Rakugi, Hiromi

The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)

Umemura, S., Arima, H., Arima, S., Asayama, K., Dohi, Y., Hirooka, Y., Horio, T., Hoshide, S., Ikeda, S., Ishimitsu, T., et al. (2019) · Hypertension Research

Blood Pressure and Hypertension StudiesClinical practice guidelines implementation

Cited by 1,880

Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis

Rahimi, K., Bidel, Z., Nazarzadeh, M., Copland, E., Canoy, D., Ramakrishnan, R., Pinho-Gomes, A.-C., Woodward, M., Adler, A., Agodoa, L., et al. (2021) · The Lancet

Blood Pressure and Hypertension StudiesSodium Intake and Health

Cited by 1,074

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., et al. (2022) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 825

Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017

Kinoshita, M., Yokote, K., Arai, H., Iida, M., Ishigaki, Y., Ishibashi, S., Umemoto, S., Egusa, G., Ohmura, H., Okamura, T., et al. (2018) · Journal of Atherosclerosis and Thrombosis

Lipoproteins and Cardiovascular HealthHealth Promotion and Cardiovascular Prevention

Cited by 813

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

Kimura, T., Takabatake, Y., Takahashi, A., Kaimori, J.-Y., Matsui, I., Namba, T., Kitamura, H., Niimura, F., Matsusaka, T., Soga, T., et al. (2011) · Journal of the American Society of Nephrology

Autophagy in Disease and TherapyAcute Kidney Injury Research

Cited by 461

Source of chronic inflammation in aging

Sanada, F., Taniyama, Y., Muratsu, J., Otsu, R., Shimizu, H., Rakugi, H., & Morishita, R. (2018) · Frontiers in Cardiovascular Medicine

Genetics, Aging, and Longevity in Model OrganismsInflammasome and immune disorders

Cited by 413

Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma

Kimura, N., Takayanagi, R., Takizawa, N., Itagaki, E., Katabami, T., Kakoi, N., Rakugi, H., Ikeda, Y., Tanabe, A., Nigawara, T., et al. (2014) · Endocrine Related Cancer

Adrenal and Paraganglionic TumorsNeuroendocrine Tumor Research Advances

Cited by 393

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

Takahashi, A., Kimura, T., Takabatake, Y., Namba, T., Kaimori, J., Kitamura, H., Matsui, I., Niimura, F., Matsusaka, T., Fujita, N., et al. (2012) · The American Journal of Pathology

Autophagy in Disease and TherapyChemotherapy-induced organ toxicity mitigation

Cited by 253

Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized, Controlled Trial

Ouchi, Y., Sasaki, J., Arai, H., Yokote, K., Harada, K., Katayama, Y., Urabe, T., Uchida, Y., Hayashi, M., Yokota, N., et al. (2019) · Circulation

Lipoproteins and Cardiovascular HealthBlood Pressure and Hypertension Studies

Cited by 231

The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice

Yoshida, S., Nakagami, H., Hayashi, H., Ikeda, Y., Sun, J., Tenma, A., Tomioka, H., Kawano, T., Shimamura, M., Morishita, R., et al. (2020) · Nature Communications

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 161

Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule

Yamamoto, T., Takabatake, Y., Kimura, T., Takahashi, A., Namba, T., Matsuda, J., Minami, S., Kaimori, J.-Y., Matsui, I., Kitamura, H., et al. (2016) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 135

Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model

Takeda, S., Sato, N., Ikimura, K., Nishino, H., Rakugi, H., & Morishita, R. (2013) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 135

β 2 - and β 3 -Adrenergic Receptor Polymorphisms Are Related to the Onset of Weight Gain and Blood Pressure Elevation Over 5 Years

Masuo, K., Katsuya, T., Fu, Y., Rakugi, H., Ogihara, T., & Tuck, M. L. (2005) · Circulation

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 123

Angiotensin II type 1 receptor-mediated peroxide production in human macrophages

Yanagitani, Y., Rakugi, H., Okamura, A., Moriguchi, K., Takiuchi, S., Ohishi, M., Suzuki, K., Higaki, J., & Ogihara, T. (1999) · Hypertension

Renin-Angiotensin System StudiesNitric Oxide and Endothelin Effects

Cited by 118

Local production of activated factor X in atherosclerotic plaque induced vascular smooth muscle cell senescence

Sanada, F., Muratsu, J., Otsu, R., Shimizu, H., Koibuchi, N., Uchida, K., Taniyama, Y., Yoshimura, S., Rakugi, H., & Morishita, R. (2017) · Scientific Reports

Blood Coagulation and Thrombosis MechanismsAtherosclerosis and Cardiovascular Diseases

Cited by 41

Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo‐controlled, double‐blind study

Akasaka, H., Nakagami, H., Sugimoto, K., Yasunobe, Y., Minami, T., Fujimoto, T., Yamamoto, K., Hara, C., Shiraki, A., Nishida, K., et al. (2023) · Geriatrics & Gerontology International

Sirtuins and Resveratrol in MedicineNutrition and Health in Aging

Cited by 34

The Importance of Stroke as a Risk Factor of Cognitive Decline in Community Dwelling Older and Oldest peoples : The SONIC Study

Srithum, W., Kabayama, M., Gondo, Y., Masui, Y., Akagi, Y., Klinpudtan, N., Kiyoshige, E., Godai, K., Sugimoto, K., Akasaka, H., et al. (2020) · BMC Geriatrics

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 24