Walker, Brian R.

Glucocorticoids and insulin resistance: old hormones, new targets

ANDREWS, R. C., & WALKER, B. R. (1999) · Clinical Science

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 731

Adrenocortical, Autonomic, and Inflammatory Causes of the Metabolic Syndrome: Nested Case-Control Study

Brunner, E. J., Hemingway, H., Walker, B. R., Page, M., Clarke, P., Juneja, M., Shipley, M. J., Kumari, M., Andrew, R., Seckl, J. R., et al. (2002) · Circulation

Stress Responses and CortisolHeart Rate Variability and Autonomic Control

Cited by 539

Glucocorticoids and cardiovascular disease

Walker, B. R. (2007) · European Journal of Endocrinology

Hormonal Regulation and HypertensionHormonal and reproductive studies

Cited by 529

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

Chau, Y.-Y., Bandiera, R., Serrels, A., Martínez-Estrada, O. M., Qing, W., Lee, M., Slight, J., Thornburn, A., Berry, R., McHaffie, S., et al. (2014) · Nature Cell Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 518

Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Morton, N. M., Paterson, J. M., Masuzaki, H., Holmes, M. C., Staels, B., Fievet, C., Walker, B. R., Flier, J. S., Mullins, J. J., & Seckl, J. R. (2004) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 512

Health status of adults with congenital adrenal hyperplasia: a cohort study of 203 patients

Arlt, W., Willis, D. S., Wild, S. H., Krone, N., Doherty, E. J., Hahner, S., Han, T. S., Carroll, P. V., Conway, G. S., Rees, D. A., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 506

Reduced Cortisol Metabolism during Critical Illness

Boonen, E., Vervenne, H., Meersseman, P., Andrew, R., Mortier, L., Declercq, P. E., Vanwijngaerden, Y.-M., Spriet, I., Wouters, P. J., Vander Perre, S., et al. (2013) · New England Journal of Medicine

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 477

Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome

Macfarlane, D. P., Forbes, S., & Walker, B. R. (2008) · Journal of Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesLipid metabolism and biosynthesis

Cited by 385

Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

Chiswick, C., Reynolds, R. M., Denison, F., Drake, A. J., Forbes, S., Newby, D. E., Walker, B. R., Quenby, S., Wray, S., Weeks, A., et al. (2015) · The Lancet Diabetes & Endocrinology

Gestational Diabetes Research and ManagementPregnancy and Medication Impact

Cited by 260

Subcutaneous Adipose 11β-Hydroxysteroid Dehydrogenase Type 1 Activity and Messenger Ribonucleic Acid Levels Are Associated with Adiposity and Insulinemia in Pima Indians and Caucasians

Lindsay, R. S., Wake, D. J., Nair, S., Bunt, J., Livingstone, D. E. W., Permana, P. A., Tataranni, P. A., & Walker, B. R. (2003) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdrenal Hormones and Disorders

Cited by 225

Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data

Tylee, D. S., Sun, J., Hess, J. L., Tahir, M. A., Sharma, E., Malik, R., Worrall, B. B., Levine, A. J., Martinson, J. J., Nejentsev, S., et al. (2018) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies

Cited by 219

Genotype-phenotype correlation in 153 adult patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: analysis of the United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) cohort

Krone, N., Rose, I. T., Willis, D. S., Hodson, J., Wild, S. H., Doherty, E. J., Hahner, S., Parajes, S., Stimson, R. H., Han, T. S., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 119

Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach

Velders, F. P., Kuningas, M., Kumari, M., Dekker, M. J., Uitterlinden, A. G., Kirschbaum, C., Hek, K., Hofman, A., Verhulst, F. C., Kivimaki, M., et al. (2011) · Psychoneuroendocrinology

Stress Responses and CortisolGenetic Associations and Epidemiology

Cited by 106

Treatment and health outcomes in adults with congenital adrenal hyperplasia

Han, T. S., Walker, B. R., Arlt, W., & Ross, R. J. (2014) · Nature Reviews Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 102

Omental 11β‐hydroxysteroid Dehydrogenase 1 Correlates with Fat Cell Size Independently of Obesity

Michailidou, Z., Jensen, M. D., Dumesic, D. A., Chapman, K. E., Seckl, J. R., Walker, B. R., & Morton, N. M. (2007) · Obesity

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 102

Prenatal dexamethasone programs expression of genes in liver and adipose tissue and increased hepatic lipid accumulation but not obesity on a high-fat diet

Drake, A. J., Raubenheimer, P. J., Kerrigan, D., McInnes, K. J., Seckl, J. R., & Walker, B. R. (2010) · Endocrinology

Birth, Development, and HealthDiet, Metabolism, and Disease

Cited by 97

Ten Years on: Safety of Short Synacthen Tests in Assessing Adrenocorticotropin Deficiency in Clinical Practice

Gleeson, H. K., Walker, B. R., Seckl, J. R., & Padfield, P. L. (2003) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersPituitary Gland Disorders and Treatments

Cited by 85

Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE)

Han, T. S., Krone, N., Willis, D. S., Conway, G. S., Hahner, S., Rees, D. A., Stimson, R. H., Walker, B. R., Arlt, W., Ross, R. J., et al. (2013) · European Journal of Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 79

Genetic variation in 11β-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome

Gambineri, A., Vicennati, V., Genghini, S., Tomassoni, F., Pagotto, U., Pasquali, R., & Walker, B. R. (2006) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersAdrenal Hormones and Disorders

Cited by 75

The postprandial rise in plasma cortisol in men is mediated by macronutrient-specific stimulation of adrenal and extra-adrenal cortisol production

Stimson, R. H., Mohd-Shukri, N. A., Bolton, J. L., Andrew, R., Reynolds, R. M., & Walker, B. R. (2014) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 74

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

Crawford, A. A., Bankier, S., Altmaier, E., Barnes, C. L. K., Clark, D. W., Ermel, R., Friedrich, N., van der Harst, P., Joshi, P. K., Karhunen, V., et al. (2021) · Journal of Human Genetics

Genetic Associations and EpidemiologyStress Responses and Cortisol

Cited by 74

Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia

Han, T. S., Stimson, R. H., Rees, D. A., Krone, N., Willis, D. S., Conway, G. S., Arlt, W., Walker, B. R., Ross, R. J., & (CaHASE), U. K. C. A. H. A. S. E. (2013) · Clinical Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 70

Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women

Goedecke, J. H., Wake, D. J., Levitt, N. S., Lambert, E. V., Collins, M. R., Morton, N. M., Andrew, R., Seckl, J. R., & Walker, B. R. (2006) · Clinical Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 67

Increased Whole-Body and Sustained Liver Cortisol Regeneration by 11β-Hydroxysteroid Dehydrogenase Type 1 in Obese Men With Type 2 Diabetes Provides a Target for Enzyme Inhibition

Stimson, R. H., Andrew, R., McAvoy, N. C., Tripathi, D., Hayes, P. C., & Walker, B. R. (2011) · Diabetes

Hormonal Regulation and HypertensionAdrenal Hormones and Disorders

Cited by 67