Beuers, Ulrich

Microbiome-derived ethanol in nonalcoholic fatty liver disease

Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., et al. (2022) · Nature Medicine

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 215

Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double‐blind, randomised, placebo‐controlled, crossover, phase 2a study

Hegade, V. S., Kendrick, S. F. W., Dobbins, R. L., Miller, S. R., Thompson, D., Richards, D., Storey, J., Dukes, G. E., Corrigan, M., Oude Elferink, R. P. J., et al. (2017) · The Lancet

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 206

Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: a multicenter, randomized, double-blind, placebo-controlled phase II trial

Hirschfield, G. M., Chazouillères, O., Drenth, J. P., Thorburn, D., Harrison, S. A., Landis, C. S., Mayo, M. J., Muir, A. J., Trotter, J. F., Leeming, D. J., et al. (2019) · Journal of Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 187

Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial

Pose, E., Napoleone, L., Amin, A., Campion, D., Jimenez, C., Piano, S., Roux, O., Uschner, F. E., de Wit, K., Zaccherini, G., et al. (2020) · The Lancet Gastroenterology & Hepatology

Liver Disease and TransplantationLiver Disease Diagnosis and Treatment

Cited by 154

High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective

Cullen, S. N., Rust, C., Fleming, K., Edwards, C., Beuers, U., & Chapman, R. W. (2008) · Journal of Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 136

The potent bile acid sequestrant colesevelam is not effective in cholestatic pruritus: results of a double-blind, randomized, placebo-controlled trial

Kuiper, E. M. M., van Erpecum, K. J., Beuers, U., Hansen, B. E., Thio, B. H., de Man, R. A., Janssen, H. L. A., & van Buuren, H. R. (2010) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 132

Exposure to occupational antigens might predispose to IgG4-related disease

de Buy Wenniger, L. J. M., Culver, E. L., & Beuers, U. (2014) · Hepatology

IgG4-Related and Inflammatory DiseasesLiver Diseases and Immunity

Cited by 124

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

Reich, M., Spomer, L., Klindt, C., Fuchs, K., Stindt, J., Deutschmann, K., Höhne, J., Liaskou, E., Hov, J. R., Karlsen, T. H., et al. (2021) · Journal of Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 121

Novel therapeutic targets in primary biliary cirrhosis

Dyson, J. K., Hirschfield, G. M., Adams, D. H., Beuers, U., Mann, D. A., Lindor, K. D., & Jones, D. E. J. (2015) · Nature Reviews Gastroenterology & Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 120

The challenges of primary biliary cholangitis: What is new and what needs to be done

Terziroli Beretta-Piccoli, B., Mieli-Vergani, G., Vergani, D., Vierling, J. M., Adams, D., Alpini, G., Banales, J. M., Beuers, U., Björnsson, E., Bowlus, C., et al. (2019) · Journal of Autoimmunity

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 114

Rising incidence and prevalence of primary biliary cirrhosis: a large population-based study

Boonstra, K., Kunst, A. E., Stadhouders, P. H., Tuynman, H. A., Poen, A. C., van Nieuwkerk, K. M. J., Witteman, E. M., Hamann, D., Witteman, B. J., Beuers, U., et al. (2014) · Liver International

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 112

A placebo-controlled randomised trial of budesonide for PBC following an insufficient response to UDCA

Hirschfield, G. M., Beuers, U., Kupcinskas, L., Ott, P., Bergquist, A., Färkkilä, M., Manns, M. P., Parés, A., Spengler, U., Stiess, M., et al. (2021) · Journal of Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 108

Changing nomenclature for PBC: from ‘cirrhosis’ to ‘cholangitis’

Beuers, U., Gershwin, M. E., Gish, R. G., Invernizzi, P., Jones, D. E. J., Lindor, K., Ma, X., Mackay, I. R., Parés, A., Tanaka, A., et al. (2015) · Journal of Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 97

Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter Ntcp

Donkers, J. M., Zehnder, B., van Westen, G. J. P., Kwakkenbos, M. J., IJzerman, A. P., Oude Elferink, R. P. J., Beuers, U., Urban, S., & van de Graaf, S. F. J. (2017) · Scientific Reports

Hepatitis B Virus StudiesDrug Transport and Resistance Mechanisms

Cited by 90

Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study

de Vries, E. M. G., Färkkilä, M., Milkiewicz, P., Hov, J. R., Eksteen, B., Thorburn, D., Chazouillères, O., Pares, A., Nygård, S., Gilja, O. H., et al. (2017) · Liver International

Liver Diseases and ImmunityLiver Disease Diagnosis and Treatment

Cited by 83

Pregnancy in primary sclerosing cholangitis

Wellge, B. E., Sterneck, M., Teufel, A., Rust, C., Franke, A., Schreiber, S., Berg, T., Günther, R., Kreisel, W., zu Eulenburg, C., et al. (2011) · Gut

Liver Diseases and ImmunityPregnancy and Medication Impact

Cited by 76

Na + -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice

Slijepcevic, D., Roscam Abbing, R. L. P., Fuchs, C. D., Haazen, L. C. M., Beuers, U., Trauner, M., Oude Elferink, R. P. J., & van de Graaf, S. F. J. (2018) · Hepatology

Drug Transport and Resistance MechanismsLiver physiology and pathology

Cited by 73

Soluble adenylyl cyclase regulates bile salt-induced apoptosis in human cholangiocytes

Chang, J., Go, S., de Waart, D. R., Munoz‐Garrido, P., Beuers, U., Paulusma, C. C., & Oude Elferink, R. (2016) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 70

Unmet clinical need in autoimmune liver diseases

Dyson, J. K., Webb, G., Hirschfield, G. M., Lohse, A., Beuers, U., Lindor, K., & Jones, D. E. J. (2015) · Journal of Hepatology

Liver Diseases and ImmunityIgG4-Related and Inflammatory Diseases

Cited by 66

Characterization of organic anion transporter regulation, glutathione metabolism and bile formation in the obese Zucker rat

Geier, A., Dietrich, C. G., Grote, T., Beuers, U., Prüfer, T., Fraunberger, P., Matern, S., Gartung, C., Gerbes, A. L., & Bilzer, M. (2005) · Journal of Hepatology

Drug Transport and Resistance MechanismsLiver Disease Diagnosis and Treatment

Cited by 66

Endoscopic duodenal mucosal resurfacing improves glycaemic and hepatic indices in type 2 diabetes: 6-month multicentre results

van Baar, A. C. G., Beuers, U., Wong, K., Haidry, R., Costamagna, G., Hafedi, A., Deviere, J., Ghosh, S. S., Lopez-Talavera, J. C., Rodriguez, L., et al. (2019) · JHEP Reports

Bariatric Surgery and OutcomesDiabetes Treatment and Management

Cited by 55

Comparable efficacy of low- versus high-dose induction corticosteroid treatment in autoimmune pancreatitis

Buijs, J., van Heerde, M. J., Rauws, E. A. J., de Buy Wenniger, L. J. M., Hansen, B. E., Biermann, K., Verheij, J., Vleggaar, F. P., Brink, M. A., Beuers, U. H. W., et al. (2014) · Pancreas

IgG4-Related and Inflammatory DiseasesVasculitis and related conditions

Cited by 51

Plasma separation and anion adsorption transiently relieve intractable pruritus in primary biliary cirrhosis

Pusl, T., Denk, G. U., Parhofer, K. G., & Beuers, U. (2006) · Journal of Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 50

Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'

Beuers, U., Gershwin, M. E., Gish, R. G., Invernizzi, P., Jones, D. E. J., Lindor, K., Ma, X., Mackay, I. R., Parés, A., Tanaka, A., et al. (2015) · Clinics and Research in Hepatology and Gastroenterology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 43