Clark, Anne

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

Cooper, G. J., Willis, A. C., Clark, A., Turner, R. C., Sim, R. B., & Reid, K. B. (1987) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesAlzheimer's disease research and treatments

Cited by 1,299

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Brereton, M. F., Iberl, M., Shimomura, K., Zhang, Q., Adriaenssens, A. E., Proks, P., Spiliotis, I. I., Dace, W., Mattis, K. K., Ramracheya, R., et al. (2014) · Nature Communications

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 259

γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells

Braun, M., Ramracheya, R., Bengtsson, M., Clark, A., Walker, J. N., Johnson, P. R., & Rorsman, P. (2010) · Diabetes

Pancreatic function and diabetesNeuroscience and Neuropharmacology Research

Cited by 239

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus

McCulloch, L. J., van de Bunt, M., Braun, M., Frayn, K. N., Clark, A., & Gloyn, A. L. (2011) · Molecular Genetics and Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 207

Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?

Brereton, M. F., Vergari, E., Zhang, Q., & Clark, A. (2015) · Journal of Histochemistry & Cytochemistry

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 206

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca 2+ channels

Ramracheya, R., Chapman, C., Chibalina, M., Dou, H., Miranda, C., González, A., Moritoh, Y., Shigeto, M., Zhang, Q., Braun, M., et al. (2018) · Physiological Reports

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 128

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells

Brereton, M. F., Rohm, M., Shimomura, K., Holland, C., Tornovsky-Babeay, S., Dadon, D., Iberl, M., Chibalina, M. V., Lee, S., Glaser, B., et al. (2016) · Nature Communications

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 124

Islet amyloid polypeptide in diabetic and non-diabetic Pima Indians

Clark, A., Saad, M. F., Nezzer, T., Uren, C., Knowler, W. C., Bennett, P. H., & Turner, R. C. (1990) · Diabetologia

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 119

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes

Girard, C. A., Wunderlich, F. T., Shimomura, K., Collins, S., Kaizik, S., Proks, P., Abdulkader, F., Clark, A., Ball, V., Zubcevic, L., et al. (2008) · Journal of Clinical Investigation

Pancreatic function and diabetesIon channel regulation and function

Cited by 105

Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells

Braun, M., Wendt, A., Karanauskaite, J., Galvanovskis, J., Clark, A., MacDonald, P. E., & Rorsman, P. (2007) · The Journal of General Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 100

Is Type 2 Diabetes a Glycogen Storage Disease of Pancreatic β Cells?

Ashcroft, F. M., Rohm, M., Clark, A., & Brereton, M. F. (2017) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 84

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

Collins, S. C., Hoppa, M. B., Walker, J. N., Amisten, S., Abdulkader, F., Bengtsson, M., Fearnside, J., Ramracheya, R., Toye, A. A., Zhang, Q., et al. (2010) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 73

Kiss-and-run exocytosis and fusion pores of secretory vesicles in human β-cells

Hanna, S. T., Pigeau, G. M., Galvanovskis, J., Clark, A., Rorsman, P., & MacDonald, P. E. (2009) · Pflügers Archiv - European Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 57

Reversibility of metabolic and morphological changes associated with chronic exposure of pancreatic islet β‐cells to fatty acids

Pinnick, K., Neville, M., Clark, A., & Fielding, B. (2010) · Journal of Cellular Biochemistry

Pancreatic function and diabetesLipid metabolism and biosynthesis

Cited by 55

GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

Gandasi, N. R., Gao, R., Kothegala, L., Pearce, A., Santos, C., Acreman, S., Basco, D., Benrick, A., Chibalina, M. V., Clark, A., et al. (2024) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 31