Lee, Jin-Moo

An Updated Definition of Stroke for the 21st Century: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Sacco, R. L., Kasner, S. E., Broderick, J. P., Caplan, L. R., Connors, J. J. (., Culebras, A., Elkind, M. S. V., George, M. G., Hamdan, A. D., Higashida, R. T., et al. (2013) · Stroke

Acute Ischemic Stroke ManagementCerebrovascular and Carotid Artery Diseases

Cited by 3,569

The changing landscape of ischaemic brain injury mechanisms

Lee, J.-M., Zipfel, G. J., & Choi, D. W. (1999) · Nature

Acute Ischemic Stroke ManagementNeuroprotection in Cerebral Ischemia

Cited by 1,102

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

Bero, A. W., Yan, P., Roh, J. H., Cirrito, J. R., Stewart, F. R., Raichle, M. E., Lee, J.-M., & Holtzman, D. M. (2011) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 880

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

Hu, X., Crick, S. L., Bu, G., Frieden, C., Pappu, R. V., & Lee, J.-M. (2009) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 426

Matrix Metalloproteinases Expressed by Astrocytes Mediate Extracellular Amyloid-β Peptide Catabolism

Yin, K.-J., Cirrito, J. R., Yan, P., Hu, X., Xiao, Q., Pan, X., Bateman, R., Song, H., Hsu, F.-F., Turk, J., et al. (2006) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 381

Matrix Metalloproteinase-9 Degrades Amyloid-β Fibrils in Vitro and Compact Plaques in Situ

Yan, P., Hu, X., Song, H., Yin, K., Bateman, R. J., Cirrito, J. R., Xiao, Q., Hsu, F. F., Turk, J. W., Xu, J., et al. (2006) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 380

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

Kraft, A. W., Hu, X., Yoon, H., Yan, P., Xiao, Q., Wang, Y., Gil, S. C., Brown, J., Wilhelmsson, U., Restivo, J. L., et al. (2013) · The FASEB Journal

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 324

Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway

Lee, J.-T., Xu, J., Lee, J.-M., Ku, G., Han, X., Yang, D.-I., Chen, S., & Hsu, C. Y. (2004) · The Journal of Cell Biology

Alzheimer's disease research and treatmentsSphingolipid Metabolism and Signaling

Cited by 280

Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis

Xiao, Q., Yan, P., Ma, X., Liu, H., Perez, R., Zhu, A., Gonzales, E., Burchett, J. M., Schuler, D. R., Cirrito, J. R., et al. (2014) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 266

Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice

Yan, P., Bero, A. W., Cirrito, J. R., Xiao, Q., Hu, X., Wang, Y., Gonzales, E., Holtzman, D. M., & Lee, J.-M. (2009) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 264

Imaging of Functional Connectivity in the Mouse Brain

White, B. R., Bauer, A. Q., Snyder, A. Z., Schlaggar, B. L., Lee, J.-M., & Culver, J. P. (2011) · PLoS ONE

Functional Brain Connectivity StudiesOptical Imaging and Spectroscopy Techniques

Cited by 253

An Antidepressant Decreases CSF Aβ Production in Healthy Individuals and in Transgenic AD Mice

Sheline, Y. I., West, T., Yarasheski, K., Swarm, R., Jasielec, M. S., Fisher, J. R., Ficker, W. D., Yan, P., Xiong, C., Frederiksen, C., et al. (2014) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 223

Spontaneous Infra-slow Brain Activity Has Unique Spatiotemporal Dynamics and Laminar Structure

Mitra, A., Kraft, A., Wright, P., Acland, B., Snyder, A. Z., Rosenthal, Z., Czerniewski, L., Bauer, A., Snyder, L., Culver, J., et al. (2018) · Neuron

Neural dynamics and brain functionFunctional Brain Connectivity Studies

Cited by 193

Role of Phosphatidylinositol Clathrin Assembly Lymphoid-Myeloid Leukemia (PICALM) in Intracellular Amyloid Precursor Protein (APP) Processing and Amyloid Plaque Pathogenesis

Xiao, Q., Gil, S.-C., Yan, P., Wang, Y., Han, S., Gonzales, E., Perez, R., Cirrito, J. R., & Lee, J.-M. (2012) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 166

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking

Fuentealba, R. A., Liu, Q., Zhang, J., Kanekiyo, T., Hu, X., Lee, J.-M., LaDu, M. J., & Bu, G. (2010) · PLoS ONE

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 116

Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease

Fields, M. E., Guilliams, K. P., Ragan, D. K., Binkley, M. M., Eldeniz, C., Chen, Y., Hulbert, M. L., McKinstry, R. C., Shimony, J. S., Vo, K. D., et al. (2018) · Neurology

Hemoglobinopathies and Related DisordersAdvanced MRI Techniques and Applications

Cited by 113

Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease

Yan, P., Kim, K.-W., Xiao, Q., Ma, X., Czerniewski, L. R., Liu, H., Rawnsley, D. R., Yan, Y., Randolph, G. J., Epelman, S., et al. (2022) · Journal of Clinical Investigation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 95

Automated quantification of cerebral edema following hemispheric infarction: application of a machine-learning algorithm to evaluate CSF shifts on serial head CTs

Chen, Y., Dhar, R., Heitsch, L., Ford, A., Fernandez-Cadenas, I., Carrera, C., Montaner, J., Lin, W., Shen, D., An, H., et al. (2016) · NeuroImage: Clinical

Medical Image Segmentation TechniquesAcute Ischemic Stroke Management

Cited by 74

Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome

Heitsch, L., Ibanez, L., Carrera, C., Binkley, M. M., Strbian, D., Tatlisumak, T., Bustamante, A., Ribó, M., Molina, C., Dávalos, A., et al. (2021) · Stroke

Acute Ischemic Stroke ManagementIntracerebral and Subarachnoid Hemorrhage Research

Cited by 70

Rehabilitation Therapy Doses Are Low After Stroke and Predicted by Clinical Factors

Young, B. M., Holman, E. A., Cramer, S. C., Shah, S., Griessenauer, C. J., Patel, N., Lin, D. J., Gee, J., Moon, J., Schwertfeger, J., et al. (2023) · Stroke

Stroke Rehabilitation and RecoveryAcute Ischemic Stroke Management

Cited by 67

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

The Dominantly Inherited Alzheimer Network (DIAN), Li, Z., Del-Aguila, J. L., Dube, U., Budde, J., Martinez, R., Black, K., Xiao, Q., Cairns, N. J., Dougherty, J. D., et al. (2018) · Genome Medicine

Alzheimer's disease research and treatmentsSingle-cell and spatial transcriptomics

Cited by 56

Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model

Liao, F., Jiang, H., Srivatsan, S., Xiao, Q., Lefton, K. B., Yamada, K., Mahan, T. E., Lee, J.-M., Shaw, A. S., & Holtzman, D. M. (2015) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 53

Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy

Guilliams, K. P., Fields, M. E., Ragan, D. K., Chen, Y., Eldeniz, C., Hulbert, M. L., Binkley, M. M., Rhodes, J. N., Shimony, J. S., McKinstry, R. C., et al. (2017) · Pediatric Neurology

Hemoglobinopathies and Related DisordersAdvanced MRI Techniques and Applications

Cited by 51

Effect of escitalopram dose and treatment duration on CSF Aβ levels in healthy older adults: A controlled clinical trial

Sheline, Y. I., Snider, B. J., Beer, J. C., Seok, D., Fagan, A. M., Suckow, R. F., Lee, J.-M., Waligorska, T., Korecka, M., Aselcioglu, I., et al. (2020) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 45