Ayton, Scott

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Overcoming the Blood–Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

Furtado, D., Björnmalm, M., Ayton, S., Bush, A. I., Kempe, K., & Caruso, F. (2018) · Advanced Materials

Barrier Structure and Function StudiesNanoparticle-Based Drug Delivery

Cited by 708

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Lei, P., Ayton, S., Finkelstein, D. I., Spoerri, L., Ciccotosto, G. D., Wright, D. K., Wong, B. X. W., Adlard, P. A., Cherny, R. A., Lam, L. Q., et al. (2012) · Nature Medicine

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 594

Current state of Alzheimer’s fluid biomarkers

Molinuevo, J. L., Ayton, S., Batrla, R., Bednar, M. M., Bittner, T., Cummings, J., Fagan, A. M., Hampel, H., Mielke, M. M., Mikulskis, A., et al. (2018) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 518

Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion

Tuo, Q.-Z., Liu, Y., Xiang, Z., Yan, H.-F., Zou, T., Shu, Y., Ding, X.-L., Zou, J.-J., Xu, S., Tang, F., et al. (2022) · Signal Transduction and Targeted Therapy

Ferroptosis and cancer prognosisNeuroprotection in Cerebral Ischemia

Cited by 330

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

Ayton, S., Lei, P., Duce, J. A., Wong, B. X. W., Sedjahtera, A., Adlard, P. A., Bush, A. I., & Finkelstein, D. I. (2013) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 264

GSK‐3 in Neurodegenerative Diseases

Lei, P., Ayton, S., Bush, A. I., & Adlard, P. A. (2011) · International Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsWnt/β-catenin signaling in development and cancer

Cited by 177

Motor and cognitive deficits in aged tau knockout mice in two background strains

Lei, P., Ayton, S., Moon, S., Zhang, Q., Volitakis, I., Finkelstein, D. I., & Bush, A. I. (2014) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 145

Selective ferroptosis vulnerability due to familial Alzheimer’s disease presenilin mutations

Greenough, M. A., Lane, D. J. R., Balez, R., Anastacio, H. T. D., Zeng, Z., Ganio, K., McDevitt, C. A., Acevedo, K., Belaidi, A. A., Koistinaho, J., et al. (2022) · Cell Death & Differentiation

Alzheimer's disease research and treatmentsFerroptosis and cancer prognosis

Cited by 102

Type‐1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease

Main, B. S., Zhang, M., Brody, K. M., Ayton, S., Frugier, T., Steer, D., Finkelstein, D., Crack, P. J., & Taylor, J. M. (2016) · Glia

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 92

Apolipoprotein E in Alzheimer’s disease: molecular insights and therapeutic opportunities

Belaidi, A. A., Bush, A. I., & Ayton, S. (2025) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 91

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

Belaidi, A. A., Gunn, A. P., Wong, B. X., Ayton, S., Appukuttan, A. T., Roberts, B. R., Duce, J. A., & Bush, A. I. (2018) · Neurotherapeutics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 83

The link between amyloid β and ferroptosis pathway in Alzheimer’s disease progression

Majerníková, N., Marmolejo-Garza, A., Salinas, C. S., Luu, M. D. A., Zhang, Y., Trombetta-Lima, M., Tomin, T., Birner-Gruenberger, R., Lehtonen, Š., Koistinaho, J., et al. (2024) · Cell Death & Disease

Alzheimer's disease research and treatmentsFerroptosis and cancer prognosis

Cited by 73

β-amyloid: The known unknowns

Ayton, S., & Bush, A. I. (2021) · Ageing Research Reviews

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 45