Melnick, Ari

Notch activation inhibits AML growth and survival: a potential therapeutic approach

Kannan, S., Sutphin, R. M., Hall, M. G., Golfman, L. S., Fang, W., Nolo, R. M., Akers, L. J., Hammitt, R. A., McMurray, J. S., Kornblau, S. M., et al. (2013) · Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchDevelopmental Biology and Gene Regulation

Cited by 152

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Chen, Z., Shojaee, S., Buchner, M., Geng, H., Lee, J. W., Klemm, L., Titz, B., Graeber, T. G., Park, E., Tan, Y. X., et al. (2015) · Nature

Acute Lymphoblastic Leukemia researchT-cell and B-cell Immunology

Cited by 149

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Glass, J. L., Hassane, D., Wouters, B. J., Kunimoto, H., Avellino, R., Garrett-Bakelman, F. E., Guryanova, O. A., Bowman, R., Redlich, S., Intlekofer, A. M., et al. (2017) · Cancer Discovery

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 142

Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region

Bunting, K. L., Soong, T. D., Singh, R., Jiang, Y., Béguelin, W., Poloway, D. W., Swed, B. L., Hatzi, K., Reisacher, W., Teater, M., et al. (2016) · Immunity

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 141

TBL1XR1 mutations drive extranodal lymphoma by inducing a pro-tumorigenic memory fate

Venturutti, L., Teater, M., Zhai, A., Chadburn, A., Babiker, L., Kim, D., Béguelin, W., Lee, T. C., Kim, Y., Chin, C. R., et al. (2020) · Cell

Lymphoma Diagnosis and TreatmentT-cell and B-cell Immunology

Cited by 127

Kaiso Contributes to DNA Methylation-Dependent Silencing of Tumor Suppressor Genes in Colon Cancer Cell Lines

Lopes, E. C., Valls, E., Figueroa, M. E., Mazur, A., Meng, F.-G., Chiosis, G., Laird, P. W., Schreiber-Agus, N., Greally, J. M., Prokhortchouk, E., et al. (2008) · Cancer Research

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 119

BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells

Ranuncolo, S. M., Polo, J. M., & Melnick, A. (2008) · Blood Cells, Molecules, and Diseases

Lymphoma Diagnosis and TreatmentDNA Repair Mechanisms

Cited by 116

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma

Green, M. R., Vicente-Dueñas, C., Romero-Camarero, I., Long Liu, C., Dai, B., González-Herrero, I., García-Ramírez, I., Alonso-Escudero, E., Iqbal, J., Chan, W. C., et al. (2014) · Nature Communications

Lymphoma Diagnosis and TreatmentViral-associated cancers and disorders

Cited by 88

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers

Bezdan, D., Grigorev, K., Meydan, C., Pelissier Vatter, F. A., Cioffi, M., Rao, V., MacKay, M., Nakahira, K., Burnham, P., Afshinnekoo, E., et al. (2020) · iScience

Spaceflight effects on biologyExtracellular vesicles in disease

Cited by 59

Molecular pathogenesis of acute promyelocytic leukaemia and APL variants

Sirulnik, A., Melnick, A., Zelent, A., & Licht, J. D. (2003) · Best Practice & Research Clinical Haematology

Retinoids in leukemia and cellular processesAcute Myeloid Leukemia Research

Cited by 54

Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma

Carrasco-Leon, A., Ezponda, T., Meydan, C., Valcárcel, L. V., Ordoñez, R., Kulis, M., Garate, L., Miranda, E., Segura, V., Guruceaga, E., et al. (2021) · Leukemia

Multiple Myeloma Research and TreatmentsCancer-related molecular mechanisms research

Cited by 50

Differential gene body methylation and reduced expression of cell adhesion and neurotransmitter receptor genes in adverse maternal environment

Oh, J.-E., Chambwe, N., Klein, S., Gal, J., Andrews, S., Gleason, G., Shaknovich, R., Melnick, A., Campagne, F., & Toth, M. (2013) · Translational Psychiatry

Epigenetics and DNA MethylationMaternal Mental Health During Pregnancy and Postpartum

Cited by 43

Mutant IDH : A Targetable Driver of Leukemic Phenotypes Linking Metabolism, Epigenetics and Transcriptional Regulation

Garrett-Bakelman, F. E., & Melnick, A. M. (2016) · Epigenomics

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 25

Gene expression derived from alternative promoters improves prognostic stratification in multiple myeloma

Valcárcel, L. V., Amundarain, A., Kulis, M., Charalampopoulou, S., Melnick, A., San Miguel, J., Martín-Subero, J. I., Planes, F. J., Agirre, X., & Prosper, F. (2021) · Leukemia

Multiple Myeloma Research and TreatmentsGenomics and Chromatin Dynamics

Cited by 17