Frye, Richard E.

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012) · Translational Psychiatry

Autism Spectrum Disorder ResearchRedox biology and oxidative stress

Cited by 480

Melatonin in autism spectrum disorders: a systematic review and meta-analysis

ROSSIGNOL, D. A., & FRYE, R. E. (2011) · Developmental Medicine & Child Neurology

Autism Spectrum Disorder ResearchCircadian rhythm and melatonin

Cited by 468

Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review

Deepmala, Slattery, J., Kumar, N., Delhey, L., Berk, M., Dean, O., Spielholz, C., & Frye, R. (2015) · Neuroscience & Biobehavioral Reviews

Sulfur Compounds in BiologyTreatment of Major Depression

Cited by 463

Environmental toxicants and autism spectrum disorders: a systematic review

Rossignol, D. A., Genuis, S. J., & Frye, R. E. (2014) · Translational Psychiatry

Autism Spectrum Disorder ResearchHeavy Metal Exposure and Toxicity

Cited by 458

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies

Hamdan, F. F., Myers, C. T., Cossette, P., Lemay, P., Spiegelman, D., Laporte, A. D., Nassif, C., Diallo, O., Monlong, J., Cadieux-Dion, M., et al. (2017) · The American Journal of Human Genetics

Epilepsy research and treatmentGenetics and Neurodevelopmental Disorders

Cited by 445

Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism

Rose, S., Bennuri, S. C., Davis, J. E., Wynne, R., Slattery, J. C., Tippett, M., Delhey, L., Melnyk, S., Kahler, S. G., MacFabe, D. F., et al. (2018) · Translational Psychiatry

Mitochondrial Function and PathologyAutism Spectrum Disorder Research

Cited by 226

Touch, sound and vision in human superior temporal sulcus

Beauchamp, M. S., Yasar, N. E., Frye, R. E., & Ro, T. (2008) · NeuroImage

Multisensory perception and integrationTactile and Sensory Interactions

Cited by 208

Oxidative Stress Induces Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines in a Well-Matched Case Control Cohort

Rose, S., Frye, R. E., Slattery, J., Wynne, R., Tippett, M., Pavliv, O., Melnyk, S., & James, S. J. (2014) · PLoS ONE

Mitochondrial Function and PathologyAutism Spectrum Disorder Research

Cited by 168

Mitochondrial Dysfunction in Autism Spectrum Disorder: Unique Abnormalities and Targeted Treatments

Frye, R. E. (2020) · Seminars in Pediatric Neurology

Autism Spectrum Disorder ResearchMitochondrial Function and Pathology

Cited by 161

Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines

Frye, R. E., Rose, S., Chacko, J., Wynne, R., Bennuri, S. C., Slattery, J. C., Tippett, M., Delhey, L., Melnyk, S., Kahler, S. G., et al. (2016) · Translational Psychiatry

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 130

Metabolic and mitochondrial disorders associated with epilepsy in children with Autism Spectrum Disorder

Frye, R. E. (2015) · Epilepsy & Behavior

Autism Spectrum Disorder ResearchMetabolism and Genetic Disorders

Cited by 117

Editorial: Comorbidity and Autism Spectrum Disorder

Casanova, M. F., Frye, R. E., Gillberg, C., & Casanova, E. L. (2020) · Frontiers in Psychiatry

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 110

Identification and treatment of pathophysiological comorbidities of autism spectrum disorder to achieve optimal outcomes

Frye, R. E., & Rossignol, D. A. (2016) · Clinical Medicine Insights Pediatrics

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 96

Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: A blinded case-control study

Rose, S., Bennuri, S. C., Murray, K. F., Buie, T., Winter, H., & Frye, R. E. (2017) · PLOS ONE

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 82

The Use of Medications Approved for Alzheimer’s Disease in Autism Spectrum Disorder: A Systematic Review

Rossignol, D. A., & Frye, R. E. (2014) · Frontiers in Pediatrics

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 79

Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism

Connery, K., Tippett, M., Delhey, L. M., Rose, S., Slattery, J. C., Kahler, S. G., Hahn, J., Kruger, U., Cunningham, M. W., Shimasaki, C., et al. (2018) · Translational Psychiatry

Autoimmune Neurological Disorders and TreatmentsAutism Spectrum Disorder Research

Cited by 64

Multimodal quantitative magnetic resonance imaging of thalamic development and aging across the human lifespan: implications to neurodegeneration in multiple sclerosis

Hasan, K. M., Walimuni, I. S., Abid, H., Frye, R. E., Ewing-Cobbs, L., Wolinsky, J. S., & Narayana, P. A. (2011) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesAdvanced Neuroimaging Techniques and Applications

Cited by 64

Evaluation of the Cunningham Panel™ in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS): Changes in antineuronal antibody titers parallel changes in patient symptoms

Shimasaki, C., Frye, R. E., Trifiletti, R., Cooperstock, M., Kaplan, G., Melamed, I., Greenberg, R., Katz, A., Fier, E., Kem, D., et al. (2020) · Journal of Neuroimmunology

Autoimmune Neurological Disorders and TreatmentsStreptococcal Infections and Treatments

Cited by 61

Clustering of co-occurring conditions in autism spectrum disorder during early childhood: A retrospective analysis of medical claims data

Vargason, T., Frye, R. E., McGuinness, D. L., & Hahn, J. (2019) · Autism Research

Autism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

Cited by 59

Rating of the effectiveness of 26 psychiatric and seizure medications for autism spectrum disorder: Results of a national survey

Coleman, D. M., Adams, J. B., Anderson, A. L., & Frye, R. E. (2019) · Journal of Child and Adolescent Psychopharmacology

Autism Spectrum Disorder ResearchAttention Deficit Hyperactivity Disorder

Cited by 56

Modulation of Immunological Pathways in Autistic and Neurotypical Lymphoblastoid Cell Lines by the Enteric Microbiome Metabolite Propionic Acid

Frye, R. E., Nankova, B., Bhattacharyya, S., Rose, S., Bennuri, S. C., & MacFabe, D. F. (2017) · Frontiers in Immunology

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 51

Enteric ecosystem disruption in autism spectrum disorder: Can the microbiota and macrobiota be restored?

Slattery, J., MacFabe, D., Kahler, S., & Frye, R. (2016) · Current Pharmaceutical Design

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 20