Stehouwer, Coen D.A.

Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

Võsa, U., Claringbould, A., Westra, H.-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Kasela, S., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,607

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Võsa, U., Claringbould, A., Westra, H.-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Yazar, S., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,607

C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction: A Potential Role for Cytokines Originating From Adipose Tissue?

Yudkin, J. S., Stehouwer, C. D. A., Emeis, J. J., & Coppack, S. W. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 2,465

Association of cardiometabolic multimorbidity with mortality

Di Angelantonio, E., Kaptoge, S., Wormser, D., Willeit, P., Butterworth, A. S., Bansal, N., O’Keeffe, L. M., Gao, P., Wood, A. M., Burgess, S., et al. (2015) · JAMA

Chronic Disease Management StrategiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,155

Depression and the risk for cardiovascular diseases: Systematic review and meta analysis

Van der Kooy, K., van Hout, H., Marwijk, H., Marten, H., Stehouwer, C., & Beekman, A. (2007) · International Journal of Geriatric Psychiatry

Cardiac Health and Mental HealthCardiovascular Health and Risk Factors

Cited by 951

Common Carotid Intima-Media Thickness Measurements in Cardiovascular Risk Prediction: A Meta-analysis

Den Ruijter, H. M., Peters, S. A. E., Anderson, T. J., Britton, A. R., Dekker, J. M., Eijkemans, M. J., Engström, G., Evans, G. W., de Graaf, J., Grobbee, D. E., et al. (2012) · JAMA

Cardiovascular Health and Disease PreventionHealth Promotion and Cardiovascular Prevention

Cited by 760

Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression

van Sloten, T. T., Sedaghat, S., Carnethon, M. R., Launer, L. J., & Stehouwer, C. D. A. (2020) · The Lancet Diabetes & Endocrinology

Neurological Disease Mechanisms and TreatmentsBarrier Structure and Function Studies

Cited by 702

Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: Randomised placebo controlled trial

de Jager, J., Kooy, A., Lehert, P., Wulffele, M. G., van der Kolk, J., Bets, D., Verburg, J., Donker, A. J. M., & Stehouwer, C. D. A. (2010) · BMJ

Folate and B Vitamins ResearchPorphyrin Metabolism and Disorders

Cited by 702

Increased Urinary Albumin Excretion, Endothelial Dysfunction, and Chronic Low-Grade Inflammation in Type 2 Diabetes

Stehouwer, C. D. A., Gall, M.-A., Twisk, J. W. R., Knudsen, E., Emeis, J. J., & Parving, H.-H. (2002) · Diabetes

Chronic Kidney Disease and DiabetesAdipokines, Inflammation, and Metabolic Diseases

Cited by 652

Associations of C-Reactive Protein With Measures of Obesity, Insulin Resistance, and Subclinical Atherosclerosis in Healthy, Middle-Aged Women

Hak, A. E., Stehouwer, C. D. A., Bots, M. L., Polderman, K. H., Schalkwijk, C. G., Westendorp, I. C. D., Hofman, A., & Witteman, J. C. M. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 525

Impaired Autonomic Function Is Associated With Increased Mortality, Especially in Subjects With Diabetes, Hypertension, or a History of Cardiovascular Disease

Gerritsen, J., Dekker, J. M., TenVoorde, B. J., Kostense, P. J., Heine, R. J., Bouter, L. M., Heethaar, R. M., & Stehouwer, C. D. A. (2001) · Diabetes Care

Heart Rate Variability and Autonomic ControlCardiovascular Syncope and Autonomic Disorders

Cited by 456

Long-term Effects of Metformin on Metabolism and Microvascular and Macrovascular Disease in Patients With Type 2 Diabetes Mellitus

Kooy, A., de Jager, J., Lehert, P., Bets, D., Wulffelé, M. G., Donker, A. J. M., & Stehouwer, C. D. A. (2009) · Archives of Internal Medicine

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 440

Identification of context-dependent expression quantitative trait loci in whole blood

Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., et al. (2017) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 416

Impaired Microvascular Function in Obesity: Implications for Obesity-Associated Microangiopathy, Hypertension, and Insulin Resistance

de Jongh, R. T., Serné, E. H., IJzerman, R. G., de Vries, G., & Stehouwer, C. D. A. (2004) · Circulation

Cardiovascular and exercise physiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 407

The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus: a systematic review

Wulffelé, M. G., Kooy, A., de Zeeuw, D., Stehouwer, C. D. A., & Gansevoort, R. T. (2004) · Journal of Internal Medicine

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 359

Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

Petrie, J. R., Chaturvedi, N., Ford, I., Brouwers, M. C. G. J., Greenlaw, N., Tillin, T., Hramiak, I., Hughes, A. D., Jenkins, A. J., Klein, B. E. K., et al. (2017) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 357

Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database

Scheijen, J. L. J. M., Clevers, E., Engelen, L., Dagnelie, P. C., Brouns, F., Stehouwer, C. D. A., & Schalkwijk, C. G. (2016) · Food Chemistry

Advanced Glycation End Products researchPotato Plant Research

Cited by 343

Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: A systematic review and meta-analysis

Rensma, S. P., van Sloten, T. T., Launer, L. J., & Stehouwer, C. D. A. (2018) · Neuroscience & Biobehavioral Reviews

Cerebrovascular and genetic disordersDementia and Cognitive Impairment Research

Cited by 326

Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study

van der Berg, J. D., Stehouwer, C. D. A., Bosma, H., van der Velde, J. H. P. M., Willems, P. J. B., Savelberg, H. H. C. M., Schram, M. T., Sep, S. J. S., van der Kallen, C. J. H., Henry, R. M. A., et al. (2016) · Diabetologia

Physical Activity and HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 299

Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification

Schalkwijk, C. G., Stehouwer, C. D. A., & van Hinsbergh, V. W. M. (2004) · Diabetes/Metabolism Research and Reviews

Advanced Glycation End Products researchPotato Plant Research

Cited by 206

Race/ethnic differences in the associations of the framingham risk factors with carotid IMT and cardiovascular events.

Gijsberts, C. M., Groenewegen, K. A., Hoefer, I. E., Eijkemans, M. J. C., Asselbergs, F. W., Anderson, T. J., Britton, A. R., Dekker, J. M., Engström, G., Evans, G. W., et al. (2015) · PLOS ONE

Cardiovascular Health and Disease PreventionCardiovascular Health and Risk Factors

Cited by 197

Estimated Glomerular Filtration Rate and Urinary Albumin Excretion Are Independently Associated with Greater Arterial Stiffness: The Hoorn Study

Hermans, M. M. H., Henry, R., Dekker, J. M., Kooman, J. P., Kostense, P. J., Nijpels, G., Heine, R. J., & Stehouwer, C. D. A. (2007) · Journal of the American Society of Nephrology

Cardiovascular Health and Disease PreventionChronic Kidney Disease and Diabetes

Cited by 196

Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: The Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study

van Woudenbergh, G. J., Theofylaktopoulou, D., Kuijsten, A., Ferreira, I., van Greevenbroek, M. M., van der Kallen, C. J., Schalkwijk, C. G., Stehouwer, C. D., Ocké, M. C., Nijpels, G., et al. (2013) · The American Journal of Clinical Nutrition

Nutritional Studies and DietAdipokines, Inflammation, and Metabolic Diseases

Cited by 190

Markers of inflammation and cellular adhesion molecules in relation to insulin resistance in nondiabetic elderly: The rotterdam study

Hak, A. E., Pols, H. A. P., Stehouwer, C. D. A., Meijer, J., Kiliaan, A. J., Hofman, A., Breteler, M. M. B., & Witteman, J. C. M. (2001) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 184