Freije, José M.P.

Metabolic Control of Longevity

López-Otín, C., Galluzzi, L., Freije, J. M. P., Madeo, F., & Kroemer, G. (2016) · Cell

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

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Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

Bárcena, C., Valdés-Mas, R., Mayoral, P., Garabaya, C., Durand, S., Rodríguez, F., Fernández-García, M. T., Salazar, N., Nogacka, A. M., Garatachea, N., et al. (2019) · Nature Medicine

Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms

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Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase–deficient mice

Pendás, A. M., Zhou, Z., Cadiñanos, J., Freije, J. M. P., Wang, J., Hultenby, K., Astudillo, A., Wernerson, A., Rodríguez, F., Tryggvason, K., et al. (2002) · Nature Genetics

Nuclear Structure and FunctionSkin and Cellular Biology Research

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Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation

Varela, I., Cadiñanos, J., Pendás, A. M., Gutiérrez-Fernández, A., Folgueras, A. R., Sánchez, L. M., Zhou, Z., Rodríguez, F. J., Stewart, C. L., Vega, J. A., et al. (2005) · Nature

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

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Splicing-directed therapy in a new mouse model of human accelerated aging

Osorio, F. G., Navarro, C. L., Cadiñanos, J., López-Mejía, I. C., Quirós, P. M., Bartoli, C., Rivera, J., Tazi, J., Guzmán, G., Varela, I., et al. (2011) · Science Translational Medicine

Nuclear Structure and FunctionRNA Research and Splicing

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Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

Osorio, F. G., Bárcena, C., Soria-Valles, C., Ramsay, A. J., de Carlos, F., Cobo, J., Fueyo, A., Freije, J. M. P., & López-Otín, C. (2012) · Genes & Development

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

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Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

Bárcena, C., Quirós, P. M., Durand, S., Mayoral, P., Rodríguez, F., Caravia, X. M., Mariño, G., Garabaya, C., Fernández-García, M. T., Kroemer, G., et al. (2018) · Cell Reports

Genetics, Aging, and Longevity in Model OrganismsNuclear Structure and Function

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