Dunker, A. Keith

Intrinsically disordered protein

Dunker, A. K., Lawson, J. D., Brown, C. J., Williams, R. M., Romero, P., Oh, J. S., Oldfield, C. J., Campen, A. M., Ratliff, C. M., Hipps, K. W., et al. (2001) · Journal of Molecular Graphics and Modelling

Protein Structure and DynamicsHeat shock proteins research

Cited by 2,272

Intrinsic Disorder and Protein Function

Dunker, A. K., Brown, C. J., Lawson, J. D., Iakoucheva, L. M., & Obradović, Z. (2002) · Biochemistry

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,731

Intrinsic Disorder in Cell-signaling and Cancer-associated Proteins

Iakoucheva, L. M., Brown, C. J., Lawson, J. D., Obradović, Z., & Dunker, A. K. (2002) · Journal of Molecular Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,214

Flexible nets: The roles of intrinsic disorder in protein interaction networks

Dunker, A. K., Cortese, M. S., Romero, P., Iakoucheva, L. M., & Uversky, V. N. (2005) · The FEBS Journal

Protein Structure and DynamicsBioinformatics and Genomic Networks

Cited by 1,122

Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions

Oldfield, C. J., & Dunker, A. K. (2014) · Annual Review of Biochemistry

Protein Structure and DynamicsHeat shock proteins research

Cited by 1,057

Function and structure of inherently disordered proteins

Dunker, A. K., Silman, I., Uversky, V. N., & Sussman, J. L. (2008) · Current Opinion in Structural Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 963

Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling

Uversky, V. N., Oldfield, C. J., & Dunker, A. K. (2005) · Journal of Molecular Recognition

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 847

Intrinsic Disorder in Transcription Factors

Liu, J., Perumal, N. B., Oldfield, C. J., Su, E. W., Uversky, V. N., & Dunker, A. K. (2006) · Biochemistry

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 792

D2P2: database of disordered protein predictions

Oates, M. E., Romero, P., Ishida, T., Ghalwash, M., Mizianty, M. J., Xue, B., Dosztányi, Z., Uversky, V. N., Obradovic, Z., Kurgan, L., et al. (2012) · Nucleic Acids Research

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 705

The protein trinity—linking function and disorder

Dunker, A. K., & Obradovic, Z. (2001) · Nature Biotechnology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 581

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

Romero, P. R., Zaidi, S., Fang, Y. Y., Uversky, V. N., Radivojac, P., Oldfield, C. J., Cortese, M. S., Sickmeier, M., LeGall, T., Obradovic, Z., et al. (2006) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsRNA Research and Splicing

Cited by 480

The structural and functional signatures of proteins that undergo multiple events of post‐translational modification

Pejaver, V., Hsu, W., Xin, F., Dunker, A. K., Uversky, V. N., & Radivojac, P. (2014) · Protein Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 349

Critical assessment of protein intrinsic disorder prediction

Necci, M., Piovesan, D., Predictors, C., Hoque, M. T., Walsh, I., Iqbal, S., Vendruscolo, M., Sormanni, P., Wang, C., Raimondi, D., et al. (2021) · Nature Methods

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 343

Disorder and Sequence Repeats in Hub Proteins and Their Implications for Network Evolution

Dosztányi, Z., Chen, J., Dunker, A. K., Simon, I., & Tompa, P. (2006) · Journal of Proteome Research

Bioinformatics and Genomic NetworksProtein Structure and Dynamics

Cited by 341

Intrinsically disordered proteins play diverse roles in cell signaling

Bondos, S. E., Dunker, A. K., & Uversky, V. N. (2022) · Cell Communication and Signaling

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 222

Improved amino acid flexibility parameters

Smith, D. K., Radivojac, P., Obradovic, Z., Dunker, A. K., & Zhu, G. (2003) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 164

Intrinsically disordered proteins and multicellular organisms

Dunker, A. K., Bondos, S. E., Huang, F., & Oldfield, C. J. (2015) · Seminars in Cell & Developmental Biology

Protein Structure and DynamicsRNA Research and Splicing

Cited by 150

Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation

Zhou, J., Zhao, S., & Dunker, A. K. (2018) · Journal of Molecular Biology

Protein Structure and DynamicsRNA Research and Splicing

Cited by 90

A Computational Investigation of Allostery in the Catabolite Activator Protein

Li, L., Uversky, V. N., Dunker, A. K., & Meroueh, S. O. (2007) · Journal of the American Chemical Society

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 71

Stochastic machines as a colocalization mechanism for scaffold protein function

Xue, B., Romero, P. R., Noutsou, M., Maurice, M. M., Rüdiger, S. G. D., William, A. M., Mizianty, M. J., Kurgan, L., Uversky, V. N., & Dunker, A. K. (2013) · FEBS Letters

Wnt/β-catenin signaling in development and cancerProtein Structure and Dynamics

Cited by 47