Feng, Felix Y.

Integrative Clinical Genomics of Advanced Prostate Cancer

Robinson, D., Van Allen, E. M., Wu, Y.-M., Schultz, N., Lonigro, R. J., Mosquera, J.-M., Montgomery, B., Taplin, M.-E., Pritchard, C. C., Attard, G., et al. (2015) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 3,645

The landscape of long noncoding RNAs in the human transcriptome

Iyer, M. K., Niknafs, Y. S., Malik, R., Singhal, U., Sahu, A., Hosono, Y., Barrette, T. R., Prensner, J. R., Evans, J. R., Zhao, S., et al. (2015) · Nature Genetics

Cancer-related molecular mechanisms researchGenomics and Phylogenetic Studies

Cited by 2,738

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

Mateo, J., Carreira, S., Sandhu, S., Miranda, S., Mossop, H., Perez-Lopez, R., Nava Rodrigues, D., Robinson, D., Omlin, A., Tunariu, N., et al. (2015) · New England Journal of Medicine

PARP inhibition in cancer therapyProstate Cancer Treatment and Research

Cited by 2,185

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study

Aggarwal, R., Huang, J., Alumkal, J. J., Zhang, L., Feng, F. Y., Thomas, G. V., Weinstein, A. S., Friedl, V., Zhang, C., Witte, O. N., et al. (2018) · Journal of Clinical Oncology

Prostate Cancer Treatment and ResearchNeuroblastoma Research and Treatments

Cited by 810

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J. J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., et al. (2018) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 733

Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer

Shipley, W. U., Seiferheld, W., Lukka, H. R., Major, P. P., Heney, N. M., Grignon, D. J., Sartor, O., Patel, M. P., Bahary, J.-P., Zietman, A. L., et al. (2017) · New England Journal of Medicine

Prostate Cancer Diagnosis and TreatmentProstate Cancer Treatment and Research

Cited by 663

Widespread and Functional RNA Circularization in Localized Prostate Cancer

Chen, S., Huang, V., Xu, X., Livingstone, J., Soares, F., Jeon, J., Zeng, Y., Hua, J. T., Petricca, J., Guo, H., et al. (2019) · Cell

Circular RNAs in diseasesRNA Research and Splicing

Cited by 544

Racial/ethnic disparities in genomic sequencing

Spratt, D. E., Chan, T., Waldron, L., Speers, C., Feng, F. Y., Ogunwobi, O. O., & Osborne, J. R. (2016) · JAMA Oncology

Cancer Genomics and DiagnosticsRace, Genetics, and Society

Cited by 375

Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer

Parolia, A., Cieslik, M., Chu, S.-C., Xiao, L., Ouchi, T., Zhang, Y., Wang, X., Vats, P., Cao, X., Pitchiaya, S., et al. (2019) · Nature

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 284

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer

Guo, H., Ahmed, M., Zhang, F., Yao, C. Q., Li, S., Liang, Y., Hua, J., Soares, F., Sun, Y., Langstein, J., et al. (2016) · Nature Genetics

Cancer-related molecular mechanisms researchProstate Cancer Treatment and Research

Cited by 226

Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors

Hovelson, D. H., McDaniel, A. S., Cani, A. K., Johnson, B., Rhodes, K., Williams, P. D., Bandla, S., Bien, G., Choppa, P., Hyland, F., et al. (2015) · Neoplasia

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 224

Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials

Esteva, A., Feng, J., van der Wal, D., Huang, S.-C., Simko, J. P., DeVries, S., Chen, E., Schaeffer, E. M., Morgan, T. M., Sun, Y., et al. (2022) · npj Digital Medicine

Radiomics and Machine Learning in Medical ImagingAI in cancer detection

Cited by 217

Integrative epigenetic taxonomy of primary prostate cancer

Stelloo, S., Nevedomskaya, E., Kim, Y., Schuurman, K., Valle-Encinas, E., Lobo, J., Krijgsman, O., Peeper, D. S., Chang, S. L., Feng, F. Y.-C., et al. (2018) · Nature Communications

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 154

Artificial intelligence predictive model for hormone therapy use in prostate cancer

Spratt, D. E., Tang, S., Sun, Y., Huang, H.-C., Chen, E., Mohamad, O., Armstrong, A. J., Tward, J. D., Nguyen, P. L., Lang, J. M., et al. (2023) · NEJM Evidence

Prostate Cancer Diagnosis and TreatmentRadiomics and Machine Learning in Medical Imaging

Cited by 153

Management of patients with advanced prostate cancer: report from the Advanced Prostate Cancer Consensus Conference 2021

Gillessen, S., Armstrong, A., Attard, G., Beer, T. M., Beltran, H., Bjartell, A., Bossi, A., Briganti, A., Bristow, R. G., Bulbul, M., et al. (2022) · European Urology

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 130

Single-dose 177Lu-PSMA-617 followed by maintenance pembrolizumab in patients with metastatic castration-resistant prostate cancer: an open-label, dose-expansion, phase 1 trial

Aggarwal, R., Starzinski, S., de Kouchkovsky, I., Koshkin, V., Bose, R., Chou, J., Desai, A., Kwon, D., Kaushal, S., Trihy, L., et al. (2023) · The Lancet Oncology

Prostate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and Applications

Cited by 104

A Novel RNA In Situ Hybridization Assay for the Long Noncoding RNA SChLAP1 Predicts Poor Clinical Outcome After Radical Prostatectomy in Clinically Localized Prostate Cancer

Mehra, R., Shi, Y., Udager, A. M., Prensner, J. R., Sahu, A., Iyer, M. K., Siddiqui, J., Cao, X., Wei, J., Jiang, H., et al. (2014) · Neoplasia

Cancer-related molecular mechanisms researchProstate Cancer Treatment and Research

Cited by 95

False positive PSMA PET for tumor remnants in the irradiated prostate and other interpretation pitfalls in a prospective multi-center trial

Fendler, W. P., Calais, J., Eiber, M., Simko, J. P., Kurhanewicz, J., Santos, R. D., Feng, F. Y., Reiter, R. E., Rettig, M. B., Nickols, N. G., et al. (2021) · European Journal of Nuclear Medicine and Molecular Imaging

Prostate Cancer Diagnosis and TreatmentRadiopharmaceutical Chemistry and Applications

Cited by 56

Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial

Spratt, D. E., Liu, V. Y. T., Michalski, J., Davicioni, E., Berlin, A., Simko, J. P., Efstathiou, J. A., Tran, P. T., Sandler, H. M., Hall, W. A., et al. (2023) · International Journal of Radiation Oncology*Biology*Physics

Prostate Cancer Diagnosis and TreatmentBreast Cancer Treatment Studies

Cited by 45

An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer

Das, R., Sjöström, M., Shrestha, R., Yogodzinski, C., Egusa, E. A., Chesner, L. N., Chen, W. S., Chou, J., Dang, D. K., Swinderman, J. T., et al. (2021) · Nature Communications

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 38

External validation of a digital pathology-based multimodal artificial intelligence architecture in the NRG/RTOG 9902 phase 3 trial

Ross, A. E., Zhang, J., Huang, H.-C., Yamashita, R., Keim-Malpass, J., Simko, J. P., DeVries, S., Morgan, T. M., Souhami, L., Dobelbower, M. C., et al. (2024) · European Urology Oncology

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

Cited by 35

Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy

Karnes, R. J., Sharma, V., Choeurng, V., Ashab, H. A.-D., Erho, N., Alshalalfa, M., Trock, B., Ross, A., Yousefi, K., Tsai, H., et al. (2018) · Clinical Cancer Research

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 30

Validation of an artificial intelligence-based prognostic biomarker in patients with oligometastatic Castration-Sensitive prostate cancer

Wang, J. H., Deek, M. P., Mendes, A. A., Song, Y., Shetty, A., Bazyar, S., Van der Eecken, K., Chen, E., Showalter, T. N., Royce, T. J., et al. (2025) · Radiotherapy and Oncology

Prostate Cancer Treatment and ResearchRadiomics and Machine Learning in Medical Imaging

Cited by 25

Consequence of the tumor-associated conversion to cyclin D1b

Augello, M. A., Berman‐Booty, L. D., Carr, R., Yoshida, A., Dean, J. L., Schiewer, M. J., Feng, F. Y., Tomlins, S. A., Gao, E., Koch, W. J., et al. (2015) · EMBO Molecular Medicine

Cancer-related Molecular PathwaysSignaling Pathways in Disease

Cited by 23