Ofengeim, Dimitry

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Yuan, J., Amin, P., & Ofengeim, D. (2019) · Nature Reviews Neuroscience

Cell death mechanisms and regulationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 967

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Ito, Y., Ofengeim, D., Najafov, A., Das, S., Saberi, S., Li, Y., Hitomi, J., Zhu, H., Chen, H., Mayo, L., et al. (2016) · Science

Amyotrophic Lateral Sclerosis ResearchCell death mechanisms and regulation

Cited by 606

Activation of Necroptosis in Multiple Sclerosis

Ofengeim, D., Ito, Y., Najafov, A., Zhang, Y., Shan, B., DeWitt, J. P., Ye, J., Zhang, X., Chang, A., Vakifahmetoglu-Norberg, H., et al. (2015) · Cell Reports

Cell death mechanisms and regulationMultiple Sclerosis Research Studies

Cited by 526

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

Xu, D., Jin, T., Zhu, H., Chen, H., Ofengeim, D., Zou, C., Mifflin, L., Pan, L., Amin, P., Li, W., et al. (2018) · Cell

Cell death mechanisms and regulationAmyotrophic Lateral Sclerosis Research

Cited by 461

RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease

Ofengeim, D., Mazzitelli, S., Ito, Y., DeWitt, J. P., Mifflin, L., Zou, C., Das, S., Adiconis, X., Chen, H., Zhu, H., et al. (2017) · Proceedings of the National Academy of Sciences

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 395

Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

Rezaei, A., Kocsis-Jutka, V., Gunes, Z. I., Zeng, Q., Kislinger, G., Bauernschmitt, F., Isilgan, H. B., Parisi, L. R., Kaya, T., Franzenburg, S., et al. (2025) · Nature Communications

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 14