Lehrach, Hans

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments

Richard, H., Schulz, M. H., Sultan, M., Nürnberger, A., Schrinner, S., Balzereit, D., Dagand, E., Rasche, A., Lehrach, H., Vingron, M., et al. (2010) · Nucleic Acids Research

RNA Research and SplicingGenomics and Phylogenetic Studies

Cited by 160

Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model

Fröhlich, F., Kessler, T., Weindl, D., Shadrin, A., Schmiester, L., Hache, H., Muradyan, A., Schütte, M., Lim, J.-H., Heinig, M., et al. (2018) · Cell Systems

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 143

A gene expression map of human chromosome 21 orthologues in the mouse

initiative, T. H. E. M., *Group 1:, Gitton, Y., Dahmane, N., Baik, S., Ruiz i Altaba, A., *Group 2:, Neidhardt, L., Scholze, M., Herrmann, B. G., et al. (2002) · Nature

Down syndrome and intellectual disability researchDevelopmental Biology and Gene Regulation

Cited by 127

Characterizing the mouse ES cell transcriptome with Illumina sequencing

Rosenkranz, R., Borodina, T., Lehrach, H., & Himmelbauer, H. (2008) · Genomics

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 106

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

Jäger, N., Schlesner, M., Jones, D. T. W., Raffel, S., Mallm, J.-P., Junge, K. M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., et al. (2013) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 90

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos

Neidhardt, L., Gasca, S., Wertz, K., Obermayr, F., Worpenberg, S., Lehrach, H., & Herrmann, B. G. (2000) · Mechanisms of Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 79

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

Sultan, M., Piccini, I., Balzereit, D., Herwig, R., Saran, N. G., Lehrach, H., Reeves, R. H., & Yaspo, M.-L. (2007) · Genome Biology

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 78

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo

Harrison, S. M., Dunwoodie, S. L., Arkell, R. M., Lehrach, H., & Beddington, R. S. P. (1995) · Development

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 71

Onset of Immune Senescence Defined by Unbiased Pyrosequencing of Human Immunoglobulin mRNA Repertoires

Rubelt, F., Sievert, V., Knaust, F., Diener, C., Lim, T. S., Skriner, K., Klipp, E., Reinhardt, R., Lehrach, H., & Konthur, Z. (2012) · PLoS ONE

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 37

Public Health Perspective: From Personalized Medicine to Personal Health

Cesuroglu, T., van Ommen, B., Malats, N., Sudbrak, R., Lehrach, H., & Brand, A. (2012) · Personalized Medicine

Technology and Human Factors in Education and HealthScience, Research, and Medicine

Cited by 23

Expression profiling of drug response - from genes to pathways

Herwig, R., & Lehrach, H. (2006) · Dialogues in Clinical Neuroscience

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 14

Transcriptional signature induced by a metastasis‐promoting c‐Src mutant in a human breast cell line

Broecker, F., Hardt, C., Herwig, R., Timmermann, B., Kerick, M., Wunderlich, A., Schweiger, M. R., Borsig, L., Heikenwalder, M., Lehrach, H., et al. (2016) · The FEBS Journal

Mechanisms of cancer metastasisCancer Mechanisms and Therapy

Cited by 9