Pestell, Richard G.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Naghavi, M., Ong, K. L., Aali, A., Ababneh, H. S., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasian, M., Abbasi-Kangevari, M., Abbastabar, H., et al. (2024) · The Lancet

Insurance, Mortality, Demography, Risk ManagementGlobal Health and Epidemiology

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Stat3 as an Oncogene

Bromberg, J. F., Wrzeszczynska, M. H., Devgan, G., Zhao, Y., Pestell, R. G., Albanese, C., & Darnell, J. E. (1999) · Cell

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

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The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

Shtutman, M., Zhurinsky, J., Simcha, I., Albanese, C., D’Amico, M., Pestell, R., & Ben-Ze’ev, A. (1999) · Proceedings of the National Academy of Sciences

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019

Reitsma, M. B., Kendrick, P. J., Ababneh, E., Abbafati, C., Abbasi-Kangevari, M., Abdoli, A., Abedi, A., Abhilash, E. S., Abila, D. B., Aboyans, V., et al. (2021) · The Lancet

Smoking Behavior and CessationGlobal Cancer Incidence and Screening

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Cancer metabolism: a therapeutic perspective

Martinez-Outschoorn, U. E., Peiris-Pagés, M., Pestell, R. G., Sotgia, F., & Lisanti, M. P. (2017) · Nature Reviews Clinical Oncology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

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The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

Pavlides, S., Whitaker-Menezes, D., Castello-Cros, R., Flomenberg, N., Witkiewicz, A. K., Frank, P. G., Casimiro, M. C., Wang, C., Fortina, P., Addya, S., et al. (2009) · Cell Cycle

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Bhattacharjee, N. V., Schumacher, A. E., Aali, A., Abate, Y. H., Abbasgholizadeh, R., Abbasian, M., Abbasi-Kangevari, M., Abbastabar, H., Abd ElHafeez, S., Abd-Elsalam, S., et al. (2024) · The Lancet

Insurance, Mortality, Demography, Risk ManagementDemographic Trends and Gender Preferences

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Cancer Stem Cell Metabolism

Peiris-Pagès, M., Martinez-Outschoorn, U. E., Pestell, R. G., Sotgia, F., & Lisanti, M. P. (2016) · Breast Cancer Research

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

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Cyclin D1 Is Transcriptionally Regulated by and Required for Transformation by Activated Signal Transducer and Activator of Transcription 3

Leslie, K., Lang, C., Devgan, G., Azare, J., Berishaj, M., Gerald, W., Kim, Y. B., Paz, K., Darnell, J. E., Albanese, C., et al. (2006) · Cancer Research

Cytokine Signaling Pathways and InteractionsCancer-related Molecular Pathways

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Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment

Martinez-Outschoorn, U. E., Pavlides, S., Howell, A., Pestell, R. G., Tanowitz, H. B., Sotgia, F., & Lisanti, M. P. (2011) · The International Journal of Biochemistry & Cell Biology

Cancer, Hypoxia, and MetabolismAutophagy in Disease and Therapy

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CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis

Capparelli, C., Chiavarina, B., Whitaker-Menezes, D., Pestell, T. G., Pestell, R. G., Hulit, J., Andò, S., Howell, A., Martinez-Outschoorn, U. E., Sotgia, F., et al. (2012) · Cell Cycle

Telomeres, Telomerase, and SenescenceAutophagy in Disease and Therapy

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New Roles of Cyclin D1

Pestell, R. G. (2013) · The American Journal of Pathology

Cancer-related Molecular PathwaysSignaling Pathways in Disease

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Recent advances of highly selective CDK4/6 inhibitors in breast cancer

Xu, H., Yu, S., Liu, Q., Yuan, X., Mani, S., Pestell, R. G., & Wu, K. (2017) · Journal of Hematology & Oncology

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

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Energy transfer in "parasitic" cancer metabolism: Mitochondria are the powerhouse and Achilles' heel of tumor cells

Martinez-Outschoorn, U. E., Pestell, R. G., Howell, A., Tykocinski, M. L., Nagajyothi, F., Machado, F. S., Tanowitz, H. B., Sotgia, F., & Lisanti, M. P. (2011) · Cell Cycle

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

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Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype

Galbiati, F., Volonté, D., Chu, J. B., Li, M., Fine, S. W., Fu, M., Bermudez, J., Pedemonte, M., Weidenheim, K. M., Pestell, R. G., et al. (2000) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersCaveolin-1 and cellular processes

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Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling

Migneco, G., Whitaker-Menezes, D., Chiavarina, B., Castello-Cros, R., Pavlides, S., Pestell, R. G., Fatatis, A., Flomenberg, N., Tsirigos, A., Howell, A., et al. (2010) · Cell Cycle

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

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Regulation of the androgen receptor by SET9-mediated methylation.

Gaughan, L., Stockley, J., Wang, N., McCracken, S. R. C., Treumann, A., Armstrong, K., Shaheen, F., Watt, K., McEwan, I. J., Wang, C., et al. (2011) · Nucleic Acids Research

Prostate Cancer Treatment and ResearchCancer-related gene regulation

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Mechanical force modulates global gene expression and β-catenin signaling in colon cancer cells

Avvisato, C. L., Yang, X., Shah, S., Hoxter, B., Li, W., Gaynor, R., Pestell, R., Tozeren, A., & Byers, S. W. (2007) · Journal of Cell Science

Cellular Mechanics and InteractionsWnt/β-catenin signaling in development and cancer

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ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice

Casimiro, M. C., Crosariol, M., Loro, E., Ertel, A., Yu, Z., Dampier, W., Saria, E. A., Papanikolaou, A., Stanek, T. J., Li, Z., et al. (2012) · Journal of Clinical Investigation

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

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Caveolin-1 and Accelerated Host Aging in the Breast Tumor Microenvironment

Mercier, I., Camacho, J., Titchen, K., Gonzales, D. M., Quann, K., Bryant, K. G., Molchansky, A., Milliman, J. N., Whitaker-Menezes, D., Sotgia, F., et al. (2012) · The American Journal of Pathology

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Dietary restriction: standing up for sirtuins

Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., Cabo, R. D., Deng, C., Dimmeler, S., Gius, D., Guarente, L. P., et al. (2010) · Science

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

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Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

Trerotola, M., Ganguly, K. K., Fazli, L., Fedele, C., Lu, H., Dutta, A., Liu, Q., De Angelis, T., Riddell, L. W., Riobo, N. A., et al. (2015) · Oncotarget

Prostate Cancer Treatment and ResearchCell Adhesion Molecules Research

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Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling

Guha, U., Mecklenburg, L., Cowin, P., Kan, L., O'Guin, W. M., D'Vizio, D., Pestell, R. G., Paus, R., & Kessler, J. A. (2004) · The American Journal of Pathology

Hair Growth and Disordersdental development and anomalies

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