Irvine, Elaine E.

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Selman, C., Tullet, J. M. A., Wieser, D., Irvine, E., Lingard, S. J., Choudhury, A. I., Claret, M., Al-Qassab, H., Carmignac, D., Ramadani, F., et al. (2009) · Science

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 1,120

Cardiac glycosides are broad-spectrum senolytics

Guerrero, A., Herranz, N., Sun, B., Wagner, V., Gallage, S., Guiho, R., Wolter, K., Pombo, J., Irvine, E. E., Innes, A. J., et al. (2019) · Nature Metabolism

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 359

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

Katsouri, L., Lim, Y. M., Blondrath, K., Eleftheriadou, I., Lombardero, L., Birch, A. M., Mirzaei, N., Irvine, E. E., Mazarakis, N. D., & Sastre, M. (2016) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 146

αCaMKII autophosphorylation contributes to rapid learning but is not necessary for memory

Irvine, E. E., Vernon, J., & Giese, K. P. (2005) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 119

The dorsal raphe nucleus is a crucial structure mediating nicotine's anxiolytic effects and the development of tolerance and withdrawal responses

Cheeta, S., Irvine, E. E., Kenny, P. J., & File, S. E. (2001) · Psychopharmacology

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 113

Mechanism for long-term memory formation when synaptic strengthening is impaired

Radwanska, K., Medvedev, N. I., Pereira, G. S., Engmann, O., Thiede, N., Moraes, M. F. D., Villers, A., Irvine, E. E., Maunganidze, N. S., Pyza, E. M., et al. (2011) · Proceedings of the National Academy of Sciences

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 97

Time-course of changes in the social interaction test of anxiety following acute and chronic administration of nicotine

Irvine, E. E., Cheeta, S., & File, S. E. (1999) · Behavioural Pharmacology

Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

Cited by 89

Tolerance to nicotine's effects in the elevated plus-maze and increased anxiety during withdrawal

Irvine, E. E., Cheeta, S., & File, S. E. (2001) · Pharmacology Biochemistry and Behavior

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 88

Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression

Angelo, M., Plattner, F., Irvine, E. E., & Giese, K. P. (2003) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsMemory and Neural Mechanisms

Cited by 82

Social isolation modifies nicotine's effects in animal tests of anxiety

Cheeta, S., Irvine, E., & File, S. E. (2001) · British Journal of Pharmacology

Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

Cited by 71

NMDA receptor‐dependent long‐term potentiation in mouse hippocampal interneurons shows a unique dependence on Ca 2+ /calmodulin‐dependent kinases

Lamsa, K., Irvine, E. E., Giese, K. P., & Kullmann, D. M. (2007) · The Journal of Physiology

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 61

The ATM Cofactor ATMIN Protects against Oxidative Stress and Accumulation of DNA Damage in the Aging Brain

Kanu, N., Penicud, K., Hristova, M., Wong, B., Irvine, E., Plattner, F., Raivich, G., & Behrens, A. (2010) · Journal of Biological Chemistry

DNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 55

Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

Gallage, S., Irvine, E. E., Pedroni, S. M. A., Barragan Avila, J. E., Khadayate, S., Pombo, J., Brookes, S., Heide, D., Dharmalingham, G., Choudhury, A. I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 31