Knight, Zachary A.

A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

Knight, Z. A., Gonzalez, B., Feldman, M. E., Zunder, E. R., Goldenberg, D. D., Williams, O., Loewith, R., Stokoe, D., Balla, A., Toth, B., et al. (2006) · Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 1,174

Targeting the cancer kinome through polypharmacology

Knight, Z. A., Lin, H., & Shokat, K. M. (2010) · Nature reviews. Cancer

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

Cited by 674

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits

Chen, Y., Lin, Y.-C., Kuo, T.-W., & Knight, Z. A. (2015) · Cell

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 660

Genetic identification of vagal sensory neurons that control feeding

Bai, L., Mesgarzadeh, S., Ramesh, K. S., Huey, E. L., Liu, Y., Gray, L. A., Aitken, T. J., Chen, Y., Beutler, L. R., Ahn, J. S., et al. (2019) · Cell

Regulation of Appetite and ObesityGastrointestinal motility and disorders

Cited by 494

Warm-Sensitive Neurons that Control Body Temperature

Tan, C. L., Cooke, E. K., Leib, D. E., Lin, Y.-C., Daly, G. E., Zimmerman, C. A., & Knight, Z. A. (2016) · Cell

Thermoregulation and physiological responsesRegulation of Appetite and Obesity

Cited by 402

Identification of preoptic sleep neurons using retrograde labelling and gene profiling

Chung, S., Weber, F., Zhong, P., Tan, C. L., Nguyen, T. N., Beier, K. T., Hörmann, N., Chang, W.-C., Zhang, Z., Do, J. P., et al. (2017) · Nature

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 317

Hyperleptinemia Is Required for the Development of Leptin Resistance

Knight, Z. A., Hannan, K. S., Greenberg, M. L., & Friedman, J. M. (2010) · PLoS ONE

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 311

Thirst neurons anticipate the homeostatic consequences of eating and drinking

Zimmerman, C. A., Lin, Y.-C., Leib, D. E., Guo, L., Huey, E. L., Daly, G. E., Chen, Y., & Knight, Z. A. (2016) · Nature

Regulation of Appetite and ObesityNeuroscience of respiration and sleep

Cited by 283

Hunger neurons drive feeding through a sustained, positive reinforcement signal.

Chen, Y., Lin, Y.-C., Zimmerman, C. A., Essner, R. A., & Knight, Z. A. (2016) · eLife

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 196

Sequential appetite suppression by oral and visceral feedback to the brainstem

Ly, T., Oh, J. Y., Sivakumar, N., Shehata, S., La Santa Medina, N., Huang, H., Liu, Z., Fang, W., Barnes, C., Dundar, N., et al. (2023) · Nature

Regulation of Appetite and ObesityNeuroscience of respiration and sleep

Cited by 90

Linking smell to metabolism and aging

Garrison, J. L., & Knight, Z. A. (2017) · Science

Olfactory and Sensory Function StudiesRegulation of Appetite and Obesity

Cited by 38