Hoffmann, Markus

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 20,286

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

Hoffmann, M., Kleine-Weber, H., & Pöhlmann, S. (2020) · Molecular Cell

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 1,852

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

Hoffmann, M., Arora, P., Groß, R., Seidel, A., Hörnich, B. F., Hahn, A. S., Krüger, N., Graichen, L., Hofmann-Winkler, H., Kempf, A., et al. (2021) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 897

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

Hoffmann, M., Krüger, N., Schulz, S., Cossmann, A., Rocha, C., Kempf, A., Nehlmeier, I., Graichen, L., Moldenhauer, A.-S., Winkler, M. S., et al. (2022) · Cell

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 889

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

Wrapp, D., De Vlieger, D., Corbett, K. S., Torres, G. M., Wang, N., Van Breedam, W., Roose, K., van Schie, L., Hoffmann, M., Pöhlmann, S., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 610

Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination

Barros-Martins, J., Hammerschmidt, S. I., Cossmann, A., Odak, I., Stankov, M. V., Morillas Ramos, G., Dopfer-Jablonka, A., Heidemann, A., Ritter, C., Friedrichsen, M., et al. (2021) · Nature Medicine

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 425

SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination

Hoffmann, M., Hofmann-Winkler, H., Krüger, N., Kempf, A., Nehlmeier, I., Graichen, L., Arora, P., Sidarovich, A., Moldenhauer, A.-S., Winkler, M. S., et al. (2021) · Cell Reports

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 258

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells

Carpinteiro, A., Edwards, M. J., Hoffmann, M., Kochs, G., Gripp, B., Weigang, S., Adams, C., Carpinteiro, E., Gulbins, A., Keitsch, S., et al. (2020) · Cell Reports Medicine

SARS-CoV-2 and COVID-19 ResearchSphingolipid Metabolism and Signaling

Cited by 184

Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation

Hoffmann, M., Behrens, G. M. N., Arora, P., Kempf, A., Nehlmeier, I., Cossmann, A., Manthey, L., Dopfer-Jablonka, A., & Pöhlmann, S. (2023) · The Lancet Infectious Diseases

SARS-CoV-2 and COVID-19 ResearchVaccine Coverage and Hesitancy

Cited by 66

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein

Shilts, J., Crozier, T. W. M., Teixeira-Silva, A., Gabaev, I., Greenwood, E. J. D., Watson, S. J., Ortmann, B. M., Gawden-Bone, C. M., Pauzaite, T., Hoffmann, M., et al. (2021) · PLoS Biology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 28

SARS-CoV-2 delta variant neutralisation after heterologous ChAdOx1-S/BNT162b2 vaccination

Behrens, G. M., Cossmann, A., Stankov, M. V., Nehlmeier, I., Kempf, A., Hoffmann, M., & Pöhlmann, S. (2021) · The Lancet

SARS-CoV-2 and COVID-19 ResearchVaccine Coverage and Hesitancy

Cited by 27

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

Kim, Y., Zheng, X., Eschke, K., Chaudhry, M. Z., Bertoglio, F., Tomić, A., Krmpotić, A., Hoffmann, M., Bar-On, Y., Boehme, J., et al. (2022) · Cellular & Molecular Immunology

Cytomegalovirus and herpesvirus researchInfluenza Virus Research Studies

Cited by 14