Function and structure of inherently disordered proteins

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

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Intrinsic Disorder and Protein Function

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Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes

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Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

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Flexible nets: The roles of intrinsic disorder in protein interaction networks

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Amyloid ion channels: A common structural link for protein-misfolding disease

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Structure and Dynamics of Micelle-bound Human α-Synuclein

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FoldIndex(C): a simple tool to predict whether a given protein sequence is intrinsically unfolded

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p53 isoforms can regulate p53 transcriptional activity

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Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation

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The interplay between structure and function in intrinsically unstructured proteins

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Intrinsic Disorder and Functional Proteomics

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Structural Biology of the Tumor Suppressor p53

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Quantification of protein half-lives in the budding yeast proteome

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Intrinsic protein disorder in complete genomes.

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Coupled Folding and Binding with α-Helix-Forming Molecular Recognition Elements

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ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins

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Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

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Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic Interactomes

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The protein trinity—linking function and disorder

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Neuropathology, biochemistry, and biophysics of α‐synuclein aggregation

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Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions

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Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes.

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A Protein-Chameleon: Conformational Plasticity of α-Synuclein, a Disordered Protein Involved in Neurodegenerative Disorders

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Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

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Synucleinopathies

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Biophysical Properties of the Synucleins and Their Propensities to Fibrillate

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Evolutionary Rate Heterogeneity in Proteins with Long Disordered Regions

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Local structural disorder imparts plasticity on linear motifs

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Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

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Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins

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Flavors of protein disorder

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What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?

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Disorder and Sequence Repeats in Hub Proteins and Their Implications for Network Evolution

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Mining α-Helix-Forming Molecular Recognition Features with Cross Species Sequence Alignments

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Lipid Binding Inhibits α-Synuclein Fibril Formation

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Protein folding revisited. A polypeptide chain at the folding ? misfolding ? nonfolding cross-roads: which way to go?

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Disordered domains and high surface charge confer hubs with the ability to interact with multiple proteins in interaction networks

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Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

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Handbook of Cell Signaling

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Functional Anthology of Intrinsic Disorder. 2. Cellular Components, Domains, Technical Terms, Developmental Processes, and Coding Sequence Diversities Correlated with Long Disordered Regions

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Prediction of disordered regions in proteins based on the meta approach

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Identifying disordered regions in proteins from amino acid sequence

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Role of Backbone−Solvent Interactions in Determining Conformational Equilibria of Intrinsically Disordered Proteins

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Natively Disordered Proteins

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Amyloidogenesis of Natively Unfolded Proteins

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SLiMFinder: A Probabilistic Method for Identifying Over-Represented, Convergently Evolved, Short Linear Motifs in Proteins

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Dynamics of α‐synuclein aggregation and inhibition of pore‐like oligomer development by β‐synuclein

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Handbook of Cell Signaling

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Amyloid β Protein (1−40) Forms Calcium-Permeable, Zn 2+ -Sensitive Channel in Reconstituted Lipid Vesicles ,

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Helical α-Synuclein Forms Highly Conductive Ion Channels

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Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions

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Assessment of disorder predictions in CASP7

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Urea Promotes Polyproline II Helix Formation: Implications for Protein Denatured States

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Structural disorder serves as a weak signal for intracellular protein degradation

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Intrinsic unstructuredness and abundance of PEST motifs in eukaryotic proteomes

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Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome

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Proportion of Solvent-Exposed Amino Acids in a Protein and Rate of Protein Evolution

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Molecular determinants of the aggregation behavior of α‐ and β‐synuclein

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Dynamic Behavior of an Intrinsically Unstructured Linker Domain Is Conserved in the Face of Negligible Amino Acid Sequence Conservation

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An antiaggregation gene therapy strategy for Lewy body disease utilizing β-synuclein lentivirus in a transgenic model

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Residual structure in disordered peptides and unfolded proteins from multivariate analysis and ab initio simulation of Raman optical activity data

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Correlation of Amyloid Fibril β‐Structure with the Unfolded State of α‐Synuclein

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Prediction of Protein Disorder

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Hierarchical Extensibility in the PEVK Domain of Skeletal-Muscle Titin

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The intracellular domain of the Drosophila cholinesterase‐like neural adhesion protein, gliotactin, is natively unfolded

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Biophysical Characterization of the Unstructured Cytoplasmic Domain of the Human Neuronal Adhesion Protein Neuroligin 3

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Signaling to the p53 Tumor Suppressor through Pathways Activated by Genotoxic and Non-Genotoxic Stresses

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Unwinding the helical linker of calcium‐loaded calmodulin: A molecular dynamics study

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Packing Regularities in Biological Structures Relate to Their Dynamics

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Structural consequences of an amino acid deletion in the B1 domain of protein G

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

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The proteostasis network and its decline in ageing

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The Cell–Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression

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The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

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D2P2: database of disordered protein predictions

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Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

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Tissue-specific alternative splicing remodels protein-protein interaction networks

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A code within the genetic code: codon usage regulates co-translational protein folding

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Firefly luciferase mutants as sensors of proteome stress

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Intrinsically disordered proteins play diverse roles in cell signaling

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Temperature-dependent solvation modulates the dimensions of disordered proteins

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Intrinsically disordered proteins and multicellular organisms

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Allosteric Modulators of Steroid Hormone Receptors: Structural Dynamics and Gene Regulation

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Finding Our Way in the Dark Proteome

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The development of biomolecular Raman optical activity spectroscopy

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Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation

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