Nairz, Manfred

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Theurl, I., Aigner, E., Theurl, M., Nairz, M., Seifert, M., Schroll, A., Sonnweber, T., Eberwein, L., Witcher, D. R., Murphy, A. T., et al. (2009) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 421

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine

Phagocytosis and Immune RegulationIron Metabolism and Disorders

Cited by 412

The struggle for iron - a metal at the host-pathogen interface: Iron at the host-pathogen interface

Nairz, M., Schroll, A., Sonnweber, T., & Weiss, G. (2010) · Cellular Microbiology

Iron Metabolism and DisordersIron and Steelmaking Processes

Cited by 398

Iron in infection and immunity

Nairz, M., & Weiss, G. (2020) · Molecular Aspects of Medicine

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 359

Iron at the interface of immunity and infection

Nairz, M., Haschka, D., Demetz, E., & Weiss, G. (2014) · Frontiers in Pharmacology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 325

Autocrine formation of hepcidin induces iron retention in human monocytes

Theurl, I., Theurl, M., Seifert, M., Mair, S., Nairz, M., Rumpold, H., Zoller, H., Bellmann-Weiler, R., Niederegger, H., Talasz, H., et al. (2008) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 275

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

Nairz, M., Schleicher, U., Schroll, A., Sonnweber, T., Theurl, I., Ludwiczek, S., Talasz, H., Brandacher, G., Moser, P. L., Muckenthaler, M. U., et al. (2013) · Journal of Experimental Medicine

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 204

Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways

Nairz, M., Schroll, A., Moschen, A. R., Sonnweber, T., Theurl, M., Theurl, I., Taub, N., Jamnig, C., Neurauter, D., Huber, L. A., et al. (2011) · Immunity

Erythropoietin and Anemia TreatmentNF-κB Signaling Pathways

Cited by 194

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

Theurl, I., Schroll, A., Sonnweber, T., Nairz, M., Theurl, M., Willenbacher, W., Eller, K., Wolf, D., Seifert, M., Sun, C. C., et al. (2011) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 189

The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium

Nairz, M., Theurl, I., Ludwiczek, S., Theurl, M., Mair, S. M., Fritsche, G., & Weiss, G. (2007) · Cellular Microbiology

Iron Metabolism and DisordersBacterial Genetics and Biotechnology

Cited by 182

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels

Nairz, M., Theurl, I., Swirski, F. K., & Weiss, G. (2017) · Pflügers Archiv - European Journal of Physiology

Iron Metabolism and DisordersIron and Steelmaking Processes

Cited by 178

Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study

Sonnweber, T., Boehm, A., Sahanic, S., Pizzini, A., Aichner, M., Sonnweber, B., Kurz, K., Koppelstätter, S., Haschka, D., Petzer, V., et al. (2020) · Respiratory Research

COVID-19 Clinical Research StudiesIron Metabolism and Disorders

Cited by 177

The pleiotropic effects of erythropoietin in infection and inflammation

Nairz, M., Sonnweber, T., Schroll, A., Theurl, I., & Weiss, G. (2012) · Microbes and Infection

Erythropoietin and Anemia TreatmentCytokine Signaling Pathways and Interactions

Cited by 161

Iron deficiency or anemia of inflammation?: Differential diagnosis and mechanisms of anemia of inflammation

Nairz, M., Theurl, I., Wolf, D., & Weiss, G. (2016) · Wiener Medizinische Wochenschrift

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 152

Interferon‐γ limits the availability of iron for intramacrophage Salmonella typhimurium

Nairz, M., Fritsche, G., Brunner, P., Talasz, H., Hantke, K., & Weiss, G. (2008) · European Journal of Immunology

Iron Metabolism and DisordersSalmonella and Campylobacter epidemiology

Cited by 151

Iron in the Tumor Microenvironment-Connecting the Dots

Pfeifhofer-Obermair, C., Tymoszuk, P., Petzer, V., Weiss, G., & Nairz, M. (2018) · Frontiers in Oncology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 151

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

Warszawska, J. M., Gawish, R., Sharif, O., Sigel, S., Doninger, B., Lakovits, K., Mesteri, I., Nairz, M., Boon, L., Spiel, A., et al. (2013) · Journal of Clinical Investigation

Immune cells in cancerImmune Response and Inflammation

Cited by 148

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

Nairz, M., Theurl, I., Schroll, A., Theurl, M., Fritsche, G., Lindner, E., Seifert, M., Crouch, M.-L. V., Hantke, K., Akira, S., et al. (2009) · Blood

Iron Metabolism and DisordersSalmonella and Campylobacter epidemiology

Cited by 146

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Sonnweber, T., Nachbaur, D., Schroll, A., Nairz, M., Seifert, M., Demetz, E., Haschka, D., Mitterstiller, A.-M., Kleinsasser, A., Burtscher, M., et al. (2014) · Gut

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 145

Lipocalin-2 ameliorates granulocyte functionality

Schroll, A., Eller, K., Feistritzer, C., Nairz, M., Sonnweber, T., Moser, P. A., Rosenkranz, A. R., Theurl, I., & Weiss, G. (2012) · European Journal of Immunology

Chemokine receptors and signalingNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 135

Iron and innate antimicrobial immunity-depriving the pathogen, defending the host

Nairz, M., Dichtl, S., Schroll, A., Haschka, D., Tymoszuk, P., Theurl, I., & Weiss, G. (2018) · Journal of Trace Elements in Medicine and Biology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 123

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

Sonnweber, T., Ress, C., Nairz, M., Theurl, I., Schroll, A., Murphy, A. T., Wroblewski, V., Witcher, D. R., Moser, P., Ebenbichler, C. F., et al. (2012) · The Journal of Nutritional Biochemistry

Iron Metabolism and DisordersTrace Elements in Health

Cited by 117

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen

Siegert, I., Schödel, J., Nairz, M., Schatz, V., Dettmer, K., Dick, C., Kalucka, J., Franke, K., Ehrenschwender, M., Schley, G., et al. (2015) · Cell Reports

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 110

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

Nairz, M., Ferring-Appel, D., Casarrubea, D., Sonnweber, T., Viatte, L., Schroll, A., Haschka, D., Fang, F. C., Hentze, M. W., Weiss, G., et al. (2015) · Cell Host & Microbe

Iron Metabolism and DisordersBacterial Genetics and Biotechnology

Cited by 103