Wong, Wing Hung

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection.

Li, C., & Wong, W. H. (2001) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 3,133

Genomic responses in mouse models poorly mimic human inflammatory diseases

Seok, J., Warren, H. S., Cuenca, A. G., Mindrinos, M. N., Baker, H. V., Xu, W., Richards, D. R., McDonald-Smith, G. P., Gao, H., Hennessy, L., et al. (2013) · Proceedings of the National Academy of Sciences

Animal testing and alternativesImmune Response and Inflammation

Cited by 3,005

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

Hakak, Y., Walker, J. R., Li, C., Wong, W. H., Davis, K. L., Buxbaum, J. D., Haroutunian, V., & Fienberg, A. A. (2001) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 1,192

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

Paik, J.-H., Kollipara, R., Chu, G., Ji, H., Xiao, Y., Ding, Z., Miao, L., Tothova, Z., Horner, J. W., Carrasco, D. R., et al. (2007) · Cell

FOXO transcription factor regulationHippo pathway signaling and YAP/TAZ

Cited by 1,032

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

Zheng, H., Ying, H., Yan, H., Kimmelman, A. C., Hiller, D. J., Chen, A.-J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z., et al. (2008) · Nature

Glioma Diagnosis and TreatmentCancer-related Molecular Pathways

Cited by 767

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

Paik, J.-H., Ding, Z., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S.-S., Zheng, H., Ying, H., Mahoney, J., et al. (2009) · Cell Stem Cell

FOXO transcription factor regulationNeurogenesis and neuroplasticity mechanisms

Cited by 459

Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis

Sahraeian, S. M. E., Mohiyuddin, M., Sebra, R., Tilgner, H., Afshar, P. T., Au, K. F., Bani Asadi, N., Gerstein, M. B., Wong, W. H., Snyder, M. P., et al. (2017) · Nature Communications

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 376

Characterization of the human ESC transcriptome by hybrid sequencing

Au, K. F., Sebastiano, V., Afshar, P. T., Durruthy, J. D., Lee, L., Williams, B. A., van Bakel, H., Schadt, E. E., Reijo-Pera, R. A., Underwood, J. G., et al. (2013) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 341

Improving PacBio Long Read Accuracy by Short Read Alignment

Au, K. F., Underwood, J. G., Lee, L., & Wong, W. H. (2012) · PLoS ONE

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 335

Modeling non-uniformity in short-read rates in RNA-Seq data

Li, J., Jiang, H., & Wong, W. H. (2010) · Genome Biology

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 193

scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning

Lin, Y., Wu, T.-Y., Wan, S., Yang, J. Y. H., Wong, W. H., & Wang, Y. X. R. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 166

Human transcriptome array for high-throughput clinical studies

Xu, W., Seok, J., Mindrinos, M. N., Schweitzer, A. C., Jiang, H., Wilhelmy, J., Clark, T. A., Kapur, K., Xing, Y., Faham, M., et al. (2011) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 124

Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing

Weirather, J. L., Afshar, P. T., Clark, T. A., Tseng, E., Powers, L. S., Underwood, J. G., Zabner, J., Korlach, J., Wong, W. H., & Au, K. F. (2015) · Nucleic Acids Research

Genomics and Phylogenetic StudiesCancer Genomics and Diagnostics

Cited by 123

Xrare: a machine learning method jointly modeling phenotypes and genetic evidence for rare disease diagnosis

Li, Q., Zhao, K., Bustamante, C. D., Ma, X., & Wong, W. H. (2019) · Genetics in Medicine

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 106

Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage

Zhang, X., Hong, D., Ma, S., Ward, T., Ho, M., Pattni, R., Duren, Z., Stankov, A., Bade Shrestha, S., Hallmayer, J., et al. (2020) · Proceedings of the National Academy of Sciences

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSexual Differentiation and Disorders

Cited by 101

Haplotype-resolved and integrated genome analysis of the cancer cell line HepG2

Zhou, B., Ho, S. S., Greer, S. U., Spies, N., Bell, J. M., Zhang, X., Zhu, X., Arthur, J. G., Byeon, S., Pattni, R., et al. (2019) · Nucleic Acids Research

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 72

Statistical Modeling of RNA-Seq Data

Salzman, J., Jiang, H., & Wong, W. H. (2011) · Statistical Science

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 68

Revealing Free Energy Landscape From MD Data via Conditional Angle Partition Tree

Jiang, H., Li, H., Wong, W. H., & Fan, X. (2023) · IEEE/ACM Transactions on Computational Biology and Bioinformatics

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 4

Revealing Free Energy Landscape from MD Data via Conditional Angle Partition Tree

Jiang, H., Li, H., Wong, W. H., & Fan, X. (2021) · IEEE Transactions on Computational Biology and Bioinformatics

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 4