Swinnen, Johannes V.

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

EV-TRACK Consortium, Van Deun, J., Mestdagh, P., Agostinis, P., Akay, Ö., Anand, S., Anckaert, J., Martinez, Z. A., Baetens, T., Beghein, E., et al. (2017) · Nature Methods

Extracellular vesicles in diseaseAcademic Publishing and Open Access

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Lipoprotein lipase links dietary fat to solid tumor cell proliferation

Kuemmerle, N. B., Rysman, E., Lombardo, P. S., Flanagan, A. J., Lipe, B. C., Wells, W. A., Pettus, J. R., Froehlich, H. M., Memoli, V. A., Morganelli, P. M., et al. (2011) · Molecular Cancer Therapeutics

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 286

RNA Interference–Mediated Silencing of the Acetyl-CoA-Carboxylase-α Gene Induces Growth Inhibition and Apoptosis of Prostate Cancer Cells

Brusselmans, K., De Schrijver, E., Verhoeven, G., & Swinnen, J. V. (2005) · Cancer Research

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 277

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

Talebi, A., Dehairs, J., Rambow, F., Rogiers, A., Nittner, D., Derua, R., Vanderhoydonc, F., Duarte, J. A. G., Bosisio, F., Van den Eynde, K., et al. (2018) · Nature Communications

Melanoma and MAPK PathwaysCancer, Lipids, and Metabolism

Cited by 155

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain

Bogie, J. F. J., Grajchen, E., Wouters, E., Corrales, A. G., Dierckx, T., Vanherle, S., Mailleux, J., Gervois, P., Wolfs, E., Dehairs, J., et al. (2020) · Journal of Experimental Medicine

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 151

Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation

Brusselmans, K., Timmermans, L., Van de Sande, T., Van Veldhoven, P. P., Guan, G., Shechter, I., Claessens, F., Verhoeven, G., & Swinnen, J. V. (2007) · Journal of Biological Chemistry

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 116

Evidence From the Aged Orchidectomized Male Rat Model That 17β-Estradiol Is a More Effective Bone-Sparing and Anabolic Agent Than 5α-Dihydrotestosterone

Vandenput, L., Boonen, S., Van Herck, E., Swinnen, J. V., Bouillon, R., & Vanderschueren, D. (2002) · Journal of Bone and Mineral Research

Bone health and osteoporosis researchHormonal and reproductive studies

Cited by 100

An Aged Rat Model of Partial Androgen Deficiency: Prevention of Both Loss of Bone and Lean Body Mass by Low-Dose Androgen Replacement1

Vanderschueren, D., Vandenput, L., Boonen, S., Van Herck, E., Swinnen, J. V., & Bouillon, R. (2000) · Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 88

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

Hamouda, N. N., Van den Haute, C., Vanhoutte, R., Sannerud, R., Azfar, M., Mayer, R., Cortés Calabuig, Á., Swinnen, J. V., Agostinis, P., Baekelandt, V., et al. (2021) · Journal of Biological Chemistry

Polyamine Metabolism and ApplicationsAmino Acid Enzymes and Metabolism

Cited by 85

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells

Martin, S., Dudek-Perić, A. M., Maes, H., Garg, A. D., Gabrysiak, M., Demirsoy, S., Swinnen, J. V., & Agostinis, P. (2015) · Biochemical Pharmacology

Melanoma and MAPK PathwaysAutophagy in Disease and Therapy

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Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis

More, S., Bonnereau, J., Wouters, D., Spotbeen, X., Karras, P., Rizzollo, F., Killian, T., Venken, T., Naulaerts, S., Vervoort, E., et al. (2024) · Science Advances

Ferroptosis and cancer prognosisCancer, Lipids, and Metabolism

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