Mitochondrial Function During Development

Dillin, A., Hsu, A.-L., Arantes-Oliveira, N., Lehrer-Graiwer, J., Hsin, H., Fraser, A. G., Kamath, R. S., Ahringer, J., & Kenyon, C. (2002) · Science

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 1,121

The Cell Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

Durieux, J., Wolff, S., & Dillin, A. (2011) · Cell

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 1,059

Opposing activities protect against age-onset proteotoxicity

Cohen, E., Bieschke, J., Perciavalle, R. M., Kelly, J. W., & Dillin, A. (2006) · Science

Genetics, Aging, and Longevity in Model OrganismsAlzheimer's disease research and treatments

Cited by 843

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy

Nguyen, T. B., Louie, S. M., Daniele, J. R., Tran, Q., Dillin, A., Zoncu, R., Nomura, D. K., & Olzmann, J. A. (2017) · Developmental Cell

Lipid metabolism and biosynthesisAutophagy in Disease and Therapy

Cited by 610

Aging as an event of proteostasis collapse

Taylor, R. C., & Dillin, A. (2011) · Cold Spring Harbor Perspectives in Biology

Genetics, Aging, and Longevity in Model OrganismsHeat shock proteins research

Cited by 538

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

Cohen, E., Paulsson, J. F., Blinder, P., Burstyn-Cohen, T., Du, D., Estepa, G., Adame, A., Pham, H. M., Holzenberger, M., Kelly, J. W., et al. (2009) · Cell

Alzheimer's disease research and treatmentsGenetics, Aging, and Longevity in Model Organisms

Cited by 488

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

Vilchez, D., Morantte, I., Liu, Z., Douglas, P. M., Merkwirth, C., Rodrigues, A. P. C., Manning, G., & Dillin, A. (2012) · Nature

Genetics, Aging, and Longevity in Model OrganismsUbiquitin and proteasome pathways

Cited by 413

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

Mair, W., Morantte, I., Rodrigues, A. P. C., Manning, G., Montminy, M., Shaw, R. J., & Dillin, A. (2011) · Nature

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 393

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

Vilchez, D., Boyer, L., Morantte, I., Lutz, M., Merkwirth, C., Joyce, D., Spencer, B., Page, L., Masliah, E., Berggren, W. T., et al. (2012) · Nature

Ubiquitin and proteasome pathwaysAutophagy in Disease and Therapy

Cited by 388

Mitochondrial stress induces chromatin reorganization to promote longevity and UPR(mt)

Tian, Y., Garcia, G., Bian, Q., Steffen, K. K., Joe, L., Wolff, S., Meyer, B. J., & Dillin, A. (2016) · Cell

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 370

Two conserved histone demethylases regulate mitochondrial stress-induced longevity

Merkwirth, C., Jovaisaite, V., Durieux, J., Matilainen, O., Jordan, S. D., Quiros, P. M., Steffen, K. K., Williams, E. G., Mouchiroud, L., Tronnes, S. U., et al. (2016) · Cell

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 363

Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., Jahan, N., Chin, G., Mihaly, E., Lin, J. M., et al. (2019) · Science Translational Medicine

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 257

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

Riedel, C. G., Dowen, R. H., Lourenco, G. F., Kirienko, N. V., Heimbucher, T., West, J. A., Bowman, S. K., Kingston, R. E., Dillin, A., Asara, J. M., et al. (2013) · Nature Cell Biology

FOXO transcription factor regulationGenetics, Aging, and Longevity in Model Organisms

Cited by 207

The Sense of Smell Impacts Metabolic Health and Obesity

Riera, C. E., Tsaousidou, E., Halloran, J., Follett, P., Hahn, O., Pereira, M. M. A., Ruud, L. E., Alber, J., Tharp, K., Anderson, C. M., et al. (2017) · Cell Metabolism

Regulation of Appetite and ObesityAdipose Tissue and Metabolism

Cited by 191

Signaling networks determining life span

Riera, C. E., Merkwirth, C., De Magalhaes Filho, C. D., & Dillin, A. (2016) · Annual Review of Biochemistry

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 161

Tipping the metabolic scales towards increased longevity in mammals

Riera, C. E., & Dillin, A. (2015) · Nature Cell Biology

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 153

Measuring expression heterogeneity of single-cell cytoskeletal protein complexes

Vlassakis, J., Hansen, L. L., Higuchi-Sanabria, R., Zhou, Y., Tsui, C. K., Dillin, A., Huang, H., & Herr, A. E. (2021) · Nature Communications

Cellular Mechanics and InteractionsAdvanced Proteomics Techniques and Applications

Cited by 16

Measuring expression heterogeneity of single-cell cytoskeletal protein complexes

Vlassakis, J., Hansen, L. L., Higuchi-Sanabria, R., Zhou, Y., Tsui, C. K., Dillin, A., Huang, H., & Herr, A. E. (2020) · Nature Communications

Cellular Mechanics and InteractionsAdvanced Proteomics Techniques and Applications

Cited by 16