Sher, Alan

Type I interferons in infectious disease

McNab, F., Mayer-Barber, K., Sher, A., Wack, A., & O'Garra, A. (2015) · Nature Reviews Immunology

interferon and immune responsesImmune Response and Inflammation

Cited by 2,780

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology

Chemokine receptors and signalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 2,632

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

Shi, C.-S., Shenderov, K., Huang, N.-N., Kabat, J., Abu-Asab, M., Fitzgerald, K. A., Sher, A., & Kehrl, J. H. (2012) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

Cited by 1,367

A Critical Role for IL-21 in Regulating Immunoglobulin Production

Ozaki, K., Spolski, R., Feng, C. G., Qi, C.-F., Cheng, J., Sher, A., Morse, H. C., Liu, C., Schwartzberg, P. L., & Leonard, W. J. (2002) · Science

T-cell and B-cell ImmunologyImmunodeficiency and Autoimmune Disorders

Cited by 978

T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

Lighvani, A. A., Frucht, D. M., Jankovic, D., Yamane, H., Aliberti, J., Hissong, B. D., Nguyen, B. V., Gadina, M., Sher, A., Paul, W. E., et al. (2001) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 783

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis

Bafica, A., Scanga, C. A., Feng, C. G., Leifer, C., Cheever, A., & Sher, A. (2005) · The Journal of Experimental Medicine

Tuberculosis Research and EpidemiologyImmune Response and Inflammation

Cited by 601

A major role for ferroptosis in Mycobacterium tuberculosis –induced cell death and tissue necrosis

Amaral, E. P., Costa, D. L., Namasivayam, S., Riteau, N., Kamenyeva, O., Mittereder, L., Mayer-Barber, K. D., Andrade, B. B., & Sher, A. (2019) · Journal of Experimental Medicine

Ferroptosis and cancer prognosisTuberculosis Research and Epidemiology

Cited by 464

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

Mayer-Barber, K. D., Andrade, B. B., Barber, D. L., Hieny, S., Feng, C. G., Caspar, P., Oland, S., Gordon, S., & Sher, A. (2011) · Immunity

Tuberculosis Research and EpidemiologyImmune Response and Inflammation

Cited by 418

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., & Flavell, R. A. (2007) · Immunity

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 396

Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation.

Oswald, I. P., Wynn, T. A., Sher, A., & James, S. L. (1992) · Proceedings of the National Academy of Sciences

Parasites and Host InteractionsCytokine Signaling Pathways and Interactions

Cited by 353

Interferon Consensus Sequence Binding Protein–deficient Mice Display Impaired Resistance to Intracellular Infection Due to a Primary Defect in Interleukin 12 p40 Induction

Scharton-Kersten, T., Contursi, C., Masumi, A., Sher, A., & Ozato, K. (1997) · The Journal of Experimental Medicine

Toxoplasma gondii Research StudiesImmune Response and Inflammation

Cited by 217

Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none

Barber, D. L., Andrade, B. B., Sereti, I., & Sher, A. (2012) · Nature Reviews Microbiology

Infectious Diseases and TuberculosisHIV Research and Treatment

Cited by 169

Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis

Iwamura, C., Bouladoux, N., Belkaid, Y., Sher, A., & Jankovic, D. (2017) · Blood

Hematopoietic Stem Cell TransplantationImmune Response and Inflammation

Cited by 137

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

Moreira-Teixeira, L., Tabone, O., Graham, C. M., Singhania, A., Stavropoulos, E., Redford, P. S., Chakravarty, P., Priestnall, S. L., Suarez-Bonnet, A., Herbert, E., et al. (2020) · Nature Immunology

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 127

Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation

Nelson, N., Kanno, Y., Hong, C., Contursi, C., Fujita, T., Fowlkes, B. J., O’Connell, E., Hu-Li, J., Paul, W. E., Jankovic, D., et al. (1996) · The Journal of Immunology

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 110

Plasma Heme Oxygenase-1 Levels Distinguish Latent or Successfully Treated Human Tuberculosis from Active Disease

Andrade, B. B., Pavan Kumar, N., Mayer-Barber, K. D., Barber, D. L., Sridhar, R., Rekha, V. V. B., Jawahar, M. S., Nutman, T. B., Sher, A., & Babu, S. (2013) · PLoS ONE

Tuberculosis Research and EpidemiologyHeme Oxygenase-1 and Carbon Monoxide

Cited by 64

Processing and presentation of antigens derived from intracellular protozoan parasites

Goldszmid, R. S., & Sher, A. (2010) · Current Opinion in Immunology

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 28