Cagan, Alex

Somatic mutant clones colonize the human esophagus with age

Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K., Stratton, M. R., et al. (2018) · Science

Cancer Genomics and DiagnosticsEsophageal Cancer Research and Treatment

Cited by 1,113

SARS-CoV-2 evolution during treatment of chronic infection

Kemp, S. A., Collier, D. A., Datir, R. P., Ferreira, I. A. T. M., Gayed, S., Jahun, A., Hosmillo, M., Rees-Spear, C., Mlcochova, P., Lumb, I. U., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 1,097

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

Young, M. D., Mitchell, T. J., Vieira Braga, F. A., Tran, M. G. B., Stewart, B. J., Ferdinand, J. R., Collord, G., Botting, R. A., Popescu, D.-M., Loudon, K. W., et al. (2018) · Science

Single-cell and spatial transcriptomicsRenal cell carcinoma treatment

Cited by 762

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R. P., Walls, A. C., Kemp, S. A., Bassi, J., Pinto, D., Silacci-Fregni, C., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 728

Somatic mutation rates scale with lifespan across mammals

Cagan, A., Baez-Ortega, A., Brzozowska, N., Abascal, F., Coorens, T. H. H., Sanders, M. A., Lawson, A. R. J., Harvey, L. M. R., Bhosle, S., Jones, D., et al. (2021) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer Genomics and Diagnostics

Cited by 482

Somatic mutation rates scale with lifespan across mammals

Cagan, A., Baez-Ortega, A., Brzozowska, N., Abascal, F., Coorens, T. H. H., Sanders, M. A., Lawson, A. R. J., Harvey, L. M. R., Bhosle, S., Jones, D., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer Genomics and Diagnostics

Cited by 481

The mutational landscape of human somatic and germline cells

Moore, L., Cagan, A., Coorens, T. H. H., Neville, M. D. C., Sanghvi, R., Sanders, M. A., Oliver, T. R. W., Leongamornlert, D., Ellis, P., Noorani, A., et al. (2021) · Nature

Cancer Genomics and DiagnosticsDNA Repair Mechanisms

Cited by 379

Extensive heterogeneity in somatic mutation and selection in the human bladder

Lawson, A. R. J., Abascal, F., Coorens, T. H. H., Hooks, Y., O’Neill, L., Latimer, C., Raine, K., Sanders, M. A., Warren, A. Y., Mahbubani, K. T. A., et al. (2020) · Science

Cancer Genomics and DiagnosticsBladder and Urothelial Cancer Treatments

Cited by 311

Diverse mutational landscapes in human lymphocytes

Machado, H. E., Mitchell, E., Øbro, N. F., Kübler, K., Davies, M., Leongamornlert, D., Cull, A., Maura, F., Sanders, M. A., Cagan, A. T. J., et al. (2022) · Nature

Cancer Genomics and DiagnosticsDNA Repair Mechanisms

Cited by 116

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids

Georgakopoulos, N., Prior, N., Angres, B., Mastrogiovanni, G., Cagan, A., Harrison, D., Hindley, C. J., Arnes-Benito, R., Liau, S.-S., Curd, A., et al. (2020) · BMC Developmental Biology

Pancreatic function and diabetesPancreatic and Hepatic Oncology Research

Cited by 112

Identification of genomic variants putatively targeted by selection during dog domestication

Cagan, A., & Blass, T. (2016) · BMC Evolutionary Biology

Human-Animal Interaction StudiesGenetic and phenotypic traits in livestock

Cited by 69

Evolution of the Pygmy Phenotype: Evidence of Positive Selection from Genome-wide Scans in African, Asian, and Melanesian Pygmies

Migliano, A. B., Romero, I. G., Metspalu, M., Leavesley, M., Pagani, L., Antao, T., Huang, D.-W., Sherman, B. T., Siddle, K., Scholes, C., et al. (2013) · Human Biology

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 23