Spanagel, Rainer

Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function

Domi, E., Uhrig, S., Soverchia, L., Spanagel, R., Hansson, A. C., Barbier, E., Heilig, M., Ciccocioppo, R., & Ubaldi, M. (2016) · The Journal of Neuroscience

Peroxisome Proliferator-Activated ReceptorsStress Responses and Cortisol

Cited by 61

Enhanced functional activity of the cannabinoid type-1 receptor mediates adolescent behavior

Schneider, M., Kasanetz, F., Lynch, D. L., Friemel, C. M., Lassalle, O., Hurst, D. P., Steindel, F., Monory, K., Schäfer, C., Miederer, I., et al. (2015) · The Journal of Neuroscience

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 56

Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST

Karlsson, R.-M., Adermark, L., Molander, A., Perreau-Lenz, S., Singley, E., Solomon, M., Holmes, A., Tanaka, K., Lovinger, D. M., Spanagel, R., et al. (2012) · Neuropharmacology

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 44

Approved cannabinoids for medical purposes – Comparative systematic review and meta-analysis for sleep and appetite

Spanagel, R., & Bilbao, A. (2021) · Neuropharmacology

Cannabis and Cannabinoid ResearchSleep and related disorders

Cited by 43

Adaptive dynamics of the 5‐HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta‐analysis

Fritze, S., Spanagel, R., & Noori, H. R. (2017) · Journal of Neurochemistry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 42

Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels

Klugmann, M., Klippenstein, V., Leweke, F. M., Spanagel, R., & Schneider, M. (2011) · The International Journal of Neuropsychopharmacology

Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 38

Epigenome-wide association study of alcohol use disorder in five brain regions

Zillich, L., Frank, J., Streit, F., Friske, M. M., Foo, J. C., Sirignano, L., Heilmann-Heimbach, S., Dukal, H., Degenhardt, F., Hoffmann, P., et al. (2022) · Neuropsychopharmacology

Epigenetics and DNA MethylationSubstance Abuse Treatment and Outcomes

Cited by 36

Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles: a longitudinal clinical study

Witt, S. H., Frank, J., Frischknecht, U., Treutlein, J., Streit, F., Foo, J. C., Sirignano, L., Dukal, H., Degenhardt, F., Koopmann, A., et al. (2020) · Addiction

Epigenetics and DNA MethylationAlcohol Consumption and Health Effects

Cited by 35

Low Smoking Exposure, the Adolescent Brain, and the Modulating Role of CHRNA5 Polymorphisms

Chaarani, B., Kan, K.-J., Mackey, S., Spechler, P. A., Potter, A., Orr, C., D’Alberto, N., Hudson, K. E., Banaschewski, T., Bokde, A. L. W., et al. (2019) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 32

Acute and long-term sex-dependent effects of social instability stress on anxiety-like and social behaviours in Wistar rats

Graf, A., Murray, S. H., Eltahir, A., Patel, S., Hansson, A. C., Spanagel, R., & McCormick, C. M. (2023) · Behavioural Brain Research

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 21

Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study

Guiraud, J., Addolorato, G., Aubin, H.-J., Batel, P., de Bejczy, A., Caputo, F., Goudriaan, A. E., Gual, A., Lesch, O., Maremmani, I., et al. (2021) · European Neuropsychopharmacology

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 20